Navigation Links
Newly approved oral medication slows rheumatoid arthritis joint damage
Date:1/23/2013

ference from placebo in mean change from baseline in the van der Heijde modified total Sharp score was statistically significant for tofacitinib at 10 mg BID but not at 5 mg BID at month 6 (co-primary endpoint) and month 12.

Patients treated with tofacitinib at both 5 and 10 mg BID doses displayed less progression of joint erosion and joint space narrowing compared to placebo at six and twelve months. Change in the joint space narrowing score was statistically significant at month 12 for the tofacitinib groups versus placebo. Researchers also reported that the proportion of patients with no radiographic progression in the tofacitinib groups was significantly greater compared to placebo.

Analysis confirms previous results that tofacitinib is effective in treating RA symptoms and reducing the rate of joint damage. "Our findings provide the first evidence that tofacitinib reduces the progression of structural damage in RA patients with active disease," concludes Dr. van der Heijde.

The U.S. Food and Drug Administration (FDA) approved tofacitinibthe first oral JAK inhibitor for treatment of moderate to severe RAon November 6, 2012. A twice daily 5 mg dose of tofacitinib was approved by the FDA for RA patients who are unresponsive or intolerant to MTX. The drug is being marketed by Pfizer as Xeljanz.


'/>"/>

Contact: Dawn Peters
sciencenewsroom@wiley.com
781-388-8408
Wiley
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Neurological Wellness Center Pays Tribute to Newly Released Study Announcing TBI Treatment Breakthrough
2. Newly Updated 'Critical Bench' Teaches People How to Gain Muscle, Says Tony Nguyen
3. Newly Launched Blenderreviews101.com - The Best and Complete Resource for Blender Reviews
4. Newly Released “H Miracle” Can Teach People How to Cure Hemorrhoids, Says Health Review Center
5. Neurological Wellness Center's Novel Neuro-Inflammation Inhibition Procedure that Induces Rapid Recovery from Alzheimer's, Stroke and Brain Injury is Now Being Taught in a Newly Released Video
6. The Newly Updated "The Diet Solution Program" Helps People Lose Body Fat, Says Health Review Center
7. Newly Released ProSkin 2.0 and ProMood Final Cut Pro X Plugins at Pixel Film Studios
8. Newly insured patients may have trouble finding primary care physicians
9. Moffitt Cancer Center melanoma expert reviews unique adverse events with newly approved drug
10. Study: 21 percent of newly admitted nursing home residents sustain a fall during their stay
11. Newly Aggressive Dogs May Be Reacting to Pain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... Os-Monitor.com, an outstanding online supplier ... employee monitoring software collection ( http://www.os-monitor.com ). In ... that all these high end items are offered ... tendency of improving productivity, the employers pay more ... Thus, employee and network monitoring software products are ...
(Date:8/21/2014)... New York (PRWEB) August 22, 2014 ... for the Long Island region, proudly announces the launch ... site, focused on the West Babylon-based yoga studio’s new ... who wish to become teachers realize their dreams. , ... community and those living in the surrounding area a ...
(Date:8/21/2014)... August 22, 2014 The natural loss of ... lines, wrinkles and sagging of skin. Using products to ... age 40, the body has lost about 15% of it ... 45%," says Kathy Heshelow, founder of Sublime Beauty®. "Collagen ... it - well, we know what happens." , Collagen in ...
(Date:8/21/2014)... 2014 Strongly influenced by their ... when there are no consequences, researchers in Georgia ... , This could imply that humans are less ... others, researchers said. Their findings are published in ... sense of unfairness is affected by their self-interest, ...
(Date:8/21/2014)... Top10BestSEOHosting.com has compared many professional SEO hosting companies and ... most reliable suppliers for webmasters who want to buy ... in websites in recent years, and the new demand ... web hosting companies that offer a variety of different ... providing hosting solutions to thousands of business and personal ...
Breaking Medicine News(10 mins):Health News:New Employee Monitoring Software Collection Unveiled By Os-Monitor.com 2Health News:Yoga Darshana Center Announces Launch of New Website LongIslandYogaTeacherTraining.com 2Health News:4 Skincare Products That Boost and Nurture Collagen on Sale at Sublime Beauty® 2Health News:4 Skincare Products That Boost and Nurture Collagen on Sale at Sublime Beauty® 3Health News:Influenced by Self-Interest, Humans Less Concerned About Inequity To Others, Researchers Find 2Health News:Influenced by Self-Interest, Humans Less Concerned About Inequity To Others, Researchers Find 3Health News:Best SEO Hosting Suppliers in the Global Market Recommended by Top10BestSEOHosting.com 2
... The American Lung Association of the Upper Midwest shares the ... flooding in several states that we serve. Because flood water ... thousands of people with lung disease, and may cause lung ... these tips. For more specific help on cleaning up after ...
... Globus Medical, Inc., the largest privately held ... the launch of MicroFuse(TM) ST Granules, a unique ... strength and porosity. MicroFuse(TM) technology utilizes proprietary combinations ... manufactured with a patented microsphere process to deliver ...
... medicine to standard therapy made the difference, researchers ... People with cancer of the larynx who ... to keep their larynx than those who received ... study compared treatment with a combination of three ...
... Study finds procedure dramatically reduces transmission of herpes, human ... decision of whether or not to circumcise an infant ... that having the procedure may reduce the risk of ... of more than 5,000 uncircumcised adult Ugandan males, researchers ...
... Bipartisan Group Led by Former Rep. Gephardt Underscores ... Finding Cures for Life-Threatening Diseases , WASHINGTON, March ... applauds President Obama on his support for improving ... costs through continued scientific and technological advancements. (Logo: ...
... of Biology, Geology and Nursing, and Director of the MS ... Islands , was recently awarded a grant of $1,733,406 from ... of their Bridges to Stem Cell Research program. CSUCI was ... program. , , "We are thrilled to have ...
Cached Medicine News:Health News:American Lung Association of Upper Midwest Offers Tips on Dealing With Floodwaters 2Health News:American Lung Association of Upper Midwest Offers Tips on Dealing With Floodwaters 3Health News:Globus Medical's MicroFuse(TM) Technology Engineered for Optimal Strength and Porosity 2Health News:Drug Combo Helps Larynx Cancer Patients Preserve Voice Box 2Health News:Circumcision Guards Against STDs 2Health News:Circumcision Guards Against STDs 3Health News:Council for American Medical Innovation Applauds President Obama for Calling for 'Serious Investments in Science and Technology' 2Health News:CSUCI Receives $1.7 Million Grant for Stem Cell Research Program 2Health News:CSUCI Receives $1.7 Million Grant for Stem Cell Research Program 3
(Date:8/21/2014)... Conn. , Aug. 21, 2014  Aptuit ... West Lafayette, Indiana , has enhanced ... and characterization of small and large molecules, including ... of the Bruker maXisPlus Q-TOF mass spectrometer. ... Goldman , CEO, Aptuit, said, "The expanded large ...
(Date:8/21/2014)... 21, 2014   Memorial Hermann Health System and ... today announced a new partnership to provide a new level ... care centers in the greater Houston ... become the exclusive provider of professional breast radiology services for ... Memorial City, The Woodlands , Northeast, Southwest ...
(Date:8/21/2014)... AUSTIN, Texas , Aug. 21, 2014  Vermillion, ... company focused on gynecologic cancers and women,s health, has ... of Sales and Managed Markets. Ms. Bauzon ... traction and expanding payer coverage for laboratory services companies. ... most recently with PerkinElmer, Inc., where she held the ...
Breaking Medicine Technology:Aptuit SSCI Adds Ultra High Resolution Q-TOF Mass Spectrometer for Large & Small Molecule Analyses 2Memorial Hermann, MD Anderson join forces to provide enhanced breast imaging services throughout the Greater Houston Region 2Memorial Hermann, MD Anderson join forces to provide enhanced breast imaging services throughout the Greater Houston Region 3Memorial Hermann, MD Anderson join forces to provide enhanced breast imaging services throughout the Greater Houston Region 4Vermillion Appoints Holly B. Bauzon as VP of Sales and Managed Markets 2
... 2011 Theramed Corporation ("Theramed") announces that ... Clinical Meeting of the Society of Obstetricians and Gynecologists ... to be used to advance the practice of obstetrics, ... have been approved for sale by Health Canada, and ...
... 14, 2011 Viral Genetics, Inc. (Pinksheets: VRAL) ... company. The Company,s two lead pharmaceutical programs -- ... compounds for drug-resistant cancers -- are being advanced ... New Drug (IND) pathways. An IND application is ...
Cached Medicine Technology:Theramed Corporation to Launch Glenveigh Products, ebb™ and jetty™ at the Society of Obstetricians and Gynecologists of Canada 2Viral Genetics Updates HIV/AIDS and Drug Resistant Cancer Research Programs 2Viral Genetics Updates HIV/AIDS and Drug Resistant Cancer Research Programs 3Viral Genetics Updates HIV/AIDS and Drug Resistant Cancer Research Programs 4
Representing the next step in the evolution of point-of-care testing, the i-STAT 1 Analyzer uses one platform to perform glucose strip testing along with all i-STAT test cartridges....
Lancet cut ultra sharp tip for low penetration resistance. Low noise and impedance level giving you a clear and reliable signal. Stainless steel needle, color coded attached lead wires. Needles sold ...
... Extremely bright xenon ... headlight or other instruments. ... other fiber optic cables. ... certification. Convenient lamp change ...
Provides surgeon's eye view of any procedure. View procedures live or edit tapes or digital files for later use. Extended field-of-vision maintains sharp focus from 8" to 36". Automatic Iris and Gain...
Medicine Products: