Navigation Links
Newer techniques are making cardiac CT safer for children

Coronary computed tomography angiography (CTA) has excellent image quality and diagnostic confidence for the entire spectrum of pediatric patients, with significant reduction of risk with recent technological advancements, according to a study to be presented at the Sixth Annual Scientific Meeting of the Society of Cardiovascular Computed Tomography (SCCT) in Denver, July 14-17.

"Traditionally, pediatric patients who require coronary artery imaging have undergone a cardiac catheterization, which is an invasive procedure with a significant radiation dose, requiring sedation or anesthesia for all patients," explained B. Kelly Han, MD, a pediatric cardiologist at Minneapolis Heart Institute at Abbott Northwestern Hospital and the Children's Heart Clinic and Children's Hospitals and Clinics in Minneapolis. "The newer CT scanners deliver far less radiation than both previous generation CT scanners and catheter based angiography. Also, CTA is non-invasive and has different protocols that can be tailored to decrease the risk for each individual patient."

"One barrier to applying coronary CTA in children has been their relatively high heart rates. Using a combination of medication to slow the heart rate and the new scanner technology, we have been able to obtain excellent images of the coronary arteries in patients as young as five months of age" she said.

Han and colleagues conducted a retrospective review of all coronary CTAs performed on patients less than 18 years of age at Minneapolis Heart Institute from June 2007 through February 2011. The researchers examined the heart rate control with beta blockade, and the radiation dose with the varied scan modes, with the goal of comparing the image quality and the radiation dose.

Patients were separated by scan mode into three groups:

  • Group One: First-generation, dual-source CT scanner with retrospective ECG gating (spiral scan mode);
  • Group Two: Second-generation, dual-source CT scanner with prospective ECG gating (sequential scan mode); and
  • Group Three: Second-generation, dual-source CT using prospective ECG gating with high pitch (flash-scan mode).

The researchers compared the age, heart rate, body surface area, radiation dose estimates and image quality between the three groups. They performed 76 scans in patients from three days to 18 years of age.

The differences in radiation dose between the three scan groups were statistically significant, according to the authors, and high image quality was maintained between groups despite the decreased radiation exposure, Han and colleagues reported. A high percentage of the patients had coronary artery pathology including anomaly, stenosis, or aneurysm. Overall, 17 patients underwent subsequent surgical intervention and surgical findings correlated with coronary CTA in all cases.

"We found that the newer imaging modes decrease the radiation dose between four-fold and seven-fold, without loss in diagnostic accuracy or image quality," Han said. "The estimated radiation dose reduction over traditional angiography is even greater. The aggressive use of beta-blockade to slow the heart rate, in combination with the newer scan modes allows for a very low radiation dose in this young patient population."

This technology also will "significantly decrease" the anesthesia and invasive access risk of coronary imaging, according to Han, as the images are acquired without having to access the heart, and all patients age seven or older did not require sedation.


Contact: Meghan Bethke
Minneapolis Heart Institute Foundation

Related medicine news :

1. Newer Epilepsy Meds Less Likely to Cause Birth Defects: Study
2. Newer Pill Linked to Higher Risk of Blood Clots
3. Newer Versions of the Pill Pose No Added Risk to Gallbladder
4. UCSF analysis shows newer surgery for neck pain may be better
5. Newer antimalarials more effective than quinine against severe malaria
6. Research shows rapid adoption of newer, more expensive prostate cancer treatments
7. Newer Drug May Help Prevent Fracture in Men With Prostate Cancer
8. Newer, more intense chemotherapy with less radiation not more effective against Hodgkins lymphoma
9. Decrease in suicide not linked to newer antidepressants
10. Newer Drugs Beat Gleevec in Head-to-Head Trials
11. In infant heart surgery, newer technique yields better survival in first year of life
Post Your Comments:
(Date:11/27/2015)... ... November 27, 2015 , ... Intellitec Solutions ... SL User Group (MSDSLUG). Recognized as Microsoft’s official group for end users of ... SL software users, partners, industry experts and representatives. Intellitec Solutions’ membership status demonstrates ...
(Date:11/27/2015)... Los Angeles, CA (PRWEB) , ... November 27, 2015 , ... ... the Commission on Accreditation of Allied Health Education Programs (CAAHEP) awarded accreditation to its ... exclusive list of CAAHEP accredited colleges, as only one of twelve colleges and universities ...
(Date:11/27/2015)... ... ... Indosoft Inc., developer and distributor of the world-class Asterisk ... Term Support) into its Q-Suite 5.10 product line. , Making the change to ... of Asterisk that will receive not only security fixes, but feature and bug ...
(Date:11/26/2015)... ... 2015 , ... Somu Sivaramakrishnan announced today that he joined ... offers travelers, value and care based Travel Services, including exclusive pricing on a ... cabin upgrades and special amenities such as, shore excursions, discounted fares, travel gifts ...
(Date:11/26/2015)... Mass. (PRWEB) , ... November 26, 2015 , ... ... thorough second medical opinion process, participated in the 61st annual Employee Benefits Conference. ... Plans and took place Sunday, November 8th through Wednesday, November 11th, 2015. The ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... , November 26, 2015 ... Juntendo universitetssjukhus ser potential att använda SyMRI ... (MR-bilder) för patienter med multipel skleros ... forskningsavtal med SyntheticMR AB för att kunna ... på sjukhuset. Med SyMRI kan man generera ...
(Date:11/26/2015)... India , November 26, 2015 ... --> adds ... Report" and "Investigation Report on China ... and 2021 forecasts data and information ... . ...
(Date:11/26/2015)... 2015 ) ... "Radioimmunoassay Market by Type (Reagents & Kits, ... Clinical Diagnostic Labs), Application (Research, Clinical Diagnostics), ... report to their offering. --> ... of the "Radioimmunoassay Market by Type ...
Breaking Medicine Technology: