Navigation Links
Newer Genetic Info Adds Little to Predicting Breast Cancer
Date:3/17/2010

r and nearly 6,000 were healthy controls.

The question, Hartge said, was simple: "Does getting your SNPs measured really help with prediction, beyond the simple question of the Gail model?"

After evaluating the data, "we found that it helped some," Hartge said.

To quantify how much exactly is difficult, she said, but to put it in other words: "Our data showed that women in the top 20 percent of risk score from the Gail model alone would comprise about 29.9 percent of the actual breast cancer cases. Our data also show that women in the top 20 percent of risk score from the Gail-Plus-SNPs model would comprise about 33.6 percent of the actual breast cancer cases. So you see adding the SNPs helps some."

But for a model to be considered highly effective, women who score in the top 20 percent of risk would have at account for 80 percent of the women who actually ended up with breast cancer, Hartge said.

The study shows that, by that yardstick, the new risk-assessment model just isn't there yet.

In the future, Hartge said, as more discoveries about genetic variants are made, they can be incorporated into the risk model, hopefully increasing the accuracy of the prediction.

But for now, "based on our current data, we do not recommend that women seek genotyping as a means of better understanding their risk profile," Hartge said.

Doctors use the Gail model to determine risk and sometimes advise women about preventive measures such as the frequency of mammograms.

In an editorial accompanying the report, Dutch researchers took a "stay tuned" stance.

"For women seeking advice on their personal risk of breast cancer, it is obviously too early to incorporate SNP testing into a counseling procedures, although such tests are already advertised for this purpose on the internet," they wrote.

Like Hartge, however, the editorial authors -- Dr. Peter Devilee of Leiden Universi
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Newer antidepressants led to less, not more, teen suicides
2. Newer Antibiotic Speeds TB Healing
3. Newer radiation treatment easier for some throat cancer patients
4. Newer Anticlotting Drug Safe, Effective for Heart Surgeries
5. Newer Sedative Might Help Patients on Ventilators
6. Newer Rheumatoid Arthritis Drugs Lower Production of B Cells
7. Newer Prostate Cancer Treatment Similar to Traditional Surgery
8. Newer Blood Pressure Drug No Better Than Placebo in Preventing Stroke
9. Newer Blood Pressure Drug Better for Some Heart Patients, Diabetics
10. First generation antipsychotic drugs as effective as newer ones in some children
11. Newer antipsychotics no better than older drug in treating child and adolescent schizophrenia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/2/2015)... 2015 Gummy smile reduction expert, ... reshaping can involve one or several procedures to reduce the ... tissue for a more even gum line. Dr. Farnoosh is ... that can permanently lighten discolored or naturally dark gums. ... involves a personalized treatment plan to address a patient’s specific ...
(Date:3/2/2015)... Burns Engineering's Lab-to-Lab Calibration Service offers ... Platinum Resistance Thermometers (SSPRTs) and industrial Resistance Temperature ... . . . guaranteed. Their metrology ... 200706-0), ISO 9001 and 17025 Certified and provides ... to 500°C, both ITS-90 and Callendar-van Dusen calibrations ...
(Date:3/2/2015)... Over the last five years the ultrasound ... to expand their geographic presence and achieve economies of ... $6.2 billion by 2019 at CAGR of 5.1% from ... and Canada and a major part of Europe are ... as Asia-Pacific including China and India, Latin America and ...
(Date:3/2/2015)... This year, the National Multiple Sclerosis Society’s annual awareness ... people across the country to unite, raise awareness, ... their best lives. MS Awareness Week is a special week ... the Society’s vision of a world free of MS. ... the central nervous system, interrupts the flow of information within ...
(Date:3/2/2015)... 02, 2015 Atlantic Information Services, Inc. ... AIS’s Directory of Health Plans: 2015 , the all-new ... the U.S. health plan market, with enrollment data and ... States. , Available as a printed book containing ... trends in quick-view tables and charts, as well as ...
Breaking Medicine News(10 mins):Health News:Gummy Smile Expert, Dr. Alex Farnoosh, is Now Offering Gum Reshaping Procedures 2Health News:Burns Engineering Announces Quick-Turn Temperature Calibrations 2Health News:Therapeutic Ultrasound Devices Market worth $6.2 Billion by 2019 - New Research Report by MarketsandMarkets 2Health News:Therapeutic Ultrasound Devices Market worth $6.2 Billion by 2019 - New Research Report by MarketsandMarkets 3Health News:Every Connection Counts During MS Awareness Week 2Health News:Every Connection Counts During MS Awareness Week 3Health News:Every Connection Counts During MS Awareness Week 4Health News:Now Available from AIS: 12th Edition of Annual Book Containing Health Plan Enrollment Data, Contact Information 2
... 21 Secretary of Veterans,Affairs Dr. James B. Peake ... panels that will make recommendations on ways the Department,of ... prevention,suicide research and suicide education., "There is nothing ... one of,the great men or women who have served ...
... 1 Day ASV Single Vision Lens Now Available Through Licensed Eye Care ... ... Inc. (OTC,Bulletin Board: UVICF; TSX Venture Exchange: UVI), which develops,licenses, manufactures, distributes ... C-VUE(R) 1 Day ASV, which is the,first aspheric, daily disposable contact lens ...
... Leading Pennsylvania Health Insurer Reduce ... DST Health Solutions,today announced an extension of ... health insurer serving nearly 3.4 million,members, for business ... center in Harrisburg, Pa. will,continue to provide business ...
... the Most Promising ... Driving the Future of Technology, SUNNYVALE, Calif., May ... technology in enterprise mobility,today announced that it has won ... most innovative private technology companies based in North,America., ...
... young flight attendant,complains of swelling and tightness in ... her from exercising. Will the ultrasound results indicate,deep ... symptomatology and the frequent presence of comorbidities,make it ... primary care,practice. The Journal of Family Practice has ...
... Thoracic Societys 2008 International Conference in Toronto on Wednesday, May ... young adults. One links low levels of a protein called ... in young women. A second finds that high levels of ... , The data from both studies comes from the ...
Cached Medicine News:Health News:VA Secretary Appoints Panel of National Suicide Experts 2Health News:Unilens Launches Aspheric C-VUE(R) Daily Disposable Lens 2Health News:DST Health Solutions and Independence Blue Cross Extend Business Process Outsourcing Agreement 2Health News:DST Health Solutions and Independence Blue Cross Extend Business Process Outsourcing Agreement 3Health News:Agito Networks Wins Red Herring North America 100 Award Out of More Than 800 Companies 2Health News:Agito Networks Wins Red Herring North America 100 Award Out of More Than 800 Companies 3Health News:CME Publication Gives Clinicians a Leg Up in Treating Disorders of the Lower Extremities 2Health News:Studies provide insights into lung disease and lung function in young adults 2Health News:Studies provide insights into lung disease and lung function in young adults 3
(Date:3/2/2015)... 2, 2015   Emerson Ecologics, LLC ... supplements, prescription products and natural health and ... with Anabolic Laboratories, a leading manufacturer of ... new partnership will allow Anabolic Laboratories to ... practitioner segments and provide customers with added ...
(Date:3/2/2015)... BUENA, N.J., March 2, 2015  IGI Laboratories, Inc. (NYSE ... announced its financial results for the fourth quarter and year ... to Date 2014 Highlights , Total revenues of ... of 104% over the same quarter in 2013 , ... 31, 2014, an increase of 85% over the same period ...
(Date:3/2/2015)... March 2, 2015 Halozyme Therapeutics, Inc. (NASDAQ: ... and full year ended December 31, 2014. Financial highlights for ... net loss of $5.3 million, or $0.04 per share. This ... of $22.0 million, or $0.19 per share, for the fourth ... include revenues of $75.3 million and a net loss of ...
Breaking Medicine Technology:Anabolic Laboratories Selects Emerson Ecologics As Distribution Partner 2Anabolic Laboratories Selects Emerson Ecologics As Distribution Partner 3IGI Laboratories Announces Fourth Quarter And Year End 2014 Results 2IGI Laboratories Announces Fourth Quarter And Year End 2014 Results 3IGI Laboratories Announces Fourth Quarter And Year End 2014 Results 4IGI Laboratories Announces Fourth Quarter And Year End 2014 Results 5IGI Laboratories Announces Fourth Quarter And Year End 2014 Results 6IGI Laboratories Announces Fourth Quarter And Year End 2014 Results 7IGI Laboratories Announces Fourth Quarter And Year End 2014 Results 8IGI Laboratories Announces Fourth Quarter And Year End 2014 Results 9IGI Laboratories Announces Fourth Quarter And Year End 2014 Results 10IGI Laboratories Announces Fourth Quarter And Year End 2014 Results 11IGI Laboratories Announces Fourth Quarter And Year End 2014 Results 12Halozyme Reports Fourth Quarter And Full Year 2014 Financial Results 2Halozyme Reports Fourth Quarter And Full Year 2014 Financial Results 3Halozyme Reports Fourth Quarter And Full Year 2014 Financial Results 4Halozyme Reports Fourth Quarter And Full Year 2014 Financial Results 5Halozyme Reports Fourth Quarter And Full Year 2014 Financial Results 6Halozyme Reports Fourth Quarter And Full Year 2014 Financial Results 7Halozyme Reports Fourth Quarter And Full Year 2014 Financial Results 8Halozyme Reports Fourth Quarter And Full Year 2014 Financial Results 9
... Mass., Aug. 26 Sermo ... physicians, today announced a free Sermo Report titled, " ... covers physician opinions about the introduction of an investigational ... to the results, 46% of physicians feel that ticagrelor ...
... Cardioxyl Pharmaceuticals, Inc. , a clinical-stage pharmaceutical ... disease, today announced that it has initiated a dose-defining ... for the treatment of patients with acute decompensated heart ... at the time of discharge from U.S. hospitals and ...
Cached Medicine Technology:Sermo Report Indicates that Ticagrelor is Likely to Affect the Standard of Care for ACS Patients 2Cardioxyl Pharmaceuticals Initiates Dose-Defining Phase IIa Study of Its Lead Candidate, CXL-1020, in Heart Failure Patients 2Cardioxyl Pharmaceuticals Initiates Dose-Defining Phase IIa Study of Its Lead Candidate, CXL-1020, in Heart Failure Patients 3Cardioxyl Pharmaceuticals Initiates Dose-Defining Phase IIa Study of Its Lead Candidate, CXL-1020, in Heart Failure Patients 4
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: