Navigation Links
Newer Drugs Beat Gleevec in Head-to-Head Trials
Date:6/5/2010

More chronic myeloid leukemia patients responded to Sprycel and Tasigna than Gleevec

SATURDAY, June 5 (HealthDay News) -- Two new drugs, dasatinib (Sprycel) and nilotinib (Tasigna), appear better than imatinib (Gleevec) in treating patients with newly diagnosed chronic myeloid leukemia and should be considered as first-line treatments, two new studies show.

The findings, which should change clinical practice, are to be presented Saturday at the American Society of Clinical Oncology annual meeting in Chicago and were simultaneously published online June 5 in the New England Journal of Medicine.

"Both next-generation inhibitors of BCR-ABL [dasatinib and nilotinib] are superior to Gleevec in treating chronic myeloid leukemia when compared head-to-head after one year of follow-up," said Dr. Charles L. Sawyers, chair of the Human Oncology and Pathogenesis Program at the Howard Hughes Medical Institute at Memorial Sloan-Kettering Cancer Center in New York City and author of an accompanying journal editorial.

"This magnitude of success -- beating a drug like imatinib [Gleevec] that was already pretty great -- is possible because we have a very precise understanding of the drug target BCR-ABL and of the mechanisms of resistance to imatinib," Sawyers added.

Newly diagnosed chronic myeloid leukemia patients should probably now be treated with one of the new drugs instead of imatinib, he noted.

In the first study, a team led by Dr. Hagop Kantarjian, chairman of the leukemia department at the University of Texas M.D. Anderson Cancer Center in Houston, randomly assigned 519 patients to Sprycel or Gleevec.

After a year, 77 percent of the patients receiving Sprycel had a complete cytogenetic response, compared with 66 percent of the patients receiving Gleevec, the researchers found.

Complete cytogenetic response is the disappearance of all the cancer cells from the bone marrow, Kanta
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1 2 3 4

Related medicine news :

1. Development of Newer Therapies to Treat Lifestyle Disorders and Reduce the Risk of Co-morbidities is Key to the Expansion of the European Lifestyle Disorders Therapeutics Market, Says Frost & Sullivan
2. Newer Drug More Effective in Psoriasis Treatment
3. Newer cornea transplant surgery shows short- and long-term promise
4. Newer Blood Test Predicts Diabetes, Heart Disease
5. Newer Genetic Test for Autism More Effective
6. Newer Blood Thinner Beats Plavix for Bypass Patients
7. Newer Genetic Info Adds Little to Predicting Breast Cancer
8. In infant heart surgery, newer technique yields better survival in first year of life
9. New Drugs, New Combinations Fight Breast Cancer
10. NICE guidelines ration affordable osteoporosis drugs
11. Bone Drugs May Beat Back Breast Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/19/2015)... 2015 Autocarinsurancecheap.com has released a new ... offer financial protection for vulnerable family members. , ... insured dies or is disabled in an accident. The ... bought with an auto insurance plan. However, AD&D insurance ... to a life insurance policy. The newly blog post ...
(Date:4/19/2015)... (PRWEB) April 19, 2015 Carinsurancehints.com has released ... who have to claim auto insurance benefits . ... pictures and gather all the necessary information for claiming auto ... a good insurance plan to cover most of the damages. ... insurance benefits for an accident. , Drivers can compare ...
(Date:4/19/2015)... April 19, 2015 Insurancecarsinsurance.com has released ... months and explaining how bad weather can affect ... have a big impact on auto insurance premiums. In ... auto insurance prices are higher than in other parts. ... will be during the next several months and what ...
(Date:4/19/2015)... A live auction will be held to ... hospital in Brooklyn, NY and other national consignors. Various types ... anesthesia, exam and much more. , The auction will ... at 9:00am CDT each day. The equipment is at their ... IL 60160. Anyone can participate in the auction including ...
(Date:4/19/2015)... MA (PRWEB) April 19, 2015 Family and ... Bowling for Brains in Memory of Brad Baddeley event ... Brain Aneurysm Foundation. , Bowling for Brains is cheduled to ... located 4700 Dudley Street in Lincoln, Nebraska. Participants may arrive ... 1:00 to 3:00pm. , The cost is only $4 per ...
Breaking Medicine News(10 mins):Health News:Accidental Death and Dismemberment Insurance Can Provide Financial Security! 2Health News:An Online Guide About Claiming Auto Insurance Benefits After an Accident 2Health News:Bad Weather Can Cause Accidents and Affect Auto Insurance Prices! 2Health News:Centurion to Sell Surplus Medical Equipment in Online and On-Site Auction 2Health News:Lincoln, NE’s Bowling for Brains to benefit Renowned Brain Aneurysm Foundation 2Health News:Lincoln, NE’s Bowling for Brains to benefit Renowned Brain Aneurysm Foundation 3
... Network, the prominent advocacy group launches the inaugural World ... site, www.worldmrsaday.org . MRSA activists ... and the community for a greater response to the ... alarming rate.MRSA Survivors Network, the official organization for World ...
... 5 The World Health Organization says a Swine ... already declared emergencies. Many experts believe the Federal government ... the outbreak takes on the public will become increasing ... of panic. Your only defense: to prepare your department ...
... Give Voice to Improving Quality Care and Quality Careers , ... for better senior living, celebrates National Nurse Week May 6-12, ... how to improve the business, the quality of care and ... Vigilan is offering an online and phone-based survey where ...
... Indiana University School of Medicine , the not-for-profit Taking Control ... for people living with diabetes on May 30 from 9 ... The TCOYD conference, lunch and health fair brings national and ... types of diabetes, those at risk for diabetes, and their ...
... Society of Cellular Therapy (ISCT) Demonstrating Potential to ... in TransplantationOLDSMAR, Fla., May 5 /PRNewswire-FirstCall/ -- ... new study showing that adding menstrual blood stem ... blood expands the number of progenitor cells (cells ...
... Inc. (Nasdaq: CYNO ), a ... light-based aesthetic treatment systems, today announced financial results for ... 2009 Financial Results , Consistent with Cynosure,s ... March 31, 2009 were $14.8 million, reflecting the continued ...
Cached Medicine News:Health News:MRSA Activists Rally For World MRSA Day 2Health News:Ready or Not - Flu Pandemic Has Arrived 2Health News:Vigilan Honors National Nurse Week in Assisted Living, Independent Living and Dementia Care 2Health News:Taking Control of Your Diabetes Conference Returns to Indianapolis to Bring Answers, Advocacy and Hope for People With Diabetes 2Health News:Taking Control of Your Diabetes Conference Returns to Indianapolis to Bring Answers, Advocacy and Hope for People With Diabetes 3Health News:Menstrual Blood Stem Cells May Significantly Increase Yield of Cord Blood Stem Cells 2Health News:Menstrual Blood Stem Cells May Significantly Increase Yield of Cord Blood Stem Cells 3Health News:Menstrual Blood Stem Cells May Significantly Increase Yield of Cord Blood Stem Cells 4Health News:Menstrual Blood Stem Cells May Significantly Increase Yield of Cord Blood Stem Cells 5Health News:Cynosure Reports Financial Results for the First Quarter of 2009 2Health News:Cynosure Reports Financial Results for the First Quarter of 2009 3Health News:Cynosure Reports Financial Results for the First Quarter of 2009 4Health News:Cynosure Reports Financial Results for the First Quarter of 2009 5Health News:Cynosure Reports Financial Results for the First Quarter of 2009 6Health News:Cynosure Reports Financial Results for the First Quarter of 2009 7Health News:Cynosure Reports Financial Results for the First Quarter of 2009 8Health News:Cynosure Reports Financial Results for the First Quarter of 2009 9Health News:Cynosure Reports Financial Results for the First Quarter of 2009 10
(Date:4/17/2015)... DUBLIN , Apr. 17, 2015 Research and ... addition of the "Medical Oxygen Systems - Global ... This report analyzes the worldwide markets for Medical ... Oxygen Concentrators, Liquid Oxygen Systems, Oxygen Cylinders & Regulators, ... analytics for the US, Canada , ...
(Date:4/17/2015)... 2015 Today, the Pharmaceutical Research and ... 12 biopharmaceutical companies as "We Work For Health ... and community service. Established in 2009, ... created by the biopharmaceutical industry to honor employees ... but have also shown an outstanding commitment to ...
(Date:4/17/2015)... Apr. 16, 2015 Research and Markets ... of the "The Corporate Reputation of Pharma ... Edition " report to their offering. ... Perspective, is now in its fourth edition. This ... early 2015). For each annual Corporate Reputation report, ...
Breaking Medicine Technology:Medical Oxygen Systems - 2015 Global Strategic Business Report Featuring Leading Players, Caire, Invacare & Philips Respironics 2PhRMA Applauds 2015 We Work For Health Champion Award Winners 2PhRMA Applauds 2015 We Work For Health Champion Award Winners 3The Corporate Reputation of Pharma - The Global Patient Perspective in 2014 2
... April 18, 2012 SurgLine International, Inc. (SGLN.PK) ... ("SurgLine") reported that the company has successfully completed its ... owned surgery center in the state of Indiana. The ... substantial savings over the competition. Toland ...
... Scripps Research Institute have shown that an injectable solution can ... findings could lead to human clinical trials of a treatment ... emergency. Cocaine is involved in more than 400,000 emergency-room visits ... States. The findings, reported recently in the journal ...
Cached Medicine Technology:SurgLine International, Inc. Update On New Revenues 2Scripps Research Institute Scientists Develop Antidote for Cocaine Overdose 2Scripps Research Institute Scientists Develop Antidote for Cocaine Overdose 3Scripps Research Institute Scientists Develop Antidote for Cocaine Overdose 4
2.5 mm x 4 mm opening. Hexagonal handle....
Double-ended. Designated most popular model or size....
Double-ended. Sharp and blunt 6.5 mm tips. Designated most popular model or size....
2 mm tip....
Medicine Products: