Navigation Links
Newer Drug-Releasing Stent Cuts Chances of Cardiac Events: Study
Date:8/21/2012

TUESDAY, Aug. 21 (HealthDay News) -- A newer generation, drug-releasing stent led to fewer adverse cardiac events, such as heart-related death or heart attack linked to the same artery, than bare metal stents did among heart attack patients, a new study shows.

Stents are tiny mesh tubes surgically implanted to open arteries.

Swiss researchers noted the newer drug-emitting stents may also help patients avoid the chronic inflammation associated with early-generation drug-releasing stents.

"Newer-generation drug-eluting stents with biodegradable polymers provide controlled drug release," the study authors explained in the Aug. 22/29 issue of the Journal of the American Medical Association.

Led by Dr. Lorenz Raber, of Bern University Hospital, the research team compared the safety and effectiveness of stents that released the drug biolimus from a biodegradable polymer, against bare metal stents that did not release a drug.

The study involved almost 1,200 patients in Europe and Israel who had a type of heart attack known as ST-segment elevation myocardial infarction (STEMI). Nearly 80 percent of the patients were men, and the average age was 61 years.

The participants were randomly assigned to receive the drug-releasing stent or the bare metal stent. They were examined one month after their artery opening procedure, and again at 12 months. The researchers determined the effectiveness of the stents by measuring rates of adverse cardiac events, including cardiac death and other heart problems.

The investigators found that at one year, 4.3 percent of patients who received the drug-releasing stents experienced major adverse cardiac events, compared to 8.7 percent of patients who received bare metal stents.

These findings represent a significant 4.4 percent absolute reduction and 51 percent relative reduction in the risk for major adverse cardiac events, the researchers pointed out in a journal news release.

Use of the new drug-releasing stent also resulted in reduced risk for cardiac death. At one year, rates of clotting within the stent were about 1 percent among patients with the drug-releasing stents, compared to just over 2 percent among patients who received bare metal stents.

"Our results suggest better clinical outcomes in terms of major adverse cardiac events of a stent releasing biolimus from a biodegradable polymer compared with a bare metal stent for the treatment of patients with STEMI," the study authors concluded.

Another expert agreed.

"Newer generation drug-eluting stents which are currently FDA-approved in the United States have been shown to be superior to bare metal stents in decreasing event rates at one year when used for [heart attack]," said Dr. Barry Kaplan, vice chairman of cardiology at North Shore University Hospital in Manhasset, N.Y. "This trial is further proof that drug-eluting stents used in heart attack patients lead to superior results," he added.

And Kaplan noted that, compared to bare metal stents, the drug-releasing models had fewer dangerous events at one year, including re-closure of the artery or clotting within the stent.

But, he added one caveat.

"The relative comparison between the biolimus-coated stent used in this study versus [other] currently available second-generation drug-eluting stents [available in the United States] still needs to be determined," Kaplan said.

More information

The U.S. National Library of Medicine has more about stents.

-- Mary Elizabeth Dallas

SOURCES: Barry Kaplan, M.D., F.A.C.C., vice chairman, cardiology, North Shore University Hospital, Manhasset, N.Y., and Long Island Jewish Medical Center, New Hyde Park, N.Y.; Journal of the American Medical Association, news release, Aug. 21, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Newer Antidepressants May Be Safe for Parkinsons Patients
2. Newer Second-Line Diabetes Drug May Outperform Older Meds
3. Law Firm Aggressively Litigating against Birth Control Makers for their Newer, but Allegedly Unsafer Products: Nuvaring, Yaz, BeYaz, Yasmin, Ocella, Gianvi
4. Newer technology to control blood sugar works better than conventional methods
5. Newer hip reconstruction technique provides good outcomes for athletes
6. Newer Bone Drug Better for Advanced Breast Cancer Patients: Study
7. Older Antipsychotics May Work as Well as Newer Ones: Review
8. Newer Psoriasis Drugs May Lower Heart Attack Risk for Patients
9. Dissolvable Heart Artery Stents Appear Safe in Study
10. Life-saving primary PCI rising in Stent for Life countries
11. Baseline characteristics of children with mild persistent asthma predict response to ICS
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Newer Drug-Releasing Stent Cuts Chances of Cardiac Events: Study
(Date:10/13/2017)... ... ... Lori R. Somekh, founder of the Law Office of Somekh & ... and special needs planning attorneys. “Membership in ElderCounsel helps our office remain up to ... with elder law attorneys nationwide,” said Somekh. , ElderCounsel was founded ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Many families have ... many long-term care insurance companies have a waiver for care if the client has ... period, when the family pays for care, is often waived, so the benefits from ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network ... advocate for action towards gender equality at their inaugural Summit in New York City ... and reached a social audience of over 3 million. To watch the Mobilize Women ...
(Date:10/13/2017)... Abilene, Texas (PRWEB) , ... October 13, 2017 , ... ... publication this week that explains one of the most popular and least understood books ... seems like cryptic and puzzling descriptions that have baffled scholars for centuries. Many have ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, ... Development, has been awarded a contract by the Center for Medicare and Medicaid ... to accelerate the enterprise use of Agile methodologies in a consistent and high ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... Oct. 11, 2017  True Health, a leader ... its effort during National Breast Cancer Awareness month ... risks. Research ... calculated that more than 10 million American women ... in BRCA1 or BRCA2 and have not had testing. ...
(Date:10/10/2017)... 10, 2017  NDS received FDA 510(k) clearance in May 2017 ... display stand specifically designed for endoscopy environments. An innovative secondary monitor ... clinical solution to support the improvement of patient outcomes, procedural efficiency, ... ... ...
(Date:10/7/2017)... Texas , Oct. 6, 2017   Provista, ... with more than $100 billion in purchasing power, today ... news and information. The Newsroom is the ... and industry trends, infographics, expert bios, news releases, slideshows ... having access to a wealth of resources at their ...
Breaking Medicine Technology: