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Newer Contraceptive Pills Could Raise Clot Risk, FDA Warns
Date:9/26/2011

continue use without talking to their health care provider because they may not need to come off the pill at all. However, newcomers to the pill might consider older options.

"The question is, should patients who have been on it for years, should they switch? I think they should talk to their doctors," said Dr. Jennifer Wu, an obstetrician/gynecologist at Lenox Hill Hospital in New York City. "[And] I would not start patients on this pill. Blood clots are very serious. They can kill patients. With all the options we have, we should probably start [new patients] with safer contraceptive pills."

Women with other additional risk factors for blood clots definitely should not be on drospirenone-containing pills, Wu added.

Risk factors for VTE include smoking, being overweight or a family history of blood clots.

The FDA statement released Monday noted that studies to date have only looked at pills containing drospirenone and a higher dose of estrogen, not those containing drospirenone and a lower dose of estrogen. So, it's possible that some drospirenone-containing products may be safer than others.

This isn't likely to be the last word on the matter, either: FDA advisory committees are scheduled to delve further into the matter at a December meeting, at which time the full findings of the agency-funded study will be released.

More information

Find out more on this issue at the U.S. Food and Drug Administration.

SOURCES: Jennifer Wu, M.D., obstetrician/gynecologist, Lenox Hill Hospital, New York City; U.S. Food and Drug Administration, news release, Sept. 26, 2011


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