Navigation Links
Newer Antipsychotics May Boost Weight in Alzheimer's Patients
Date:4/15/2009

Drugs such as olanzapine, quetiapine may also lower 'good' cholesterol, researchers say

WEDNESDAY, April 15 (HealthDay News) Newer antipsychotic drugs promote weight gain and lower levels of HDL ("good") cholesterol in Alzheimer's patients, according to a new study of more than 400 elderly patients.

The drugs, olanzapine and quetiapine, were both associated with significant weight gain. In addition, patients who took olanzapine experienced increases in waist circumference and declines in HDL cholesterol.

The longer patients took the drugs, the more likely they were to experience significant weight gain. However, the weight gain occurred in women but not in men. Another drug, risperidone, wasn't associated with harmful metabolic changes, according to findings from the Clinical Antipsychotic Trials of Intervention Effectiveness -- Alzheimer's Disease (CATIE-AD) study, funded by the U.S. National Institute of Mental Health.

The study was to be published online April 15 in the American Journal of Psychiatry.

"These findings are especially troubling, because antipsychotics are associated with a higher risk of death and cerebrovascular adverse events in patients with dementia. They're often used to minimize disruptive symptoms (such as psychosis or agitation), but patients should be monitored more closely," principal investigator Dr. Lon S. Schneider said in an American Psychiatric Association news release.

These kinds of metabolic side effects have been noted in schizophrenia patients who take second-generation antipsychotic drugs, experts said.

More information

The Alzheimer's Association has more about standard treatments for Alzheimer's disease.



-- Robert Preidt



SOURCE: American Psychiatric Association, news release, April 15, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Newer antidepressants led to less, not more, teen suicides
2. Newer Antibiotic Speeds TB Healing
3. Newer radiation treatment easier for some throat cancer patients
4. Newer Anticlotting Drug Safe, Effective for Heart Surgeries
5. Newer Sedative Might Help Patients on Ventilators
6. Newer Rheumatoid Arthritis Drugs Lower Production of B Cells
7. Newer Prostate Cancer Treatment Similar to Traditional Surgery
8. Newer Blood Pressure Drug No Better Than Placebo in Preventing Stroke
9. Newer Blood Pressure Drug Better for Some Heart Patients, Diabetics
10. First generation antipsychotic drugs as effective as newer ones in some children
11. Newer antipsychotics no better than older drug in treating child and adolescent schizophrenia
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Newer Antipsychotics May Boost Weight in Alzheimer's Patients
(Date:6/24/2016)... Marne, Michigan (PRWEB) , ... June 24, 2016 , ... ... To deal with these feelings, many turn to unhealthy avenues, such as drug or ... Center of Marne, Michigan, has released tools for healthy coping following a traumatic event. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, ... at his family verbally and physically. , “When something upset him, he couldn’t control his ... it. He would throw rocks at my other children and say he was going to ...
(Date:6/24/2016)... ... 24, 2016 , ... Global law firm Greenberg Traurig, P.A. announced that 20 ... by their peers for this recognition are considered among the top 2 percent of ... honors as members of this year’s Legal Elite Hall of Fame: Miami Shareholders ...
(Date:6/24/2016)... Diego, CA (PRWEB) , ... June 24, 2016 , ... ... with the American Cancer Society and the Road To Recovery® program to drive cancer ... to seniors and other adults to ensure the highest quality of life and ongoing ...
(Date:6/24/2016)... , ... June 24, 2016 , ... People across the ... Genome magazine’s Code Talker Award, an essay contest in which patients and their families ... to be presented at the 2016 National Society of Genetic Counselors (NSGC) Annual Education ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... INDIANAPOLIS , June 23, 2016 Roche ... received 510(k) clearance for its Elecsys BRAHMS PCT (procalcitonin) ... severe sepsis or septic shock. With this clearance, Roche ... provide a fully integrated solution for sepsis risk assessment ... associated with bacterial infection and PCT levels in blood ...
(Date:6/23/2016)... , June 23, 2016 ... CAPR ), a biotechnology company focused on the ... announced that patient enrollment in its ongoing randomized ... has exceeded 50% of its 24-patient target. Capricor ... the third quarter of 2016, and to report ...
(Date:6/23/2016)... Pa. , June 23, 2016 Bracket ... will launch its next generation clinical outcomes platform, Bracket eCOA ... Meeting held on June 26 – 30, 2016 in ... the first electronic Clinical Outcome Assessment product of its kind ... Booth #715. Bracket eCOA 6.0 is a flexible ...
Breaking Medicine Technology: