Navigation Links
Newer Antipsychotics May Boost Weight in Alzheimer's Patients
Date:4/15/2009

Drugs such as olanzapine, quetiapine may also lower 'good' cholesterol, researchers say

WEDNESDAY, April 15 (HealthDay News) Newer antipsychotic drugs promote weight gain and lower levels of HDL ("good") cholesterol in Alzheimer's patients, according to a new study of more than 400 elderly patients.

The drugs, olanzapine and quetiapine, were both associated with significant weight gain. In addition, patients who took olanzapine experienced increases in waist circumference and declines in HDL cholesterol.

The longer patients took the drugs, the more likely they were to experience significant weight gain. However, the weight gain occurred in women but not in men. Another drug, risperidone, wasn't associated with harmful metabolic changes, according to findings from the Clinical Antipsychotic Trials of Intervention Effectiveness -- Alzheimer's Disease (CATIE-AD) study, funded by the U.S. National Institute of Mental Health.

The study was to be published online April 15 in the American Journal of Psychiatry.

"These findings are especially troubling, because antipsychotics are associated with a higher risk of death and cerebrovascular adverse events in patients with dementia. They're often used to minimize disruptive symptoms (such as psychosis or agitation), but patients should be monitored more closely," principal investigator Dr. Lon S. Schneider said in an American Psychiatric Association news release.

These kinds of metabolic side effects have been noted in schizophrenia patients who take second-generation antipsychotic drugs, experts said.

More information

The Alzheimer's Association has more about standard treatments for Alzheimer's disease.



-- Robert Preidt



SOURCE: American Psychiatric Association, news release, April 15, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Newer antidepressants led to less, not more, teen suicides
2. Newer Antibiotic Speeds TB Healing
3. Newer radiation treatment easier for some throat cancer patients
4. Newer Anticlotting Drug Safe, Effective for Heart Surgeries
5. Newer Sedative Might Help Patients on Ventilators
6. Newer Rheumatoid Arthritis Drugs Lower Production of B Cells
7. Newer Prostate Cancer Treatment Similar to Traditional Surgery
8. Newer Blood Pressure Drug No Better Than Placebo in Preventing Stroke
9. Newer Blood Pressure Drug Better for Some Heart Patients, Diabetics
10. First generation antipsychotic drugs as effective as newer ones in some children
11. Newer antipsychotics no better than older drug in treating child and adolescent schizophrenia
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Newer Antipsychotics May Boost Weight in Alzheimer's Patients
(Date:2/5/2016)... ... February 05, 2016 , ... ... the company's lighter, sleeker next generation LYNX VR Indoor Trainer with multi-rider capability ... in design and manufacturing not only reduce the weight of the unit, they ...
(Date:2/5/2016)... ... February 05, 2016 , ... The event is being ... Block Event Center in Minneapolis, Minn. Triumph Over Parkinson’s will fund nearly $100,000 for ... of Schneiderman’s Furniture, lives with Parkinson’s disease and is the architect of this informative ...
(Date:2/5/2016)... , ... February 05, 2016 , ... Looking for a ... be at the tips of your toes. Foot massage, whether administered by a professional ... comfort and relaxation. The American Board of Multiple Specialties in Podiatry (ABMSP) ...
(Date:2/5/2016)... ... 05, 2016 , ... The Lymphoma Research Foundation (LRF) – ... serving the lymphoma community through a comprehensive series of education programs, outreach initiatives ... Tasting Event at the La Gorce Country Club in Miami Beach on March ...
(Date:2/5/2016)... ... 2016 , ... The American public tends to feel uncomfortable about drinking recycled ... municipal or well water. The recent experience with lead contaminated water in Flint, Michigan, ... way toward increasing public acceptance of recycled waste water as drinking water. , ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... , Feb. 5, 2016  Redwood Scientific Technologies, Inc. ... product designed to help women balance their hormones. This ... technology. Jason Cardiff , President and ... able to help the millions of women across the ... effects of imbalanced hormones. Our research and development team ...
(Date:2/5/2016)... Ontario , Feb. 5, 2016  Aralez Pharmaceuticals ... combination of POZEN Inc. ("POZEN") and Tribute Pharmaceuticals Canada Inc. ... POZEN and shareholders of Tribute. The combined company will ... pharmaceutical company with operations in Canada ... the United States . Under the terms of ...
(Date:2/5/2016)... -- Dehaier Medical Systems Ltd. (Nasdaq: DHRM ... markets and sells medical devices and wearable sleep ... and international markets, today announced its corporate and ... Company,s resources to develop its mobile health business, ... more on its major businesses. As of this ...
Breaking Medicine Technology: