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New ways to protect female fertility
Date:9/21/2012

did the cells survive being irradiated, they were able to repair the DNA damage they had sustained and could be ovulated and fertilised, producing healthy offspring. When the cells were also missing the NOXA protein, there was even better protection against radiation."

Future treatments could block the function of PUMA, preventing egg cell death in patients undergoing chemotherapy or radiation.

Professor Jock Findlay, head of the Female Reproductive Biology Group at PHI, said the study could also have implications for delaying menopause.

"We know that the timing of menopause is influenced by how many egg cells a female has," he said. "Interventions that slow the loss of egg cells from the ovaries could delay premature menopause, prolonging female fertility, such a treatment could have the potential to reduce menopause-associated health conditions, such as osteoporosis and heart disease."


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Contact: Emily Walker
emily.walker@monash.edu
61-399-034-844
Monash University
Source:Eurekalert

Page: 1 2

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