Navigation Links
New view of origins of eye diseases

Using new technology and new approaches, researchers at Lund University in Sweden hope to be able to explain why people suffer vision loss in eye diseases such as retinal detachment and glaucoma.

Research on diseases of the eye such as retinal detachment and glaucoma has until now focused on the biochemical process that takes place in the eye in connection with the diseases.

Fredrik Ghosh and Linna Taylor have concentrated instead on attempting to understand what happens on a biomechanical level in the diseases and have produced results that have drawn a lot of interest from experts.

"We have not previously understood the mechanisms behind glaucoma and retinal detachment, but we knew that these diseases had a strong mechanical component. Our findings could form an initial explanation as to why we develop these diseases", said eye researchers Fredrik Ghosh and Linna Taylor.

Using new technology, the eye researchers at the Department of Clinical Sciences in Lund, in collaboration with researchers at the Department of Biology at Lund University, have developed a method to investigate the importance of the biomechanical environment within the central nervous system.

For their studies, they grow retinal tissue from adult pigs in a stretched state similar to the normal mechanical state present in the living eye. Compared with unstretched tissue, which in cultures dies after a few days when the retina's mechanical balance is disturbed, studies can now be performed for up to ten days in retina with a well-preserved structure and significantly higher cell survival.

"This gives us new tools to understand in a more concrete manner how biomechanical factors in the central nervous system influence the health of cells when we are healthy and when we suffer from diseases. This will not only have major importance for our understanding of how diseases come about in the central nervous system, but also for future disease treatment", said the researchers.

The central nervous system, which includes the brain, spinal cord and retinas, is a complicated organ, especially in terms of structure. The entire system is under the mechanical influence of fluid pressure, among other factors. The new data from the group in Lund indicates that when the biomechanical balance is disturbed, as happens in retinal detachment and glaucoma, the normal function of the retina is lost, resulting in serious sight impairment or blindness.


Contact: Fredrik Ghosh
Lund University

Related medicine news :

1. UZH research team discovers the origins of key immune cells
2. For brain tumors, origins matter
3. Tracking the origins of HIV
4. UW researchers discover the brain origins of variation in pathological anxiety
5. AstraZeneca and DNDi to collaborate on drug screening for neglected tropical diseases
6. Range of diagnostic spinal fluid tests needed to differentiate concurrent brain diseases
7. Centre for Global Non-Communicable Diseases launched to tackle killer diseases
8. A*STAR scientists discover switch to boost anti-viral response to fight infectious diseases
9. Comprehensive report documents impact of urologic diseases on American public
10. Super-sensitive tests could detect diseases earlier
11. Outstanding high school students receive awards to stimulate research interest in digestive diseases
Post Your Comments:
(Date:6/24/2016)... ... June 24, 2016 , ... June 19, 2016 is ... associated with chronic pain and the benefits of holistic treatments, Serenity Recovery Center ... suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a disorder of ...
(Date:6/24/2016)... ... 2016 , ... Global law firm Greenberg Traurig, P.A. announced that 20 Florida ... their peers for this recognition are considered among the top 2 percent of lawyers ... as members of this year’s Legal Elite Hall of Fame: Miami Shareholders Mark ...
(Date:6/24/2016)... ... ... of Topricin and MyPainAway Pain Relief Products, join The ‘Business for a Fair Minimum Wage’ ... 2020 and then adjusting it yearly to increase at the same rate as the median ... floor does not erode again, and make future increases more predictable. , The company is ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Haute ... Dr. Barry M. Weintraub as a prominent plastic surgeon and the network’s newest ... world, and the most handsome men, look naturally attractive. Plastic surgery should be ...
(Date:6/24/2016)... ... ... National recruitment firm Slone Partners is pleased to announce the ... as Vice President of North American Capital Sales at HTG Molecular . ... team in the commercialization of the HTG EdgeSeq system and associated reagents in North ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... Calif. , June 23, 2016 ... CST on Thursday, July 7, 2016 , , , , ... ) , , , , EXPERT PANELISTS:  , , ... Naik; Senior Industry Analyst, Christi Bird; Senior Industry Analyst, Divyaa Ravishankar ... The global pharmaceutical industry is witnessing an exceptional ...
(Date:6/23/2016)... 23, 2016  Astellas today announced the establishment of Astellas Farma Colombia (AFC), a new affiliate with operations headquartered ... Latin America . ... ... ... ...
(Date:6/23/2016)... 2016  Guerbet announced today that it has been ... Award . One of 12 suppliers to ... its support of Premier members through exceptional local customer ... commitment to lower costs. ... our outstanding customer service from Premier," says Massimo ...
Breaking Medicine Technology: