Navigation Links
New view of origins of eye diseases
Date:4/3/2013

Using new technology and new approaches, researchers at Lund University in Sweden hope to be able to explain why people suffer vision loss in eye diseases such as retinal detachment and glaucoma.

Research on diseases of the eye such as retinal detachment and glaucoma has until now focused on the biochemical process that takes place in the eye in connection with the diseases.

Fredrik Ghosh and Linna Taylor have concentrated instead on attempting to understand what happens on a biomechanical level in the diseases and have produced results that have drawn a lot of interest from experts.

"We have not previously understood the mechanisms behind glaucoma and retinal detachment, but we knew that these diseases had a strong mechanical component. Our findings could form an initial explanation as to why we develop these diseases", said eye researchers Fredrik Ghosh and Linna Taylor.

Using new technology, the eye researchers at the Department of Clinical Sciences in Lund, in collaboration with researchers at the Department of Biology at Lund University, have developed a method to investigate the importance of the biomechanical environment within the central nervous system.

For their studies, they grow retinal tissue from adult pigs in a stretched state similar to the normal mechanical state present in the living eye. Compared with unstretched tissue, which in cultures dies after a few days when the retina's mechanical balance is disturbed, studies can now be performed for up to ten days in retina with a well-preserved structure and significantly higher cell survival.

"This gives us new tools to understand in a more concrete manner how biomechanical factors in the central nervous system influence the health of cells when we are healthy and when we suffer from diseases. This will not only have major importance for our understanding of how diseases come about in the central nervous system, but also for future disease treatment", said the researchers.

The central nervous system, which includes the brain, spinal cord and retinas, is a complicated organ, especially in terms of structure. The entire system is under the mechanical influence of fluid pressure, among other factors. The new data from the group in Lund indicates that when the biomechanical balance is disturbed, as happens in retinal detachment and glaucoma, the normal function of the retina is lost, resulting in serious sight impairment or blindness.


'/>"/>

Contact: Fredrik Ghosh
46-768-643-033
Lund University
Source:Eurekalert

Related medicine news :

1. UZH research team discovers the origins of key immune cells
2. For brain tumors, origins matter
3. Tracking the origins of HIV
4. UW researchers discover the brain origins of variation in pathological anxiety
5. AstraZeneca and DNDi to collaborate on drug screening for neglected tropical diseases
6. Range of diagnostic spinal fluid tests needed to differentiate concurrent brain diseases
7. Centre for Global Non-Communicable Diseases launched to tackle killer diseases
8. A*STAR scientists discover switch to boost anti-viral response to fight infectious diseases
9. Comprehensive report documents impact of urologic diseases on American public
10. Super-sensitive tests could detect diseases earlier
11. Outstanding high school students receive awards to stimulate research interest in digestive diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2017)... ... May 24, 2017 , ... Last month, representatives from ... employees, and town officials to celebrate the grand opening of the 87,000 square ... as part of its ongoing relationship with RWJBarnabas Health, New Jersey’s largest health ...
(Date:5/24/2017)... ... May 24, 2017 , ... NucleusHealth ... interpretation, has received U.S. Food and Drug Administration (FDA) 510(k) clearance ... and secure cloud platform for medical image management. At the core is patented ...
(Date:5/24/2017)... ... May 24, 2017 , ... STATEMENT OPPOSING PRESIDENT DONALD TRUMP’S ... Donald Trump’s budget, “A New Foundation for American Greatness—President's Budget FY 2018,” because ... marginalizes underserved populations, undermines productivity, and destroys the social safety net needed by ...
(Date:5/24/2017)... ... May 24, 2017 , ... Medic CE , a Career Step company, ... Septic Shock” hosted by the Journal of Emergency Medical Services (JEMS). The free webinar, ... be presented by Captain Rommie Duckworth, LP, a career fire captain as well as ...
(Date:5/24/2017)... ... May 24, 2017 , ... Rob Lowe is a sought after ... Public Television. “Informed” brings the public important topics from all aspects of life, and ... feet and issues surrounding feet and ankles. , Podiatry is essential to people’s overall ...
Breaking Medicine News(10 mins):
(Date:5/4/2017)... May 4, 2017   BioLife Solutions , Inc. ... and marketer of proprietary clinical grade hypothermic storage ... the "Company"), today announced that the Company,s first quarter ... on Thursday, May 11, 2017, and that the Company ... 1:30 p.m. PT that afternoon. Management will provide an ...
(Date:5/3/2017)... ROCKVILLE, Md. , May 3, 2017 /PRNewswire/ ... revenue growth of nine percent next year and ... solid organ and hematopoietic stem cell (HSCT) or ... and donor. Molecular testing technologies are well-suited for this ... healthcare-only market research publisher Kalorama Information. The various ...
(Date:5/3/2017)... 2017  West Pharmaceutical Services, Inc. (NYSE: WST), ... drug administration, announced today that Fran DeGrazio ... and Diane Paskiet , Director, Scientific Affairs, ... on West,s expertise in the areas of safety ... providing commentary on updated industry guidance. ...
Breaking Medicine Technology: