Navigation Links
New vaccine candidate shows strong potential to prevent highly contagious norovirus
Date:3/15/2011

COLUMBUS, Ohio Scientists have shown that an experimental vaccine against the human norovirus the bug behind about 90 percent of highly contagious nonbacterial illnesses that cause diarrhea and vomiting can generate a strong immune response in mice without appearing to cause the animals any harm.

Using a novel viral vector-based method to grow and deliver the vaccine that has shown promise in other agents designed to fight such infections as HIV and hepatitis C, the researchers are the first to test this vaccine design method's effectiveness against the human norovirus.

Animals receiving the vaccine developed high levels of antibodies, a robust white blood cell response and an additional immune response in the area of the body most affected by this particular infection the gastrointestinal system.

The researchers say this study supports the use of viral vector-based techniques as a new way to develop vaccines for human norovirus and other viruses that cannot grow in cell cultures. It also suggests that these Ohio State University scientists could be well on their way to developing a safe vaccine against a highly problematic pathogen that causes millions of gastrointestinal illnesses every year in the United States.

"The mice in our study developed a much higher antibody response to our vaccine candidate than they did to a more traditional vaccine. That's one of the keys, to have a sustained antibody response, so that when the disease comes along, you can neutralize the virus and protect yourself," said Jianrong Li, assistant professor of food science and technology at Ohio State and senior author of the study.

Li co-authored the study with Yuanmei Ma, a graduate student in food science and technology. The research appears in the current issue of the Journal of Virology.

The Centers for Disease Control and Prevention estimates that more than 21 million cases of acute gastroenteritis characte
'/>"/>

Contact: Jianrong Li
li.926@osu.edu
614-688-5728
Ohio State University
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Research may lead to new and improved vaccines
2. Sones Innovation Award honors breast cancer vaccine research
3. Using a molecular switch to turn on cancer vaccines
4. An Alzheimers vaccine in a nasal spray
5. Experts explore vaccines: Science, legal, social issues at New York Academy of Sciences
6. New vaccine technology protects mice from hepatitis C virus
7. Supreme Court Rejects Vaccine-Safety Lawsuit
8. MIT engineers design new nanoparticle that could lead to vaccines for HIV, malaria, other diseases
9. Efficacy of tuberculosis vaccine enhanced
10. Universal flu vaccine study yields success in mice
11. International Vaccine Institute announces launch of Dengue Vaccine Initiative
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2015)... Angeles, CA (PRWEB) , ... August 27, 2015 , ... ... Association and the American Heart Association have released new guidelines to educate doctors and ... the last update to these particular guidelines came in 2007, so the new version ...
(Date:8/27/2015)... (PRWEB) , ... August 27, 2015 , ... Thriveology Founders, ... the featured speakers at The Amazing Aging Expo in Denver, Colorado on Saturday, August ... doctors are consistently featured in media outlets as health authorities, and will present a ...
(Date:8/27/2015)... ... August 27, 2015 , ... ... the exploding legal marijuana industry with the launch of its Doobster platform, a ... marijuana to order products from their smart phones and tablets. Well, Doobster, ...
(Date:8/27/2015)... ... August 27, 2015 , ... About 10 percent of mothers ... Gulf Coast, killing more than 1,800 people, displacing hundreds of thousands and causing ... University study. , While most people don’t develop persistent depression after a major ...
(Date:8/27/2015)... ... August 27, 2015 , ... The Naderi Center is proud to ... a cutting-edge, noninvasive procedure to improve submental fat. The first and only Food ... without surgery. Dr. Kulak is the only Board Certified surgeon in the D.C., ...
Breaking Medicine News(10 mins):Health News:Article on New Diabetic Care Guidelines Shines Brightly on Weight Loss Surgery, notes Beverly Hills Physicians 2Health News:Article on New Diabetic Care Guidelines Shines Brightly on Weight Loss Surgery, notes Beverly Hills Physicians 3Health News:Internationally-renowned Naturopathic Doctor and Chiropractor Team up to Reveal Secrets of Avoiding Disease 2Health News:Doobster Launches a Nationwide, Comprehensive On-Demand Medical Marijuana App 2Health News:Doobster Launches a Nationwide, Comprehensive On-Demand Medical Marijuana App 3Health News:Doobster Launches a Nationwide, Comprehensive On-Demand Medical Marijuana App 4Health News:Doobster Launches a Nationwide, Comprehensive On-Demand Medical Marijuana App 5Health News:About 10 Percent of Mothers Experienced Depression Two Years After Hurricane Katrina, New Study Shows 2Health News:Noninvasive Double Chin Elimination Now Available in Herndon and Chevy Chase 2Health News:Noninvasive Double Chin Elimination Now Available in Herndon and Chevy Chase 3
... ... in Ophthalmology (JCAHPO), and the Association of Technical Personnel in Ophthalmology (ATPO) proudly launched ... Reference Guide for the Ophthalmic Technician. , ... St. Paul, MN (Vocus) November 10, 2009 -- Compact, ...
... HATBORO, Pa., Nov. 10 InfoLogix, Inc. (Nasdaq: ... solutions for the healthcare and commercial industries, today announced ... exception to NASDAQ,s stockholder approval requirements, in accordance with ... on this exception to complete a proposed plan of ...
... ... Arm in the Last 30 Years" , ... Gulf Breeze, Fla. (Vocus) November 10, 2009 -- The Andrews-Paulos Research & ... Rounds presentation on November, 19, 2009 at 5:30 p.m. (CT). Renowned orthopaedic and sports ...
... Better coordination urged to stem re-admission rate of nearly 1 ... Almost a quarter of the people on Medicare who are ... a month of discharge, a new study reveals. , That ... assistant professor of geriatrics and palliative medicine at the Mount ...
... YORK Medications frequently given to cancer patients to ... increased risk of deep vein thrombosis or pulmonary embolism, ... M.S., co-director of the breast cancer program at the ... Medical Center. The findings will be published online on ...
... Amalgamated Capital, a newly formed division of Amalgamated ... in the recapitalization of Oklahoma City-based 180 Medical, Inc., ... Amalgamated Capital provides senior cash flow debt financing to ... firms and other investors are financial sponsors. , 180 ...
Cached Medicine News:Health News:JCAHPO/ATPO Pocket Guide Launches for Eye Care Professionals 2Health News:JCAHPO/ATPO Pocket Guide Launches for Eye Care Professionals 3Health News:InfoLogix Announces Receipt of NASDAQ Waiver for Stockholder Approval of Restructuring and Extension to Stockholder's Equity Requirement 2Health News:InfoLogix Announces Receipt of NASDAQ Waiver for Stockholder Approval of Restructuring and Extension to Stockholder's Equity Requirement 3Health News:InfoLogix Announces Receipt of NASDAQ Waiver for Stockholder Approval of Restructuring and Extension to Stockholder's Equity Requirement 4Health News:InfoLogix Announces Receipt of NASDAQ Waiver for Stockholder Approval of Restructuring and Extension to Stockholder's Equity Requirement 5Health News:Orthopaedic Surgeon and AOSSM President Dr. James Andrews to Discuss Injury Prevention 2Health News:Orthopaedic Surgeon and AOSSM President Dr. James Andrews to Discuss Injury Prevention 3Health News:The Revolving Door of Heart Failure Hospitalization 2Health News:The Revolving Door of Heart Failure Hospitalization 3Health News:Drugs to treat anemia in cancer patients linked to thromboembolism 2Health News:Drugs to treat anemia in cancer patients linked to thromboembolism 3Health News:Amalgamated Capital Serves as Syndication Agent in the Recapitalization of 180 Medical, Inc. 2Health News:Amalgamated Capital Serves as Syndication Agent in the Recapitalization of 180 Medical, Inc. 3Health News:Amalgamated Capital Serves as Syndication Agent in the Recapitalization of 180 Medical, Inc. 4
(Date:8/27/2015)... , August 27, 2015 ... convened in Boston on July ... in an effort to more fully exploit the potential ... applied to brain diseases. "As an established ... a responsibility to assume a leadership role - in ...
(Date:8/27/2015)... , Aug. 27, 2015  CytomX Therapeutics, Inc., ... treatment of cancer, today announced that Rachel ... company,s Board of Directors, has been appointed chief ... Eli Lilly and AstraZeneca, and also oversaw clinical ... checkpoint inhibitor, at Bristol-Myers Squibb and the development ...
(Date:8/27/2015)... Mass. , Aug. 27, 2015 Oryzon today ... Renshaw 17th Annual Global Investment Conference in New ... ORYZON will be represented by President and CEO Carlos ... Dr. Buesa will present this information on Thursday September 10, ... Floor).  The company is completing preclinical development of its ORY-2001 ...
Breaking Medicine Technology:New Elekta Consortium to Push Frontiers of Linear Accelerator-Based Stereotactic Radiation Therapy for the Brain 2New Elekta Consortium to Push Frontiers of Linear Accelerator-Based Stereotactic Radiation Therapy for the Brain 3Immuno-Oncology Veteran Rachel Humphrey, M.D., Joins CytomX as Chief Medical Officer 2Immuno-Oncology Veteran Rachel Humphrey, M.D., Joins CytomX as Chief Medical Officer 3ORYZON to Present at Rodman & Renshaw 17th Annual Global Investment Conference 2ORYZON to Present at Rodman & Renshaw 17th Annual Global Investment Conference 3ORYZON to Present at Rodman & Renshaw 17th Annual Global Investment Conference 4
... to Educate Women About this Common Condition, MILWAUKEE, ... at the Hyatt Regency Milwaukee hotel (333 West Kilbourn ... 7:30 pm to talk about her,experience with stress urinary ... Down There?: Breaking the Ice About SUI, a,national public ...
... Opiate-Like Side Effects For Several ... Months Following a Single Administration, SOUTH SAN FRANCISCO, Calif., ... that it has initiated a new,Phase 2 study of Adlea(TM) ... total knee replacement surgery, also called,total knee arthroplasty (TKA). Adlea ...
Cached Medicine Technology:Bonnie Blair to Break the Ice About Stress Urinary Incontinence in Milwaukee 2Bonnie Blair to Break the Ice About Stress Urinary Incontinence in Milwaukee 3Anesiva Initiates New Phase 2 Trial of Adlea(TM) for Pain Relief Following Knee Replacement Surgery 2Anesiva Initiates New Phase 2 Trial of Adlea(TM) for Pain Relief Following Knee Replacement Surgery 3Anesiva Initiates New Phase 2 Trial of Adlea(TM) for Pain Relief Following Knee Replacement Surgery 4
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: