Navigation Links
New understanding of basic units of memory
Date:9/19/2007

DURHAM, N.C. A molecular recycling plant permits nerve cells in the brain to carry out two seemingly contradictory functions changeable enough to record new experiences, yet permanent enough to maintain these memories over time.

The discovery of this molecular recycling plant, detailed in a study appearing early online Sept. 19 in the journal Neuron, provides new insights into how the basic units of learning and memory function. Individual memories are burned onto hundreds of receptors that are constantly in motion around nerve synapses gaps between individual nerve cells crucial for signals to travel throughout the brain.

According to the studys leader, Duke University Medical Center neurobiologist Michael Ehlers, M.D., Ph.D., these receptors are constantly moving around the synapse and often times they disappear or escape. Ehlers discovered that a specific set of molecules catch these elusive receptors, take them to the recycling plant where they are reprocessed and returned to the synapse intact.

These receptors constantly escape the synapse and are in a perpetual state of recycling, said Ehlers, who is also a Howard Hughes Medical Institute investigator. This process occurs on a time scale of minutes or hours, so the acquisition of new neurotransmitter receptors and their recycling is an on-going process. Memory loss may result from receptors escaping from the synapse.

All this activity takes place on millions of tiny nubs, or protrusions in the synapses known as dendritic spines. The recycling plants are located within the body of these dendritic spines.

We believe that the existence of this recycling ability explains in part how individual dendritic spines retain their unique identity amidst this constant molecular turnover, Ehlers said. The system is simultaneously dynamic and stable.

While these findings should be able to help neurobiologists as they attempt to understand the molecular foundations
'/>"/>

Contact: Richard Merritt
Merri006@mc.duke.edu
919-660-1309
Duke University Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Understanding The Predictors Of Prostate Cancer
2. Understanding Restless Legs Syndrome
3. Understanding Lung Cancer Metastasis
4. Understanding The Link Between Hormone Replacement and Respiratory Disease
5. Understanding The Risks Of Hormone Therapy
6. Understanding The Link Between Metabolic Syndrome And Drinking Patterns
7. A Better Understanding Of The Brain Network
8. Understanding The Predictor’s Of Alzheimer’s Diseae
9. Understanding The Harmful Effects Of Radiation Exposure
10. Understanding The Origin Of Tumors
11. Understanding Insulin Resistance
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/18/2014)... The famous review site Top10BestSEOHosting.com has recently compared many ... suppliers carefully, today it announces that HostMonster, GreenGeeks and ... first half of 2014. , HostMonster is an ... package helps business companies and individuals get high-powered service ... rated hosting provider, it insists on offering outstanding customer ...
(Date:10/18/2014)... (PRWEB) October 19, 2014 ... announced that Hostgator ( http://secure.hostgator.com/~affiliat/cgi-bin/affiliates/clickthru.cgi?id=seohosts ), JustHost ... suppliers in 2014. , “There are ... world, but good suppliers are not too ... and FatCow are the most outstanding suppliers ...
(Date:10/18/2014)... Operators in the Carpet ... carpet cleaning services, such as steam cleaning, dry-cleaning ... every one to two years. According to IBISWorld ... plummeted during the peak of the global financial ... carpet cleaning.” The upward trend in household discretionary ...
(Date:10/18/2014)... TX (PRWEB) October 18, 2014 ... Chinese Chondroitin sulfate Industry, 2009-2019 is a ... Global and Chinese Chondroitin sulfate industry. The ... Chondroitin sulfate including its classification, application and ... and China’s top manufacturers of Chondroitin sulfate ...
(Date:10/18/2014)... determined dieters can fail if they don,t have a ... Their new study included 240 obese people. All of ... factors that increase the risk of heart disease, stroke ... to make lifestyle changes, including improved eating, the study ... clinical trial comparing two dietary interventions: the American ...
Breaking Medicine News(10 mins):Health News:Top10BestSEOHosting.com: HostMonster, GreenGeeks And FatCow Are The Best PHP Hosting Suppliers In The First Half Of 2014 2Health News:Top10BestSEOHosting.com: Best Reseller Hosting Companies Announced 2Health News:Carpet Cleaning Services in Australia Industry Market Research Report Now Available from IBISWorld 2Health News:Carpet Cleaning Services in Australia Industry Market Research Report Now Available from IBISWorld 3Health News:Chondroitin Sulfate Industry Global & Chinese Forecast to 2019 Now Available at RnRMarketResearch.com 2Health News:Chondroitin Sulfate Industry Global & Chinese Forecast to 2019 Now Available at RnRMarketResearch.com 3Health News:Chondroitin Sulfate Industry Global & Chinese Forecast to 2019 Now Available at RnRMarketResearch.com 4Health News:Dieters May Be Thwarted by Absence of Healthy Foods 2
... America, Inc. (SAI),today announced the 1,000th activation ... Hagerstown Medical Laboratory, Maryland.,SNCS is a remote ... tracks instrument performance data from Sysmex analyzers ... SNCS enables proactive response to potential,instrument problems, ...
... Medications May Disappear or be Hindered For ... California,s Most Vulnerable Citizens, SACRAMENTO, Calif., ... against the California Department of,Health Care Services and its director ... pharmacies from going into effect on July 1,2008. The action ...
... Raising Awareness ... & Education, NEW YORK, June 10 MGM ... branding initiative, PiNKiTUDE, which,will encompass a wide range of ... earmarked for the global breast cancer organization,Susan G. Komen ...
... June 5, 2008 Over 1.3 million Americans ... of the joints. RA is a disabling condition, and ... pain and loss of function in affected areas. A ... Journal of Periodontology , the official publication of ...
... regimen of the immune-suppressing drug cyclophosphamide seems to slow ... small group of patients studied and may even restore ... report. The findings in nine people, most of whom ... treat a disease that tends to progress relentlessly. , ...
... Promote Health and ... Wellness, ... meeting consumers, health and wellness needs, the Kellogg,Company joined the Department of ... companies,promoting eating and physical fitness for families that is consistent with,MyPyramid. The ...
Cached Medicine News:Health News:Sysmex America to Enable Prolonged Hematology Instrument Uptime for Hagerstown Medical Laboratory With 1,000th SNCS Activation 2Health News:Sysmex America to Enable Prolonged Hematology Instrument Uptime for Hagerstown Medical Laboratory With 1,000th SNCS Activation 3Health News:Eight California Pharmacies File Lawsuit Against the California Department of Health Care Services to Stop the 10 Percent Medi-Cal Provider Cuts to Pharmacies 2Health News:PiNKiTUDE, New Cause Marketing Initiative Inspired by MGM's Pink Panther, Benefits Susan G. Komen for the Cure(R) 2Health News:PiNKiTUDE, New Cause Marketing Initiative Inspired by MGM's Pink Panther, Benefits Susan G. Komen for the Cure(R) 3Health News:PiNKiTUDE, New Cause Marketing Initiative Inspired by MGM's Pink Panther, Benefits Susan G. Komen for the Cure(R) 4Health News:Researchers uncover higher prevalence of periodontal disease in rheumatoid arthritis patients 2Health News:'HiCy' drug regimen reverses ms symptoms in selected patients 2Health News:'HiCy' drug regimen reverses ms symptoms in selected patients 3Health News:Kellogg and MyPyramid - Helping Families Live Well Today and Every Day 2Health News:Kellogg and MyPyramid - Helping Families Live Well Today and Every Day 3Health News:Kellogg and MyPyramid - Helping Families Live Well Today and Every Day 4
(Date:10/16/2014)... , Oct. 16, 2014 The ... guidance on the application of single-use, or ... pharmaceutical and biopharmaceutical products with the publication ... Application of Single-Use Systems in Pharmaceutical ... described as single-use systems (SUS) or single-use ...
(Date:10/16/2014)... , Oct. 16, 2014 Curtis & ... under 3 weeks away from hosting their co-located ... Oral Drug Formulation Innovations Summit taking place ... San Diego, CA. November,s events ... organizations in streamlining the bioequivalence testing process, as well ...
(Date:10/16/2014)... PHILADELPHIA , Oct. 16, 2014 Ninety ... (ALL) who had relapsed multiple times or failed to ... an investigational personalized cellular therapy, CTL019, developed at the ... The results published today in The ... new data, which builds on preliminary findings presented at ...
Breaking Medicine Technology:PDA Offers Help in Applying Single-Use Systems to Bio/Pharma Operations 2Simplifying the Bioequivalence Testing Process and Optimizing Oral Formulation Development via Unifying the Global Life Science Community this November in San Diego 2Personalized Cellular Therapy Achieves Complete Remission in 90 Percent of Acute Lymphoblastic Leukemia Patients Studied 2Personalized Cellular Therapy Achieves Complete Remission in 90 Percent of Acute Lymphoblastic Leukemia Patients Studied 3Personalized Cellular Therapy Achieves Complete Remission in 90 Percent of Acute Lymphoblastic Leukemia Patients Studied 4Personalized Cellular Therapy Achieves Complete Remission in 90 Percent of Acute Lymphoblastic Leukemia Patients Studied 5Personalized Cellular Therapy Achieves Complete Remission in 90 Percent of Acute Lymphoblastic Leukemia Patients Studied 6
... Health Corp. (Nasdaq: WBMD ) today announced the ... amount of 2.50% Convertible Notes due 2018 (including $50 million ... full of the initial purchaser,s over-allotment option).  The notes were ... under the Securities Act of 1933.   The ...
... NEW YORK, Jan. 11, 2011 Reportlinker.com ... is available in its catalogue: ... Price cuts set to negatively impact both ... http://www.reportlinker.com/p0360216/Spain-Pharmaceutical-Market-Overview – Price-cuts-set-to-negatively-impact-both-branded-and-generics-companies.html ...
Cached Medicine Technology:WebMD Closes Offering of 2.50% Convertible Notes Due 2018 2Reportlinker Adds Spain Pharmaceutical Market Overview - Price cuts set to negatively impact both branded and generics companies 2
... physicians looking for a traditional ... communications with electronic storage features, ... best of both worlds. It ... features of the Atria 3000 ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: