Navigation Links
New treatment method safe, effective for advanced melanoma patients
Date:6/5/2010

CHICAGO, June 5 Patients undergoing treatment for melanoma that has spread to the liver may respond well to chemotherapy delivered directly into the liver's blood vessels, according to a study sponsored by the National Cancer Institute and Delcath Systems Inc., and led by James F. Pingpank, M.D., associate professor of surgery, University of Pittsburgh School of Medicine, and surgical oncologist with UPMC Cancer Centers. The results will be disclosed in an oral presentation on June 5 in Chicago at the 46th annual meeting of the American Society of Clinical Oncology (ASCO).

"Once melanoma spreads to the liver, a patient's life expectancy typically ranges from six to nine months," said Dr. Pingpank. "We hoped this study would not only show an increase in progression-free survival rates for these patients, but also lead to a standard of care for the disease."

The phase III trial enrolled 93 patients from 10 different sites across the country between February 2006 and October 2009. Its primary goal was to double the length of hepatic progression-free survival for patients with melanoma that had spread to the liver. Patients received either percutaneous hepatic perfusion (PHP) with the drug melphalan, meaning the chemotherapy was delivered directly into the blood vessels of the liver, or the treatment considered the best alternative regimen by their treating physician. If a patient not receiving PHP had disease progression, he or she could cross over to the PHP arm of the trial.

"Not only did we achieve our goal, we surpassed it," said Dr. Pingpank. "This is particularly exciting because so far oncologists haven't been able to recommend a standard of care for patients with melanoma that has spread to the liver. PHP appears to control tumors in the liver and extend life expectancy for these patients, whether their melanoma began as skin cancer or as ocular melanoma, a less common form of the disease that starts in the eye. Fifty percent of
'/>"/>

Contact: Courtney McCrimmon
McCrimmonCP@upmc.edu
412-715‑8894
University of Pittsburgh Schools of the Health Sciences
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Combination treatment regimen not effective against advanced melanoma
2. Researchers Report Treatment Headway Against Lung Cancer
3. Nasendoscopy proves useful in predicting treatment success in sleep apnea patients
4. Mount Sinai researchers approaching universal treatment for all strains of influenza
5. New Website Created Just For Car Accident Victims… Reveals Chiropractic Treatment Is Extremely Effective For Whiplash, Neck and Back Pain
6. The Harley Medical group launches exclusive treatment for stretch marks and scars
7. Local Walgreen's Drug Stores Now Stock ZymaDerm™ The Painless Treatment for Molluscum Contagiosum
8. UT Southwestern investigators perform head-to-head comparison of incontinence treatments
9. New cancer guidelines: Exercise during and after treatment is now encouraged
10. Acne Treatment Reviewed by Leading Dermatologists in Honor of Acne Awareness Month
11. Hair Loss Research Study Reveals Important Breakthrough in the Treatment of Male Pattern Baldness
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... After a 13-year absence from active ... to the stage to entertain his many worldwide fans. ... and the successful tour has been steadily expanding since ... Visit Ticketability.com for a large inventory of ... fair prices. , Music fans have had a long ...
(Date:12/19/2014)... News) -- A new study suggests a possible link ... flashes and night sweats -- and higher rates of ... common during menopause, affecting about 60 percent of women. ... menopause, since they then face a higher risk of ... who exhibit moderate or severe menopausal symptoms are more ...
(Date:12/19/2014)... (HealthDay News) -- Prostaglandin analogue eye drops -- a ... risk of vision loss in patients with the eye ... by David Garway-Heath, of the Moorfields Eye Hospital and ... more than 500 people newly diagnosed with open-angle glaucoma ... one of the leading causes of blindness. About ...
(Date:12/17/2014)... Providence, RI (PRWEB) December 17, 2014 ... nationally recognize private practices that have made outstanding ... and in support and progression of private practice ... the American Physical Therapy Association. , On behalf ... DPT, OCS, owner and CEO of Performance accepted ...
(Date:12/17/2014)... Crest Hill, IL (PRWEB) December 17, 2014 ... of 2015 Awards celebrate the best of the best ... States. The award is only given to communities and ... families through the SeniorAdvisor.com site. Of the nearly 100,000 ... with this award. Winners of the SeniorAdvisor.com Best of ...
Breaking Medicine News(10 mins):Health News:Garth Brooks Tickets for Joe Louis Arena: Ticketability.com Becomes a Popular Destination for Discount Tickets for Garth Brooks’ Detroit Concerts Set for February 27-28 2Health News:Severe Hot Flashes During Menopause May Raise Hip Fracture Risk Later: Study 2Health News:Study Supports Benefit of Widely Used Glaucoma Drug 2Health News:Performance Physical Therapy Awarded with Jayne L. Snyder Private Practice of the Year 2014 2Health News:The Inn at Willow Falls - Crest Hill, IL Wins 2015 Best of Assisted Living Award from SeniorAdvisor.com 2Health News:The Inn at Willow Falls - Crest Hill, IL Wins 2015 Best of Assisted Living Award from SeniorAdvisor.com 3
... risk of developing leukemia as a side effect of a ... according to a study presented as part of the Late-breaking ... Meeting in Seattle, April 25 - May 2, 2009.Mitoxantrone is ... several forms of advancing MS. It is one of only ...
... manage stress at work and in their homes is ... million National Institutes of Health grant that will also ... reduce employee stress and promote well-being., "We,re seeing that ... that can increase stress and reduce quality of life ...
... related art ROSEMONT, Ill., April 30 Wartime experiences not ... the physicians and medical teams who treat them. As ... orthopaedic surgeons who are caring and have cared for them, ... (AAOS) is opening the call for entries to a unique, ...
... Patients in Many Markets, Dayton , ... Area Quick-Clinic Void with Kroger Partnership, ... HealthLeaders-InterStudy, a leading provider of managed care market intelligence, ... across the country, they have not taken off in the ...
... the immune system attacks the body,s own material just as ... MS for short, is just one such autoimmune disease, and ... 20 to 30 years age group. The disease can have ... attack the central nervous system. It has long been assumed ...
... Inc. today announced that Chris Streng, Vice President, Finance ... been elected to the Codexis Board of Directors, bringing ... Houston, Texas, where he is employed by Shell Downstream ... petrochemical plants in the Shell Group worldwide. He ...
Cached Medicine News:Health News:Risk of Leukemia with Multiple Sclerosis Drug Higher Than Thought 2Health News:Penn State plays integral role in $35 million stress project 2Health News:War and Musculoskeletal Injury Prompt Artistic Expression 2Health News:War and Musculoskeletal Injury Prompt Artistic Expression 3Health News:Physician-Led Quick-Care Clinics Protect Patient Base 2Health News:Physician-Led Quick-Care Clinics Protect Patient Base 3Health News:Gray matter under attack in multiple sclerosis 2Health News:Gray matter under attack in multiple sclerosis 3Health News:Shell Finance Executive Streng Elected to Codexis Board 2
(Date:12/17/2014)... , Dec. 17, 2014  ImmunoCellular Therapeutics, Ltd. ... Patent and Trademark Office (USPTO) has issued a ... dendritic cell-based immunotherapeutic vaccine targeting six tumor antigens ... of US Patent No. 8,871,211, which issued October ... by administering a dendritic cell composition comprising peptide ...
(Date:12/17/2014)... 2014 PCCA received the Autism Hope ... ) program seal for best practices in meeting ... medical practices, materials and goods that meet strict ... Children affected by autism often have unique physical ... ingredients found in food and medicine – for ...
(Date:12/15/2014)... 2014 Research and Markets ( http://www.researchandmarkets.com/research/32cmct/inferior_vena ... Vena Cava (IVC) Filters - Global Trends, Estimates and ... http://photos.prnewswire.com/prnh/20130307/600769 Global Inferior ... US$435 million by 2016. The North America ... global value while Europe claims ...
Breaking Medicine Technology:ImmunoCellular Therapeutics Announces Issuance of Key Patent For ICT-107 Cancer Vaccine 2Parents Of Children With Autism Spectrum Disorder Have New Options When Administering Medications 2Parents Of Children With Autism Spectrum Disorder Have New Options When Administering Medications 3Inferior Vena Cava (IVC) Filters - Global Trends, Estimates and Forecasts, 2012-2018 2Inferior Vena Cava (IVC) Filters - Global Trends, Estimates and Forecasts, 2012-2018 3Inferior Vena Cava (IVC) Filters - Global Trends, Estimates and Forecasts, 2012-2018 4
Amylase (EPS-G7, kinetics), Wavelength: 405 nm. Linear range; 5-1500 IU/L....
g-GT Liquid Reagent (Kinetic Method). Wavelength: 405 nm. Linear range: 0-200 U/mL. Prepare Working Reagent in the ratio of 5 parts R1 to 1 part of R2, (i.e., 50 mL R1 and 10 mL R2)....
Intended for the quantitative determination of calcium in serum. Endpoint Reaction. Reaction complete within one minute, color developed is stable for 30 minutes. Wavelength: 570 nm. Linearity: 16 mg...
... the quantitative determination of alanine ... plasma. Two vials, dry powder ... be purchased separately for conformity ... Wavelength: 340 nm. Linearity: 268 ...
Medicine Products: