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New treatment approach to rare cancer results in prolonged survival
Date:5/26/2010

9181.html">Julian Molina, M.D., Ph.D.

However, the benefits come at the cost of toxicity, the researchers add.

"Toxicity is a very real issue, to the point that many patients required hospitalization related to side effects from the therapy, but no deaths resulted from therapy," says Dr. Bible, who is presenting the results. Of the four patients who have died to date, all succumbed to their disease, not to treatment effects.

Dr. Bible added that a clinical trial formally testing two approaches to the addition of chemotherapy to radiotherapy in a randomized fashion will be launched in the fall and will include other centers nationwide. The new study will use a related chemotherapy drug, paclitaxel, as well as the addition of a targeted therapy. Dr. Bible will co-lead the study along with Eric Sherman, M.D., from Memorial Sloan-Kettering Cancer Center and others.

Mayo Clinic is regarded as a center of excellence for the treatment of anaplastic thyroid cancer due to the clinic's specialization in thyroid and endocrine cancers -- an expertise that dates back to the practice of thyroid surgeon Charles H. Mayo, M.D., one of the founders of Mayo Clinic. "We have become seriously focused on how to treat these and other rare endocrine cancers more effectively," Dr. Bible says.


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Contact: Karl Oestreich
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Page: 1 2

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