Navigation Links
New topical approach to treating nail fungus circumvents problems with current therapy
Date:10/28/2008

WASHINGTON, D.C. (October 27, 2008) A novel topical therapy for nail fungus, NB-002, has demonstrated a new topical approach to healing nail fungus by penetrating skin pores and diffusing through the skin that surrounds the entire nail plate, according to a study conducted by NanoBio Corporation.

The data represent a unique approach to treating nail fungus (onychomycosis), which resists topical therapies because they cannot penetrate the nail and access the site of infection. The results were reported this morning at the 48th annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)/Infectious Diseases Society of America (IDSA) 46th annual meeting in Washington, D.C.

"In testing NB-002 on human cadaver skin, we have demonstrated that the lotion permeates and then laterally diffuses across tissue plains in the epidermis and the dermis to more than 1 centimeter away from the site of application," said Susan Ciotti, Ph.D., director of formulations and research and development, and presenting author of the data.

"The average great toenail measures 22 millimeters across, so we are able to deliver NB-002 across the entire span of an infected human large toenail, a huge advance in the treatment of onychomycosis," Ciotti said.

Because of its novel mode of penetration and diffusion, NB-002 is able to achieve 50 times the minimum drug concentration required to kill the fungus in the very center of the nail bed. Only 4 micrograms per gram of tissue are required for NB-002 to kill fungal infections.

Newer, more effective therapies for nail fungus are important because onychomycosis remains a large unmet medical need, according to the NanoBio scientists. Oral systemic medications are plagued by serious hepatic and cardiac toxicity concerns, while current topical medications are not effective because they are unable to penetrate to the site of infection.

"The safe and efficient delivery of NB-002 ma
'/>"/>

Contact: Becky Levine
blevine@medthink.com
919-786-4918
MedThink Communications
Source:Eurekalert

0

GOOD

Page: 1 2

Related medicine news :

1. Topical treatment for cold sores achieves efficacy of oral drugs; represents paradigm shift
2. Topical oral syrup prevents early childhood caries
3. Nuvo licenses topical pain product from Paladin
4. Watson Announces Oxybutynin Topical Gel NDA Accepted for Filing by FDA for the Treatment of Overactive Bladder
5. Perrigo Company Announces Collaborative Agreement for Generic Topical Products With Pentech
6. Fougera First-to-Market With Calcipotriene Topical Solution 0.005% (Rx) (Scalp Solution)
7. ImQuest Presents New Anti-HIV Drug and Topical Microbicide Development Results on Lead Pyrimidinedione Products IQP-0410 and IQP-0528
8. Topical Cream Treats Precancerous Lesions of Vulva
9. ZARS Pharma Announces Worldwide License Agreement With Galderma Pharma S.A. for Pliaglis(TM), a Topical Local Anesthetic
10. International Federation of Sports Medicine Selects Celadrin(R) Topical Cream as its First and Only Official Joint and Muscle Topical Cream
11. Summit VetPharm Introduces New Feline Topicals Vectra(TM) for Cats & Kittens and Vectra(TM) for Cats
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2013)... In a coup that surely made other Palm ... the Estetica Institute of the Palm Beaches performed eye surgeries ... morning show, “The Mo & Sally Morning Show.” The DJ’s ... with the results, giving Dr. DeLange and the team at ... Gardens, very valuable free publicity. , Dr. DeLange, the owner ...
(Date:5/24/2013)... FL (PRWEB) May 24, 2013 The producers ... May air dates for Charlotte, North Carolina. It is one ... many Fortune 500 companies. The city is populated with more ... organizations which cover residents in both North and South Carolina. ... all things medically-related can tune into WAXN-TV 64 Eyewitness News ...
(Date:5/24/2013)... 24, 2013 Fit Yummy Mummy, a ... mothers who are trying to get rid of the ... is ideal for women who want to combine exercises ... ’s Stan Stevenson, prompting an investigative review. , ... contains a wide variety of motivational strategies, nutritional plans, ...
(Date:5/24/2013)... GA (PRWEB) May 24, 2013 CBT News.com ... Sales. Gonter joins the web-based retail automotive industry news organization ... , “I’m excited to join a group that’s so ... perfect example of how online video content is on the ... in the motorcycle business and segued into advertising at Cycle ...
(Date:5/24/2013)... Residents of San Diego have a new ... expert, and Certified Russian Kettlebell Instructor, Cody Bramlett has ... San Diego, California. The classes take place Monday through ... Initial sign-ups are available online and by clicking ... for years. The bootcamps being offered in San ...
Breaking Medicine News(10 mins):Health News:Dr. Greg DeLange of the Estetica Institute Recently Performed Eye Surgery on Both Members of Popular Morning Radio Team 2Health News:Health Briefs TV Presents May Air Dates for Charlotte, North Carolina 2Health News:Fit Yummy Mummy: Review Examining Holly Rigsby’s Fitness Program Released 2
... regulation of body weight suggests a potential mechanism underlying ... of two competing hypotheses of weight regulation. In ... General Hospital (MGH) investigators outline a system in which ... animal,s weight tends to gravitate, rather than a single ...
... R. Hill has been appointed,Interim President and CEO of ... to accept a position as president of HealthAmerica,s,Central Pennsylvania ... ) , Hill,s selection ... board of directors. , "The ...
... who allegedly was seriously injured by Medtronic, Inc.,s Infuse(R) ... by Medtronic has sued the company, according to James ... LLC.The firms, along with co-counsel Lieff, Cabraser, Heimann & ... on behalf of Paul and Susan Antonelli, of Amsterdam, ...
... too different from others , , WEDNESDAY, Jan. 14 ... go along with popular opinion in social situations, a ... resonance imaging showed that people whose opinion differed with ... response in the brain,s rostral cingulate zone (RCZ) and ...
... National Cancer Coalition (NCC) and Wyeth Pharmaceuticals (Wyeth) ... assist cancer patients in Latin America with donations ... injection) and Neumega(TM) (oprelvekin). United States Ambassador Michael ... a hand-over event held at the Instituto Nacional ...
... oust reformers, local union officers unopposedOAKLAND, Calif., Jan. ... Rosselli and all 17 other statewide officers were ... chair Debby Schneider. Their victory comes despite a ... to oust reformers in the local union from ...
Cached Medicine News:Health News:New model system may better explain regulation of body weight 2Health News:New model system may better explain regulation of body weight 3Health News:HealthPlus Names Bruce Hill Interim President and CEO 2Health News:Medtronic, Inc. and Medtronic Sofamor Danek USA, Inc. Sued for Product Liability and Promoting the Off-Label Use of Infuse(R) Bone Graft Product, According to Page Perry, LLC 2Health News:NCC and Wyeth Donation to Assist Cancer Patients in Latin America 2Health News:United Healthcare Workers Re-Elect All Statewide Officers 2
(Date:5/24/2013)... , May 24, 2013  An international roster ... Saturday, May 18, in Santa Monica, Calif. ... new lung-sparing therapies for MPM, a rare form of ... affects the pleura, the lining of the chest. ... and Blood Institute, the 3rd Annual International Symposium on ...
(Date:5/24/2013)... Corporation (NASDAQ: HSKA, "Heska" or the "Company"), a leading provider ... Robert Grieve , the Company,s chairman and ... executive vice president and chief financial officer, will present at ... May 30, 2013 in New York City ... Company,s presentation is scheduled to begin at 1:30 p.m. EDT. ...
(Date:5/24/2013)... 2013 China Biologic Products, Inc. (Nasdaq: CBPO, ... plasma-based biopharmaceutical company in China , ... a public announcement issued by Shanghai RAAS Blood Products ... Shenzhen Stock Exchange, that on May 21, 2013, Ms. ... one of the shareholders of the Company, and her ...
Breaking Medicine Technology:International Mesothelioma Experts Present Promising New Research Findings at the 3rd Annual International Symposium on Lung-Sparing Therapies for Malignant Pleural Mesothelioma 2International Mesothelioma Experts Present Promising New Research Findings at the 3rd Annual International Symposium on Lung-Sparing Therapies for Malignant Pleural Mesothelioma 3Heska Corporation To Present At The Second Annual Marcum LLP MicroCap Conference 2China Biologic Comments on the Proposed Shanghai RAAS Transaction 2China Biologic Comments on the Proposed Shanghai RAAS Transaction 3China Biologic Comments on the Proposed Shanghai RAAS Transaction 4
... SAN DIEGO, April 26, 2011 Cadence ... company focused on in-licensing, developing and commercializing proprietary products ... that the company,s President and CEO Theodore Schroeder will ... during the month of May: Deutsche ...
... 2011 Rochester Medical Corporation (NASDAQ: ROCM ) ... May 5, 2011.  The Company will then hold a quarterly ... begin at 3:30 p.m. central time (4:30 p.m. eastern time). ... can be accessed at Rochester Medical,s website at www.rocm.com ...
Cached Medicine Technology:Rochester Medical Announces Second Quarter 2011 Earnings Conference Call Thursday, May 5, 2011 2
... evaluation of pancreatic -cell function is not only ... of the natural history of diabetes mellitus, but ... guide to the correct choice of treatment. Peripheral ... function because of the large and variable uptake ...
... for the control of glucose metabolism. It ... of Langerhans as the precursor, proinsulin, which is ... are secreted in equimolar amounts into the portal ... of two polypeptide chains, the A-chain and B-chain ...
ENA Screen EIA Auto-Immune Markers 012-MDKES1 Extractable Nuclear Antigens...
Anti-PR3 EIA Auto-Immune Markers 013-PR3-48 Proteinase...
Medicine Products: