Navigation Links
New topical approach to treating nail fungus circumvents problems with current therapy
Date:10/28/2008

WASHINGTON, D.C. (October 27, 2008) A novel topical therapy for nail fungus, NB-002, has demonstrated a new topical approach to healing nail fungus by penetrating skin pores and diffusing through the skin that surrounds the entire nail plate, according to a study conducted by NanoBio Corporation.

The data represent a unique approach to treating nail fungus (onychomycosis), which resists topical therapies because they cannot penetrate the nail and access the site of infection. The results were reported this morning at the 48th annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)/Infectious Diseases Society of America (IDSA) 46th annual meeting in Washington, D.C.

"In testing NB-002 on human cadaver skin, we have demonstrated that the lotion permeates and then laterally diffuses across tissue plains in the epidermis and the dermis to more than 1 centimeter away from the site of application," said Susan Ciotti, Ph.D., director of formulations and research and development, and presenting author of the data.

"The average great toenail measures 22 millimeters across, so we are able to deliver NB-002 across the entire span of an infected human large toenail, a huge advance in the treatment of onychomycosis," Ciotti said.

Because of its novel mode of penetration and diffusion, NB-002 is able to achieve 50 times the minimum drug concentration required to kill the fungus in the very center of the nail bed. Only 4 micrograms per gram of tissue are required for NB-002 to kill fungal infections.

Newer, more effective therapies for nail fungus are important because onychomycosis remains a large unmet medical need, according to the NanoBio scientists. Oral systemic medications are plagued by serious hepatic and cardiac toxicity concerns, while current topical medications are not effective because they are unable to penetrate to the site of infection.

"The safe and efficient delivery of NB-002 ma
'/>"/>

Contact: Becky Levine
blevine@medthink.com
919-786-4918
MedThink Communications
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Topical treatment for cold sores achieves efficacy of oral drugs; represents paradigm shift
2. Topical oral syrup prevents early childhood caries
3. Nuvo licenses topical pain product from Paladin
4. Watson Announces Oxybutynin Topical Gel NDA Accepted for Filing by FDA for the Treatment of Overactive Bladder
5. Perrigo Company Announces Collaborative Agreement for Generic Topical Products With Pentech
6. Fougera First-to-Market With Calcipotriene Topical Solution 0.005% (Rx) (Scalp Solution)
7. ImQuest Presents New Anti-HIV Drug and Topical Microbicide Development Results on Lead Pyrimidinedione Products IQP-0410 and IQP-0528
8. Topical Cream Treats Precancerous Lesions of Vulva
9. ZARS Pharma Announces Worldwide License Agreement With Galderma Pharma S.A. for Pliaglis(TM), a Topical Local Anesthetic
10. International Federation of Sports Medicine Selects Celadrin(R) Topical Cream as its First and Only Official Joint and Muscle Topical Cream
11. Summit VetPharm Introduces New Feline Topicals Vectra(TM) for Cats & Kittens and Vectra(TM) for Cats
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... For Dr. Iris Hunter, a job is ... extension of her life’s mission. Her extensive experience in the ... of FirstLight HomeCare, make it clear that Hunter’s mission is ... my work makes a difference in the lives of others,” ... after much research, I felt ready to start on this ...
(Date:10/22/2014)... Angeles, California (PRWEB) October 22, 2014 Hay ... 2.0: Move Beyond Addiction and Upgrade Your Life (Paperback; $10.82) ... field of Yoga & Recovery. This book is meant ... thrive in a life of recovery. , Recovery 2.0 ... the 12 Steps; Recovery 2.0 is a guide for what ...
(Date:10/22/2014)... Losing Weight Your Body’s Way , In a ... the face, it certainly can be difficult to choose the ... extra favor by doing it the healthy way? Set aside ... to your body, exercise regularly, and choose foods with the ... weight; you need to exercise more and eat less. Despite ...
(Date:10/22/2014)... HealthDay Reporter , TUESDAY, Oct. 21, 2014 (HealthDay ... be showing a genetic propensity for obesity as toddlers, a ... linked to increased body fat, but the same genes in ... researchers said. At 1 year, kids with these genes ... however, these genes were linked to excessive weight gain, the ...
(Date:10/22/2014)... -- Measures taken by Firestone officials at the company,s ... limited the spread of the disease there and could ... Rubber Co. provides health services to about 80,000 employees, ... communities. Between Aug. 1 and Sept. 23, there ... 80,000 people. That incidence rate of 0.09 percent was ...
Breaking Medicine News(10 mins):Health News:Dr. Iris Hunter to Host Grand Opening of FirstLight HomeCare Tomorrow 2Health News:Hay House Announces The Official Release of Recovery 2.0: Move Beyond Addiction and Upgrade Your Life 2Health News:Hay House Announces The Official Release of Recovery 2.0: Move Beyond Addiction and Upgrade Your Life 3Health News:ReductionGuruMD Presents Ways to Improve Your Weight Loss Results 2Health News:Tall, Heavy 1-Year-Olds May Be at Risk for Obesity Later, Study Finds 2Health News:Tire Company Sets Standard for Ebola Care in Liberia: CDC 2
... By Jenifer Goodwin HealthDay Reporter , ... eight genes in the development of alopecia areata, a ... The genes are already associated with other autoimmune ... that drugs may already be in the pipeline that ...
... By Jenifer Goodwin HealthDay Reporter , WEDNESDAY, ... disease patients who received fetal cell transplants in the ... can prevent the troublesome side effect. The findings ... said. "These findings lend much optimism to new ...
... ... Unveils Military-Inspired Website on July 2nd to Expand Support of US Armed Forces and ... ... in performance apparel, footwear and accessories today announced the July 2nd launch of UA ...
... , WEDNESDAY, June 30 (HealthDay News) -- If you want to ... a new study suggests it might be a good idea to ... a link between exercise in adolescence and fewer cases of senility ... that exercise lowers the risk of dementia. And the research is ...
... (APS) ( www.aps.org ), a leading organization of ... Regulatory Commission (NRC) requesting the agency change its ... proliferation risks associated with smaller, more efficient nuclear ... the secret development of nuclear weapons, including incidents ...
... Researchers have identified a set of "molecular signatures" for ... liver transplant in children that can help identify ... outcomes. The Cincinnati Children,s Hospital Medical Center scientists ... only 14 of 47 infants with biliary atresia could ...
Cached Medicine News:Health News:Genes Tied to Hair Loss Disorder 2Health News:Genes Tied to Hair Loss Disorder 3Health News: Parkinson's Transplant Mystery Solved, Researchers Say 2Health News: Parkinson's Transplant Mystery Solved, Researchers Say 3Health News:Under Armour Launches UA Freedom Initiative in Celebration of Independence Day 2Health News:Under Armour Launches UA Freedom Initiative in Celebration of Independence Day 3Health News:Exercise May Guard Girls Against Dementia in Senior Years 2Health News:APS Physics files petition requesting NRC change licensing rules 2
(Date:10/22/2014)... DIEGO , Oct. 21, 2014   ... today the latest genomics research centers to purchase ... Salk Institute, the National Cancer Institute (NCI), NIH ... Sequencing Center). Before Irys, obtaining a comprehensive view ... next generation sequencing (NGS) does not deliver the ...
(Date:10/22/2014)... , Oct. 21, 2014 Influenza will affect ... deaths in the United States as ... are thought to spread is from person to person in ... has a serve way of death, but kills much fewer ... is also done by human fluids including sweat, saliva, blood ...
(Date:10/22/2014)... NEW YORK , Oct. 22, 2014 ... an August 2014 report by Global Research & Data ... 6.2% per year from 2014 through 2018, as demand ... United States is the world,s largest market ... market with advanced thermometers is Sanomedics International Holdings, Inc. ...
Breaking Medicine Technology:BioNano's Irys System Adopted by Leading Genomics Centers for Comprehensive Detection of Human Genome Structural Variation 2BioNano's Irys System Adopted by Leading Genomics Centers for Comprehensive Detection of Human Genome Structural Variation 3WholeHealth Products is proud to be releasing its Influenza A and B combo test, on the heels of the announcing of its phase 2 completion of the Rapid Ebola Test 2Sanomedics International Holdings Analyst Report: Taking Some Heat by BrokerBank Securities, Inc. 2
... CORDOVA, Calif., Jan. 23, 2012 ThermoGenesis Corp. (NASDAQ: ... services that process and store adult stem cells, said today, ... System from a new public cord blood bank that ... Canadian Blood Services, a national charitable organization that manages the ...
... (OTC.BB: SPIN.PK), a rapidly growing medical, management, billing and collection ... To Appear at Investor Conference January 23, ... with investors at the Southern California Investment Forum on January ... The Southern California Investment Forum is ...
Cached Medicine Technology:Canada's First National Public Cord Blood Bank Adopts ThermoGenesis BioArchive Cryopreservation System 2Canada's First National Public Cord Blood Bank Adopts ThermoGenesis BioArchive Cryopreservation System 3Canada's First National Public Cord Blood Bank Adopts ThermoGenesis BioArchive Cryopreservation System 4Spine Pain Management, Inc. Provides Corporate Updates 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: