Navigation Links
New tool helps doctors better predict, prevent deadly respiratory failure
Date:4/22/2014

A new prediction tool can help doctors better identify patients who are at highest risk for respiratory failure after surgery and therefore prevent the often deadly condition, suggest data from a large multi-center study published in the May issue of Anesthesiology.

Affecting nearly 200,000 Americans a year, acute respiratory distress syndrome (ARDS) is a sudden failure of the lungs caused by a number of issues ranging from smoke inhalation to pneumonia or blood infection. High-risk patients can develop ARDS after surgery. ARDS is difficult to treat once it develops and is fatal about 30 percent of the time.

Doctors may be able to take measures during surgery to prevent the condition, such as using blood products conservatively, restricting the volume of fluids administered and using different methods to ventilate the lungs. However, only about 3 percent of patients considered at risk actually develop ARDS and testing preventative measures is costly, time-consuming and may be less than ideal for patients not at high risk. Therefore, researchers in this study focused on identifying patients most likely to develop ARDS after surgery.

"It's certainly true in this case that an ounce of prevention is worth a pound of cure," said Daryl J. Kor, M.D., lead author of the study and associate professor of anesthesiology at Mayo Clinic, Rochester, Minn. "But our ability to predict who is at risk has been limited. By identifying those who are at highest risk with better accuracy, we can begin to take steps toward preventing this dangerous and costly surgical complication."

The prediction tool could help doctors assign risk levels to patients by determining if they have one or more of nine predictors identified as most associated with the development of ARDS: blood infection (sepsis), liver disease, high-risk surgery on the heart or aorta (the body's largest blood vessel), emergency surgery, admission from a location other than home (such as a nursing home or other hospital), an increased respiratory rate, and two measures that show the patient has lower-than-normal oxygen levels in the blood. The more factors that apply to the patient, the greater the risk of developing ARDS, and the more important it is to use preventive measures, Dr. Kor said.

In the study, researchers performed a secondary analysis of data from a trial at 22 medical centers, identifying 1,562 patients who prior to surgery were considered at risk for ARDS for example, those who had a blood infection or pneumonia. Of those, 117 (7.5 percent) actually developed ARDS. Based on their findings, researchers revised an existing prediction tool (used for ARDS prediction in a patients undergoing elective surgery) so it was far more effective at identifying patients who were at greatest risk for ARDS after a wide variety of surgical procedures.

"Previous efforts have largely focused on treating ARDS well after it's onset," said Dr. Kor. "There has not been a lot of success with that strategy. If the new prediction tool is validated by other studies, it could be used as a screening mechanism to identify patients at greatest risk for ARDS, thereby facilitating it's prevention as well as associated complications and death."


'/>"/>

Contact: Natalie Cammarata
n.cammarata@asahq.org
847-268-2252
American Society of Anesthesiologists
Source:Eurekalert  

Related medicine news :

1. Dustman protein helps bin cancer cells
2. New tool helps young adults with sickle cell disease in the transition to adult care
3. Anti-clotting agent helps reduce the incidence and impact of stent thrombosis during PCI
4. Treatment helps reduce risk of esophagus disorder progressing to cancer
5. Einstein helps establish $28 million consortium to find ebola treatment
6. Tequila plant is possible sweetener for diabetics -- helps reduce blood sugar, weight
7. Early detection helps manage a chronic graft-vs.-host disease complication
8. Tissue repair drug helps heal diabetic foot ulcers
9. Recycling of chauffeur protein helps regulate fat production
10. NIH scientists find mechanism that helps HIV evade antibodies, stabilize key proteins
11. Social Network Helps Dieters Lose Weight Socially and Earn Money
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New tool helps doctors better predict, prevent deadly respiratory failure
(Date:6/25/2016)... , ... June 25, 2016 , ... Conventional wisdom preaches ... success. In terms of the latter, setting the bar too high can result in ... than just slow progress toward their goal. , Research from PsychTests.com ...
(Date:6/24/2016)... ... 2016 , ... Marcy was in a crisis. Her son James, eight, was out of control. ... and physically. , “When something upset him, he couldn’t control his emotions,” remembers Marcy. ... rocks at my other children and say he was going to kill them. If ...
(Date:6/24/2016)... ... 24, 2016 , ... Comfort Keepers® of San Diego, CA is excited to ... Recovery® program to drive cancer patients to and from their cancer treatments. Comfort ... quality of life and ongoing independence. Getting to and from medical treatments is ...
(Date:6/24/2016)... ... June 24, 2016 , ... The ... recognize Dr. Barry M. Weintraub as a prominent plastic surgeon and the network’s ... the world, and the most handsome men, look naturally attractive. Plastic surgery should ...
(Date:6/24/2016)... ... June 24, 2016 , ... Venture Construction Group (VCG) ... held on June 20th at the Woodmont Country Club at 1201 Rockville Pike, Rockville, ... dedicated to helping service members that have been wounded in battle and their families. ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... Roche (SIX: RO, ROG; OTCQX: RHHBY) announced ... BRAHMS PCT (procalcitonin) assay as a dedicated testing solution ... this clearance, Roche is the first IVD company in ... sepsis risk assessment and management. PCT is ... levels in blood can aid clinicians in assessing the ...
(Date:6/23/2016)... 23, 2016 Bracket , a leading clinical ... generation clinical outcomes platform, Bracket eCOA (SM) 6.0, at ... 26 – 30, 2016 in Philadelphia , ... Outcome Assessment product of its kind to fully integrate with ... Bracket eCOA 6.0 is a flexible platform for electronic clinical ...
(Date:6/23/2016)... Revolutionary technology includes multi-speaker listening ... industry leaders in advanced audiology and hearing aid technology, ... ™, the world,s first internet connected hearing aid that ...      (Photo: http://photos.prnewswire.com/prnh/20160622/382240 ) , ... ,world firsts,: , TwinLink™ - the first ...
Breaking Medicine Technology: