Navigation Links
New tool helps doctors better predict, prevent deadly respiratory failure
Date:4/22/2014

A new prediction tool can help doctors better identify patients who are at highest risk for respiratory failure after surgery and therefore prevent the often deadly condition, suggest data from a large multi-center study published in the May issue of Anesthesiology.

Affecting nearly 200,000 Americans a year, acute respiratory distress syndrome (ARDS) is a sudden failure of the lungs caused by a number of issues ranging from smoke inhalation to pneumonia or blood infection. High-risk patients can develop ARDS after surgery. ARDS is difficult to treat once it develops and is fatal about 30 percent of the time.

Doctors may be able to take measures during surgery to prevent the condition, such as using blood products conservatively, restricting the volume of fluids administered and using different methods to ventilate the lungs. However, only about 3 percent of patients considered at risk actually develop ARDS and testing preventative measures is costly, time-consuming and may be less than ideal for patients not at high risk. Therefore, researchers in this study focused on identifying patients most likely to develop ARDS after surgery.

"It's certainly true in this case that an ounce of prevention is worth a pound of cure," said Daryl J. Kor, M.D., lead author of the study and associate professor of anesthesiology at Mayo Clinic, Rochester, Minn. "But our ability to predict who is at risk has been limited. By identifying those who are at highest risk with better accuracy, we can begin to take steps toward preventing this dangerous and costly surgical complication."

The prediction tool could help doctors assign risk levels to patients by determining if they have one or more of nine predictors identified as most associated with the development of ARDS: blood infection (sepsis), liver disease, high-risk surgery on the heart or aorta (the body's largest blood vessel), emergency surgery, admission from a location other than home (such as a nursing home or other hospital), an increased respiratory rate, and two measures that show the patient has lower-than-normal oxygen levels in the blood. The more factors that apply to the patient, the greater the risk of developing ARDS, and the more important it is to use preventive measures, Dr. Kor said.

In the study, researchers performed a secondary analysis of data from a trial at 22 medical centers, identifying 1,562 patients who prior to surgery were considered at risk for ARDS for example, those who had a blood infection or pneumonia. Of those, 117 (7.5 percent) actually developed ARDS. Based on their findings, researchers revised an existing prediction tool (used for ARDS prediction in a patients undergoing elective surgery) so it was far more effective at identifying patients who were at greatest risk for ARDS after a wide variety of surgical procedures.

"Previous efforts have largely focused on treating ARDS well after it's onset," said Dr. Kor. "There has not been a lot of success with that strategy. If the new prediction tool is validated by other studies, it could be used as a screening mechanism to identify patients at greatest risk for ARDS, thereby facilitating it's prevention as well as associated complications and death."


'/>"/>

Contact: Natalie Cammarata
n.cammarata@asahq.org
847-268-2252
American Society of Anesthesiologists
Source:Eurekalert  

Related medicine news :

1. Dustman protein helps bin cancer cells
2. New tool helps young adults with sickle cell disease in the transition to adult care
3. Anti-clotting agent helps reduce the incidence and impact of stent thrombosis during PCI
4. Treatment helps reduce risk of esophagus disorder progressing to cancer
5. Einstein helps establish $28 million consortium to find ebola treatment
6. Tequila plant is possible sweetener for diabetics -- helps reduce blood sugar, weight
7. Early detection helps manage a chronic graft-vs.-host disease complication
8. Tissue repair drug helps heal diabetic foot ulcers
9. Recycling of chauffeur protein helps regulate fat production
10. NIH scientists find mechanism that helps HIV evade antibodies, stabilize key proteins
11. Social Network Helps Dieters Lose Weight Socially and Earn Money
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New tool helps doctors better predict, prevent deadly respiratory failure
(Date:1/18/2017)... ... January 18, 2017 , ... Visually learn ... one doctor-recommended OTC antiperspirant, Certain Dri. , Excessive sweating and hyperhidrosis are common ... created this infographic to explain the seven types of hyperhidrosis. This visual creates ...
(Date:1/18/2017)... ... January 18, 2017 , ... The V Foundation for Cancer Research, ... official endurance training and fundraising team, to compete in the Boston Marathon on April ... to finish the world’s oldest annual marathon to join Team V and support the ...
(Date:1/18/2017)... Park, KS (PRWEB) , ... January 18, 2017 ... ... managed firm offering asset protection and financial planning services to families and business ... a charity event aimed at supporting children with developmental disabilities. , The Lakemary ...
(Date:1/18/2017)... ... January 18, 2017 , ... Michael J. Hennessy Associates, Inc., ... Center for Biosimilars, announced Michael J. Hennessy Associates, Inc. President Michael J. Hennessy, ... biosimilars through thought leader interaction in, live video and interactive digital platforms. , ...
(Date:1/18/2017)... VA (PRWEB) , ... January 18, 2017 , ... Floundering ... American Heart Month and the perfect time for a reset. The U.S. Apple Association ... studies to combat many of the factors that contribute to heart disease. , The ...
Breaking Medicine News(10 mins):
(Date:1/17/2017)... Jan. 17, 2017 Secretary of Health Dr. ... Secretary Gary Tennis are warning Pennsylvanians of ... recent overdose deaths from the drug in ... intended to sedate large animals and is not meant ... comes into contact with it," Secretary Murphy said. "It,s ...
(Date:1/17/2017)... Jan 17, 2017 Research and Markets ... Materials: 2017 - 2024" report to their offering. ... This new report revisits ... report that was issued in May of 2015. Self-healing is an ... our previous analysis we projected a market potential of $2.7 billion ...
(Date:1/17/2017)... The Global Nebulizers Market is poised to ... next decade to reach approximately $1698.68 million by 2025. ... witnessing include rapidly growing demand in emerging regions, increasing ... products and online marketing strategies by key players. ... into pneumatic nebulizers, ultrasonic nebulizers and mesh nebulizers. Pneumatic ...
Breaking Medicine Technology: