Navigation Links
New therapy for HIV treatment
Date:7/29/2008

Millions of people world-wide who have contracted a highly resistant strain of the HIV virus could benefit from a new drug to treat the infection.

Research co-authored by the University of New South Wales' (UNSW) National Centre in HIV Epidemiology and Clinical Research (NCHECR) shows that the majority of patients who have not responded to traditional treatments have had good results from a new combination therapy.

The drug raltegravir is already available in Australia and was listed on the Pharmaceutical Benefits Scheme on July 1st, with clinical trials showing that it is safe, effective and with minimal side-effects when used with other anti-HIV medicines.

The study, which has been published in the New England Journal of Medicine, shows the raltegravir effectively lowers the amount of virus in the blood to undetectable levels in 62 percent of people taking it in combination with other anti-HIV medicines.

Only one in three people who received a placebo plus other anti-HIV medicines had the amount of virus in the blood reduced to similar levels.

"This is the first drug in a new class of antiretroviral drugs called integrase inhibitors," said UNSW Professor David Cooper AO, the Director of NCHECR .

"The drug has a different mechanism of action, is very potent, seems very safe and has helped patients who have a virus that is resistant to older drugs and classes," said Professor Cooper.

"It initially will be used in developed countries, but hopefully, it will be made available at cheaper prices for patients in developing countries who are facing the same problems," said Professor Cooper.

The results were based on analyses of viral load reductions and CD4 cell count increases. A high CD4 cell count is crucial for a healthy immune system.

Professor Cooper said the efficacy shown at 48 weeks of treatment was consistent with observations at 24 weeks, indicating that the drug in combination has a durable effect.

The study shows the drug is well-tolerated by patients. It showed that only 0.9 percent of those receiving raltegravir discontinued therapy due to side-effects including nausea and headaches.


'/>"/>

Contact: Susi Hamilton
susi.hamilton@unsw.edu.au
61-293-851-583
University of New South Wales
Source:Eurekalert

Related medicine news :

1. Gentiva Safe Strides(R) Home Balance Therapy Program is Reducing Risk of Dangerous Falls and Relieving Pain for Thousands of Older Americans
2. Erectile dysfunction drugs allowed more chemotherapy to reach brain tumors in laboratory study
3. CSHL scientists correlate enzyme expression levels with chemotherapy drug response
4. D-cycloserine may improve behavioral therapy treatment for anxiety
5. Tx Xchange Launches Web-Based Solution for Physical Therapy and Rehabilitation Providers to Address Demands of Healthcare Consumerism
6. LSUHSC study finds high-dose HBO2 therapy extends survival window after cardiopulmonary arrest
7. Treating rare breast cancer with radiation therapy may lower recurrence rate
8. Medicare Modernization Act not associated with major changes in access to chemotherapy
9. Hormone Therapy Shows Little Benefit Against Prostate Cancer
10. Study points to cocktail therapy for Alzheimers
11. Global Med Technologies(R) Announces U.S. Release of Proven Tissue and Cellular Therapy Product
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/4/2016)... ... May 04, 2016 , ... DESCO ... acquired Pocono Sterilizer, an equipment sterilization service and sales company located in Pennsylvania. ... medical and research-related equipment and asset management services to the medical and academic ...
(Date:5/4/2016)... ... May 04, 2016 , ... ... their Vasont Universal Integrator (VUI) extension supports the latest release of Adobe FrameMaker, ... FrameMaker 2015 interlace the process of creating, editing and storing XML. ...
(Date:5/3/2016)... ... ... The National Association of Professional Women (NAPW) honors Barbara ... She is recognized with this prestigious distinction for leadership in business. NAPW is the ... over 200 operating Local Chapters. , “I’m pleased to welcome Barbara into this exceptional ...
(Date:5/3/2016)... ... May 03, 2016 , ... ... 2016 Champion Award to Charles D. Pulido, R.Ph., Co-Founder of NCPDP and member ... Ph.D., Pharmacy Advisor and Health IT Specialist, Office of the National Coordinator for ...
(Date:5/3/2016)... Irvine, California (PRWEB) , ... May 03, 2016 ... ... of its innovative brainsalvation tool – a web application that helps people assess ... medical research, the brainsalvation™ web app will provide users a “Risk Reduction Score™” ...
Breaking Medicine News(10 mins):
(Date:5/2/2016)... May 2, 2016 Kalorama Information noted the ... Records) market in a recent white paper.  The healthcare ... physician usage, a growing market are among the top ... Kalorama,s report EMR 2016: The Market for ... seventh complete study of the EMR industry, and the ...
(Date:5/2/2016)... N.J. , May 2, 2016  Celsion ... development company, today announced data from the first ... escalating clinical trial (the OVATION Study) combining GEN-1, ... care for the treatment of newly-diagnosed patients with ... followed by interval debulking surgery.  In the first ...
(Date:4/29/2016)... , April 29, 2016 ... Life Sciences, Product Development Capabilities in ... Customer Base . Indegene ( ... announced the acquisition of Skura Corporation,s life science ... in adaptive sales enablement technology for life science ...
Breaking Medicine Technology: