Navigation Links
New therapeutic options for diabetes-related tissue injury
Date:7/4/2008

Toronto, ON, Canada Diabetes mellitus is a metabolic disorder characterized by altered glucose tolerance and impaired lipid and carbohydrate metabolism, and is associated with a number of complications directly resulting from hyperglycemiainduced inflammation. Vascular changes in diabetes lead to increased risk of myocardial infarction and stroke due to atherosclerosis, retinopathy, end-stage renal disease, debilitating neuropathies, poor wound healing, enhanced risk of infection, and periodontal disease. Studies of diabetic complications suggest that activation of the inflammatory response is mediated in large part by phagocytic cells, macrophages, and polymorphonuclear leukocytes. Both cell types assume an aggressive proinflammatory phenotype resulting from hyperglycemia.

Today, during the 86th General Session of the International Association for Dental Research, investigators from Boston University report results from a study demonstrating that omega-6 and omega-3 fatty acids are precursors to a powerful new genus of anti-inflammatory and pro-resolution mediators, coined 'resolvins' and 'protectins'. These new local mediators counter-regulate pro-inflammatory signals and return tissues to homeostasis. These mediators reverse several of the proinflammatory functional responses of polymorphonuclear leukocytes and macrophages in vitro and prevent inflammation in a variety of animal models, and exhibit potential for new therapeutic options for resolving inflammation and tissue injury in diabetes.


'/>"/>

Contact: Linda Hemphill
lhemphill@iadr.org
International & American Association for Dental Research
Source:Eurekalert

Page: 1

Related medicine news :

1. Transition Therapeutics Announces Executive Management Appointments
2. Precision Therapeutics President and CEO Sean McDonald Named Ernst & Young Entrepreneur of the Year(R) 2008 Regional Award Winner
3. 2008 International Federation of Adipose Therapeutics and Science (IFATS) Conference Date Set
4. ExonHit Presents Therapeutic and Diagnostic Programs for Alzheimers at ICAD 2008
5. Medline Announces Advanced Line of Therapeutic Mattresses, Operating Room Table Pads and Stretcher Pads
6. Jerry Steffl Joins Prime Therapeutics as Vice President, Government Affairs
7. Fischman receives Pharmacology/Therapeutics/Toxicology Research Award
8. Lupin Enters Into Marketing Alliance with ASCEND Therapeutics for Suprax(R) 400 mg Tablets in the U.S.
9. Nuvelo Announces Publication of Preclinical Data From Wnt Therapeutics Program
10. Special supplement on self-monitoring of blood glucose in diabetes technology & therapeutics
11. Self-Monitoring of Blood Glucose Highly Effective in Diabetes Care, According to a Special Issue of Diabetes Technology and Therapeutics
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... The American ... to become its next President and Chief Executive Officer, succeeding Dr. James C. Puffer ... Elect beginning July 1, 2018 until Dr. Puffer’s retirement at the end of 2018. ...
(Date:10/13/2017)... ... October 13, 2017 , ... Apple Rehab Shelton Lakes , which specializes ... of the facility as part of a disaster drill on October 3rd. , Apple ... Shelton City Emergency Manager, as well as the Connecticut Long Term Care Mutual ...
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The ... the most popular and least understood books in the Holy Scriptures, Revelation. The Book ... have baffled scholars for centuries. Many have tossed it off as mere rubbish, but ...
(Date:10/12/2017)... ... October 12, 2017 , ... First Healthcare Compliance (FHC), ... will showcase a range of technology and learning solutions at the 68th Annual ... Expo to be held October 14–18, 2017 at the Mandalay Bay Resort in ...
(Date:10/12/2017)... ... October 12, 2017 , ... The American College of ... Carol Friedman, PhD, FACMI, during the Opening Session of AMIA’s Annual Symposium in Washington, ... In honor of Morris F. Collen, a pioneer in the field of medical informatics, ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... 2017  True Health, a leader in integrated ... during National Breast Cancer Awareness month to educate ... Research recently published ... more than 10 million American women are at ... or BRCA2 and have not had testing. These mutations ...
(Date:10/7/2017)... 2017   Provista, a proven leader in ... in purchasing power, today announced a new resource area ... Newsroom is the online home for case studies, ... bios, news releases, slideshows and events. ... of resources at their fingertips, viewers can also watch ...
(Date:10/4/2017)... LAWRENCE, Mass. , Oct. 4, 2017 /PRNewswire/ ... developer of single-use, self-contained, illuminating medical devices, today ... National Health Surveillance Agency (or Agência Nacional ... ®. The first single-use, cordless surgical retractor with ... ONETRAC provides optimal access, illumination and exposure of ...
Breaking Medicine Technology: