Navigation Links
New therapeutic options for diabetes-related tissue injury
Date:7/4/2008

Toronto, ON, Canada Diabetes mellitus is a metabolic disorder characterized by altered glucose tolerance and impaired lipid and carbohydrate metabolism, and is associated with a number of complications directly resulting from hyperglycemiainduced inflammation. Vascular changes in diabetes lead to increased risk of myocardial infarction and stroke due to atherosclerosis, retinopathy, end-stage renal disease, debilitating neuropathies, poor wound healing, enhanced risk of infection, and periodontal disease. Studies of diabetic complications suggest that activation of the inflammatory response is mediated in large part by phagocytic cells, macrophages, and polymorphonuclear leukocytes. Both cell types assume an aggressive proinflammatory phenotype resulting from hyperglycemia.

Today, during the 86th General Session of the International Association for Dental Research, investigators from Boston University report results from a study demonstrating that omega-6 and omega-3 fatty acids are precursors to a powerful new genus of anti-inflammatory and pro-resolution mediators, coined 'resolvins' and 'protectins'. These new local mediators counter-regulate pro-inflammatory signals and return tissues to homeostasis. These mediators reverse several of the proinflammatory functional responses of polymorphonuclear leukocytes and macrophages in vitro and prevent inflammation in a variety of animal models, and exhibit potential for new therapeutic options for resolving inflammation and tissue injury in diabetes.


'/>"/>

Contact: Linda Hemphill
lhemphill@iadr.org
International & American Association for Dental Research
Source:Eurekalert

Page: 1

Related medicine news :

1. Transition Therapeutics Announces Executive Management Appointments
2. Precision Therapeutics President and CEO Sean McDonald Named Ernst & Young Entrepreneur of the Year(R) 2008 Regional Award Winner
3. 2008 International Federation of Adipose Therapeutics and Science (IFATS) Conference Date Set
4. ExonHit Presents Therapeutic and Diagnostic Programs for Alzheimers at ICAD 2008
5. Medline Announces Advanced Line of Therapeutic Mattresses, Operating Room Table Pads and Stretcher Pads
6. Jerry Steffl Joins Prime Therapeutics as Vice President, Government Affairs
7. Fischman receives Pharmacology/Therapeutics/Toxicology Research Award
8. Lupin Enters Into Marketing Alliance with ASCEND Therapeutics for Suprax(R) 400 mg Tablets in the U.S.
9. Nuvelo Announces Publication of Preclinical Data From Wnt Therapeutics Program
10. Special supplement on self-monitoring of blood glucose in diabetes technology & therapeutics
11. Self-Monitoring of Blood Glucose Highly Effective in Diabetes Care, According to a Special Issue of Diabetes Technology and Therapeutics
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/5/2016)... ... 05, 2016 , ... Augusta Public Schools has teamed with CareDox to provide ... school health offices to streamline and bolster care for district students. , Augusta ... Augusta public schools serve 2,300 students among its six schools. , Monica Guilliams, ...
(Date:5/5/2016)... (PRWEB) , ... May 05, 2016 , ... ... the 1,000,000 mark for blood and service orders. Blood suppliers and their ... logistics. , “BloodHub serves 13,000 active users across 2,100 hospitals who use ...
(Date:5/4/2016)... ... May 04, 2016 , ... ProList is a set ... X . With ProList, editors can easily create lists for presentations, youtube productions, ... additional bullet points. ProList is the perfect complement to presentation style videos. , ...
(Date:5/4/2016)... ... May 04, 2016 , ... Mother Nature isn’t the only mom ... fruits and vegetables. , Celebrate these women with more than just a bouquet ... with these five garden-themed options. , Vibrant, Edible, Compact Plants from BrazelBerries: , ...
(Date:5/4/2016)... ... May 04, 2016 , ... The manufacturer of ... innovative kicking trainers to St. Jude Children’s Research Hospital to benefit families dealing ... rubber band designed to teach children how to kick a soccer ball correctly. ...
Breaking Medicine News(10 mins):
(Date:5/4/2016)... DUBLIN , May 4, 2016 /PRNewswire/ ... the addition of the  "Global Acute Ischemic ... 2016"  report to their offering.  ... Global Acute Ischemic Stroke Market ... insights into Acute Ischemic Stroke pipeline products, ...
(Date:5/3/2016)... 3, 2016 BioNovus Innovations LLC and ... Advancing Medical Innovation (IAMI) today announced a new ... and medical devices. An agreement between ... to license, develop and commercialize medical innovations advanced ... "This partnership represents a significant advance in our ...
(Date:5/3/2016)... May 3, 2016   BIOTRONIK , a ... announced Food and Drug Administration (FDA) approval of ... provides heart failure patients with access to diagnostic ... have remote monitoring with daily automatic transmission and ... rate in response to physiological demands. ...
Breaking Medicine Technology: