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New test may predict spread of breast cancer
Date:3/24/2009

endent of other currently used predictors, including lymph node metastasis, tumor size, presence of lymphovascular invasion, and tumor grade.

While the new test promises to reduce overtreatment of breast cancer, it could reduce undertreatment as well. There are some patients with Grade 1 breast cancer who ultimately develop metastatic disease, says Dr. Condeelis. By measuring TMEM counts, we could identify those people and treat them appropriately.

The researchers are currently working on a blood test for predicting metastatic breast cancer. In theory, such a test could predict the risk of metastatic disease even before a tumor forms. It could be part of a routine checkup, especially for women with a strong family history of the disease, says Dr. Condeelis. Before such a blood test could be developed for commercial use, researchers will need to conduct a population study.

The paper, TMEM in Human Breast Carcinoma: A Potential Prognostic Marker Linked to Hematogenous Dissemination, was published March 24th, 2009 in the online version of Clinical Cancer Research.

In addition to Dr. Condeelis, the co-authors of the paper include: Brian D. Robinson, Gabriel L. Sica, Yi-Fang Liu, Joan G. Jones of NewYork-Presbyterian Hospital/Weill Cornell Medical Center; Frank B. Gertler of Massachusetts Institute of Technology; and Thomas E. Rohan, professor of epidemiology and population health at Einstein.


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Contact: Deirdre Branley
dbranley@aecom.yu.edu
718-430-2923
Albert Einstein College of Medicine
Source:Eurekalert  

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