Navigation Links
New test for patients with sore throats cuts antibiotic use by nearly a third
Date:11/8/2013

A new 'clinical score' test for patients with sore throats could reduce the amount of antibiotics prescribed and result in patients feeling better more quickly, research in the British Medical Journal shows.

Researchers at the University of Southampton, funded by the National Institute for Health Research (NIHR) Heath Technology Assessment (HTA) Programme, used the five-item FeverPAIN score to decide whether to prescribe patients with an antibiotic immediately or to give them a delayed prescription and compared it with simply offering a delayed prescription.

The FeverPAIN score includes; fever in the past 24 hours, a pus infection, rapid attendance (within three days), inflamed tonsils and no cough or cold symptoms.

Results showed that using the test reduced antibiotic use by almost 30 per cent and despite using fewer antibiotics, patients in the FeverPAIN score group experienced a greater improvement in symptoms.

But the use of an in-practice rapid antigen test (a test which detects the bacteria, Lancefield Group A Streptococcus, which is the most common bacterium to cause sore throats) in conjunction with the FeverPAIN score did not result in any further reductions in antibiotic use or improvements in symptoms.

Paul Little, Professor of Primary Care Research who led the research, comments: "Our findings show that using this clinical score test can target antibiotics more effectively and help persuade patients antibiotics are not needed.

"Additionally the FeverPAIN score should enable better targeting of antibiotics than the current scoring system to identify the likelihood of a bacterial infection in patients complaining of a sore throat, as it allows GPs to rule out likely streptococcal infection in more patients."

The study recruited 631 patients with an acute sore throat and compared use of the FeverPAIN clinical score, with or without rapid antigen testing, with a delayed prescription, in which patients were told to pick up a prescription three to five days later if their symptoms did not settle or got worse.

Patients who had four or five of the clinical features of the FeverPAIN test were prescribed antibiotics immediately; a delayed antibiotic prescription was offered to patients with two or three features and no antibiotics to those with only one or no features.

The test led to a 29 per cent reduction in antibiotic use compared with the delayed prescription approach. One in three patients in the FeverPAIN score group said their sore throat had improved rapidly from a moderately bad problem to a slight problem within two to four days. Moderately bad or worse symptoms also got better faster in the clinical score group.

However, the use of a rapid antigen test as well as the FeverPAIN test for patients who displayed streptococci symptoms did not offer any further improvements, with a 27 per cent reduction in antibiotic use as well as similar improvements in patients' symptoms.

Study co-author Dr Michael Moore, a GP and a reader in primary care research at the University of Southampton, adds: "Clinicians can consider using a clinical score to target antibiotic use for acute sore throat, which is likely to reduce antibiotic use and improve symptom control. There is no clear advantage in the additional use of a rapid antigen test.

"We found that the FeverPAIN score picks up bacterial throat infections more accurately than the current scoring system and importantly picks up larger numbers of patients who are at low risk of streptococcal infection giving the patient and the doctor the confidence not to use antibiotics. If you select those at the highest risk of streptococcal infection then antibiotics can be more targeted at the people who are most likely to get symptom benefit."


'/>"/>

Contact: Becky Attwood
r.attwood@soton.ac.uk
0238-059-5457
University of Southampton
Source:Eurekalert

Related medicine news :

1. Revisiting Prevention of Blood Clots in Chemotherapy Patients
2. FDA awards $2.25M grant to study immunosuppresive drug in high-risk patients
3. Allegheny Health Network Partners with Region’s EMS Providers to Advance Treatment of Heart Attack Patients
4. AGA publishes tool to help GIs manage HCV patients
5. Transgender patients have special needs in the ER
6. Medical Factoring and Finance Company Alleon Capital Partners Closes a Financing Facility with Lab Serving Dialysis Patients
7. Patients Experience Impairments Just One Year After Knee Replacement Surgery, According to New Kantar Health Research
8. Pleasure and pain brain signals disrupted in fibromyalgia patients
9. Patients “Self-Refer” To Practices With Health Care Transparency Tools
10. Weighing in: 3 years post-op bariatric surgery patients see big benefits, Pitt study says
11. ScribeAmerica and Ochsner Health System Partner to Provide Efficient, Cost Conscious Healthcare for Patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/26/2017)... ... 26, 2017 , ... Today, A' Design Awards & Competition ... Social Design Awards. , The 7th A' Social Design Award is open ... worldwide with realized projects and conceptual works. , The first phase of the ...
(Date:2/26/2017)... , ... February 26, 2017 ... ... a new technology standard in staffing, scheduling, and reporting for healthcare organizations. ... predict activity throughout the entire staffing process. StaffBridge technology improves staffing efficiency, ...
(Date:2/24/2017)... , ... February 24, 2017 , ... ... newly designed TaskMate Go. Core benefits and advantages built into the home office ... stylish, functional look and feel. Ability to gain the benefits embedded in the ...
(Date:2/24/2017)... ... February 24, 2017 , ... ... Liberty University, has officially announced the appointment of Peter A. Bell, DO, MBA, ... Osteopathic Medicine (LUCOM), beginning April 10. Dr. Bell comes to Liberty from ...
(Date:2/24/2017)... ... 2017 , ... The narrative in “ Signal 8: An Australian Paramedic’s Story ... his paramedic experiences. Schanssema describes the tragedies he saw, as well as his struggles ... , Schanssema, initially unsure of the career path he wanted to take, found fulfillment ...
Breaking Medicine News(10 mins):
(Date:2/27/2017)... Feb 27, 2017 Period October – December 2016 ... Operating result amounted to SEK -16.4 (-6.4) million Result after ... (-0.22) before and after dilution Cash flow from operating activities ... ... 0.4 (0.4) million Operating result amounted to SEK -39.5 (-29.5) ...
(Date:2/24/2017)... , Feb. 24, 2017 Research and ... Market Analysis & Trends - Industry Forecast to 2025" report ... ... a CAGR of around 23.8% over the next decade to reach ... the market estimates and forecasts for all the given segments on ...
(Date:2/24/2017)... 24, 2017 Research and Markets has announced the ... 2016" report to their offering. ... The latest research Dry eye Drugs Price Analysis and Strategies ... eye market. The research answers the following questions: ... their clinical attributes? How are they positioned in the Global Dry eye ...
Breaking Medicine Technology: