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New technology using florescent proteins tracks cancer cells circulating in the blood
Date:5/8/2014

s of other normal blood cells by ultrafast changing color of photosensitive proteins inside the cell in response to laser light," explains Dr. Galanzha.

In tumor-bearing mice, the researchers could monitor the real-time dynamics of circulating cancer cells released from a primary tumor. They could also image the various final destinations of individual circulating cells and observe how these cells travel through circulation and colonize healthy tissue, existing sites of metastasis, or the site of the primary tumor. "Therefore, the approach may give oncologists knowledge on how to intervene and stop circulating cancer cell dissemination that might prevent the development of metastasis," she says.

The approach might also prove useful for other areas of medicinefor example, tracking bacteria during infections or immune-related cells during the development of autoimmune disease.


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Contact: Mary Beth O'Leary
moleary@cell.com
617-397-2802
Cell Press
Source:Eurekalert  

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