Navigation Links
New technology allows scientists to capture and preserve cancer cells circulating in the bloodstream
Date:12/17/2012

Scientists from the RIKEN Advanced Science Institute in Japan and University of California Los Angeles report a new nanoscale Velcro-like device that captures and releases tumor cells that have broken away from primary tumors and are circulating in the bloodstream.This new nanotechnology could be used for cancer diagnosis and give insight into the mechanisms of how cancer spreads throughout the body. The device provides a convenient and non-invasive alternative to biopsy, the current method for diagnosis of metastatic cancer. It could enable doctors to detect tumor cells that circulate in cancer patients' blood well before they subsequently colonize as tumors in other organs. The device also enables researchers to keep the tumor cells alive and subsequently study them.

The device was developed by a team led by Hsiao-hua Yu from the RIKEN Advanced Science Institute in Japan and Hsian-Rong Tseng from the Department of Molecular and Medical Pharmacology at the University of California Los Angeles, in research published online today in the journal Advanced Materials.

Similar cell-capture devices have been reported but this technology is unique in that it is capable of catching the tumor cells with great efficiency and releasing them with great cell viability. Blood is passed through the device like a filter that contains a molecule capable of adhering to tumor cells like Velcro and separating them with efficiency ranging from 40% to 70%. The cancer cells are retained by tiny temperature-responsive polymer brushes inside the device. At 37 degrees Celsius, these polymer brushes stick to the tumor cells, but when cooled to 4 degrees Celsius, they release them, allowing scientists to examine the cells.

"Until now, most devices have demonstrated the ability to capture circulating tumor cells with high efficiency. However, it is equally important to release these captured cells, to preserve and study them in order to obtain insightful information about them. This is the big difference with our device." Explains Hsiao-hua Yu, who led the team that developed the technique to coat the device with polymer brushes.


'/>"/>

Contact: Juliette Savin
pr@riken.jp
81-048-462-1225
RIKEN
Source:Eurekalert  

Related medicine news :

1. Mechanical tissue resuscitation technology shows promise
2. New study identifies how information technology is used to solve global health challenges
3. Power generation technology based on piezoelectric nanocomposite materials developed by KAIST
4. Simulation technology allows users to safely practice phacoemulsification cataract surgery
5. The Casey Group's Sales Navigator Wins 2012 Best Mobility App in the New Jersey Technology Council's Mobile Application Competition
6. Swanson Health Products Introduces a New Alkalizing Drink Mix, Swanson® pH Balance Alka-Tone with Alka-Plex™ Technology
7. Miami Children’s Hospital Performs First Nerve Repair Surgery Using Avance® Nerve Graft Technology
8. FDA Approves SonixGPS Needle Guidance Technology for Vascular Access Procedures
9. IVR Technology Group Named Platimum VAR by TSYS
10. 3M™ Gripping Material Technology – Giving Golfers a Competitive Edge
11. Newer technology to control blood sugar works better than conventional methods
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New technology allows scientists to capture and preserve cancer cells circulating in the bloodstream
(Date:5/2/2016)... (PRWEB) , ... May 02, 2016 , ... In honor ... will offer an incentive to people who share their fitness journey on social media. ... premium first aid products, will award a $100 product voucher each week during May ...
(Date:5/2/2016)... ... , ... East Los Angeles dentist , Dr. Ramin Assili, is now ... receive any dental extraction treatment for $40 off the regular price. This promotion cannot ... lower price, patients can more easily afford extractions to eliminate teeth that are damaged ...
(Date:5/2/2016)... ... 02, 2016 , ... Dr. Rassouli, dentist in Orange County, CA ... the research, which was published in the “Journal of the American Geriatrics Society,” more ... million Americans have Alzheimer’s disease. The study found that dental problems may increase the ...
(Date:5/2/2016)... ... ... Pregnancy Awareness Month offers a great time to get familiar with the latest ... to have a baby, it’s best to get started before age becomes an issue,” ... & Pregnancy Organizer, written for women who plan on becoming pregnant to learn about ...
(Date:5/2/2016)... ... ... Dr. Jonathan Kulbersh of Carolina Facial Plastics isn’t surprised that Charlotte, NC, the city where ... 5 US Cities with the Highest Plastic Rates .” The other cities that made ... calculated using a survey by RealSelf and combining that data with the number ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... Mich. , April 28, 2016   ... . Diplomat Pharmacy, Inc. (NYSE: DPLO), the nation,s ... has signed a definitive agreement to acquire Valley ... Specialty Pharmacy ("TNH"), a leading specialty pharmacy that ... Van Nuys, California . In 2015, TNH ...
(Date:4/28/2016)... 28, 2016 Research and Markets ... Surgery Products Market 2016-2020" report to their offering. ... The global plastic surgery products market is ... the period 2016-2020. , ,The growing adoption of laser ... growth of the market. Lasers are used to treat ...
(Date:4/28/2016)... 28, 2016 ... Phillips und Stephen Schmidt ... ArisGlobal®, ein führender Anbieter cloudbasierter Softwarelösungen ... bekannt, dass neue Führungskräfte zum Team Sicherheit ... die vielfältige Erfahrungen mitbringen.  Dies wird die ...
Breaking Medicine Technology: