Navigation Links
New technique improves purity of medicines
Date:10/24/2007

Dutch researcher Roelof Mol has investigated possibilities for more accurately determining the composition of medicines. He came up with a combination of two techniques that were previously considered to be incompatible: the separation technique electrokinetic chromatography (EKC) and the detection technique mass spectroscopy (MS). He has used this approach to develop an extra quality control mechanism for the active ingredient and excipients in medicines. With this, the chance of a toxic substance ending up in a medicine will be reduced considerably.

Mol applied the combined technique he has developed to so-called impurity profiling, during which contaminants in pharmaceutical samples are analysed. It proved possible to measure contaminants in medicines to within the 0.1% (m/m) level, which means the method satisfies all of the official sensitivity requirements.

No more harmful side effects

The combined technique can also help to limit the harmful side effects of medicines. Many medicines consist of several forms that are, as it were, mirror images of each other. One of the mirror images is the active ingredient where as the other can cause side effects. The medicine Softenon is a well-known example of this. The active substance is thought to be harmless but the mirror image of this was possibly the cause of serious birth defects.

The standard technique for determining harmful contaminants in medicines is high pressure liquid chromatography (HPLC). Mol believes that his linking of the separation technique EKC to the detection technique MS is a very good alternative analysis technique for checking the composition of medicines. The sensitivity of the systems is good and it can be used for a wide range of medicines. Mol is not alone in his thinking. Two companies participating in the research, Solvay and Organon, have also expressed particular interest in the systems.

Besides decreasing harm to human lives this w
'/>"/>

Contact: Roelof Mol
roelof.mol@eu.astellas.com
Netherlands Organization for Scientific Research
Source:Eurekalert

Page: 1 2

Related medicine news :

1. PCR emerging as a promising technique for Diagnosing Urinary Tuberculosis
2. New Laser Techniques cure degeneration of the eye
3. Conventional pap smears techniques to detect cervical cancer are here to stay
4. Micro-camera provides new breast imaging technique
5. IVF technique May Increase The Risk Of Birth Defects
6. New technique to diagnose heart disease
7. Novel biopsy technique for prostate cancer
8. New technique for heart enlargement
9. Laser technique assists beard problem
10. Comparing Breast surgery techniques
11. Latest technique for asthma treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/20/2014)... Women’s health specialist, Dr. Amber Murphy, ... of Columbus, Inc., A Division of MaternOhio Clinical Associates, ... than 100,000 patients annually. Dr. Murphy will provide a ... of a women’s life. She is accepting new patients ... and Dublin. , Dr. Murphy offers a wide variety ...
(Date:10/20/2014)... Kennewick, WA (PRWEB) October 20, 2014 ... new workflow management software application. The new module ... ensure patients receive full life-cycle quality care. , This ... to others within their practice, attach a to-do item ... see fit, and even set up reoccurring reminders for ...
(Date:10/20/2014)... Oregon (PRWEB) October 20, 2014 Succeed is ... of local companies who participated in the Every Body ... is a public awareness project that encourages workers to be ... Summer Step 10,000 Program, which concluded at the end of ... variety of cities and metro areas. Participating companies gave ...
(Date:10/20/2014)... hard to imagine what it’s like to live without shoes, ... it’s a reality. And while new shoes are considered a ... barefoot on rocky terrain or sewage-lined streets just to collect ... , Buckner International's Shoes for Orphan Souls project ... encourage support for Air1 and while also providing new shoes ...
(Date:10/19/2014)... (PRWEB) October 20, 2014 The ... iPage ( http://www.top10bestseohosting.com/go/iPage/ ) and GreenGeeks are the ... excellent platforms for those who want to buy ... same time. , The IT manager of Top10BestSEOHosting.com ... the most recommended suppliers for everyone. A lot ...
Breaking Medicine News(10 mins):Health News:OhioHealth Welcomes New Women’s Health Specialist to MaternOhio Specialists in Obstetrics & Gynecology of Columbus, Inc. 2Health News:OhioHealth Welcomes New Women’s Health Specialist to MaternOhio Specialists in Obstetrics & Gynecology of Columbus, Inc. 3Health News:My Clients Plus Announces New Workflow Management Software 2Health News:Succeed Management Solutions, LLC Competes in Walking Challenge and Achieves 12th Place in Portland 2Health News:Buckner Shoes for Orphan Souls® Garners Support from Air1 Radio 2Health News:Buckner Shoes for Orphan Souls® Garners Support from Air1 Radio 3Health News:Top10BestSEOHosting.com Considers iPage And GreenGeeks As The Best Dedicated Server Hosting Suppliers 2
... Lunch Kill You?" Protest Shines Spotlight on Need for New Meat Regulations , ... , , ... ... WASHINGTON , March 18 ...
... High levels in men appear to be beneficial, study ... have found evidence that older men with higher levels ... or improper blood-sugar metabolism. , Tasnime Akbaraly, from the ... French adults for nine years, checking their levels of ...
... a new health education program to promote sound "mind and body" health practices among individuals who live with serious mental illness. , ... , ... ... ...
... who is a direct target of sexism, there are others ... of one sexist man affect how female bystanders feel and ... from the University of Connecticut in the US, publish their ... to sexism in Springer,s journal Sex Roles . ...
... ... Performance, Resilience, and Management. , ... Santa Clara, CA (PRWEB) March 18, 2010 -- NHS ... across the county, has completed the deployment of Aerohive Networks’ award-winning ...
... ... of Directive 98/79/EC on in vitro diagnostic medical devices. , ... Madison, WI (PRWEB) March 18, 2010 -- The Promega ... Directive 98/79/EC on in vitro diagnostic medical devices. The CE mark applies to the instrument, ...
Cached Medicine News:Health News:Victims of Contaminated Meat Call on USDA to Address Deadly Pathogens 2Health News:Victims of Contaminated Meat Call on USDA to Address Deadly Pathogens 3Health News:'Hearts and Minds' Promotes Wellness; African Americans Living with Mental Illness Have Higher Risk for Other Illnesses. 2Health News:'Hearts and Minds' Promotes Wellness; African Americans Living with Mental Illness Have Higher Risk for Other Illnesses. 3Health News:'Hearts and Minds' Promotes Wellness; African Americans Living with Mental Illness Have Higher Risk for Other Illnesses. 4Health News:'Hearts and Minds' Promotes Wellness; African Americans Living with Mental Illness Have Higher Risk for Other Illnesses. 5Health News:Cat-calls are detrimental to everyone 2Health News:NHS Lincolnshire Applies Intuitive ‘Cooperative Control' Wireless LAN 2Health News:NHS Lincolnshire Applies Intuitive ‘Cooperative Control' Wireless LAN 3Health News:Promega Maxwell 16 IVD System CE Marked to the European Union IVD Directive Delivers Combined Solution for Infectious Disease 2
(Date:10/20/2014)... , Oct. 20, 2014  Luoxis Diagnostics, Inc., ... AMPE), today announced that its academic collaborators will ... research potential for its novel RedoxSYS Diagnostic System, ... in the body in response to injury or ... ORP as a clinical marker will be presented ...
(Date:10/20/2014)... 2014   Taiho Oncology, Inc. , a ... Japan ), announced that the U.S. Food ... for TAS-102 (nonproprietary names: trifluridine and tipiracil hydrochloride), ... the treatment of refractory metastatic colorectal cancer (mCRC), ... NDA submission to the FDA. According to the ...
(Date:10/20/2014)... and RALEIGH, N.C., Oct. 20, 2014 /PRNewswire/ ... Neuropathy Foundation (HNF), both philanthropies, announced today the ... candidates for the treatment of the rare disease ... BioPontis Alliance announced its alliance model earlier this ... first demonstration of a collaborative model where researchers ...
Breaking Medicine Technology:Luoxis to Highlight RedoxSYS at Two Upcoming Scientific Conferences 2Luoxis to Highlight RedoxSYS at Two Upcoming Scientific Conferences 3Luoxis to Highlight RedoxSYS at Two Upcoming Scientific Conferences 4Luoxis to Highlight RedoxSYS at Two Upcoming Scientific Conferences 5Taiho Oncology, Inc. Receives FDA Fast Track Designation for TAS-102 as a Potential Treatment for Refractory Metastatic Colorectal Cancer 2Taiho Oncology, Inc. Receives FDA Fast Track Designation for TAS-102 as a Potential Treatment for Refractory Metastatic Colorectal Cancer 3Taiho Oncology, Inc. Receives FDA Fast Track Designation for TAS-102 as a Potential Treatment for Refractory Metastatic Colorectal Cancer 4The Hereditary Neuropathy Foundation and BioPontis Alliance for Rare Disease Partner to Develop Treatments for Charcot-Marie-Tooth 2The Hereditary Neuropathy Foundation and BioPontis Alliance for Rare Disease Partner to Develop Treatments for Charcot-Marie-Tooth 3
...  Cardinal Health, Detroit Medical Center (DMC) and Henry Ford ... to spur urban renewal and bring jobs to the ... ) As part of the economic recovery ... agreements with Cardinal Health, enabling the company to relocate ...
... 2012 Fluke Biomedical announced today the new ProSim ... test tool on the market to achieve the RoHS ... Hazardous Substances , RoHS regulations are designed to limit ... and to people. The RoHS E label certifies the new ...
Cached Medicine Technology:Cardinal Health, Detroit Medical Center, Henry Ford Health System Announce Unique Collaboration To Promote Urban Renewal 2Cardinal Health, Detroit Medical Center, Henry Ford Health System Announce Unique Collaboration To Promote Urban Renewal 3Cardinal Health, Detroit Medical Center, Henry Ford Health System Announce Unique Collaboration To Promote Urban Renewal 4Fluke Biomedical device first to achieve environmentally-friendly label 2
Rheumatoid factor screening...
An enzyme linked immunoassay (ELISA) for the detection and semiquantitation of IgG, IgA or IgM anticardiolipin antibodies, as an aid in assessing the risk of thrombosis in individuals with Systemic L...
The ImagingPlanet 70 mm surgical microscope video adapter: Superior optical quality and precise engineering make this 70 mm focal length adapter an excellent decision for use with your Leica surgica...
The ImagingPlanet 55 mm surgical microscope video adapter: superior optical quality and precise engineering make this 55mm focal length adapter an excellent decision for use with your Leica surgical ...
Medicine Products: