Navigation Links
New technique enables faster genetic diagnosis for hereditary diseases

Antwerp, Belgium − VIB researchers connected to the University of Antwerp have developed a new method that enables them to track down the cause of hereditary diseases more quickly and efficiently. By means of this technique, genetic tests that take a long time today − such as screening for hereditary forms of breast cancer − can be carried out much more rapidly. This finding creates new perspectives for tests that are currently expensive and difficult to perform.

Genetic screening today

Genetic screening is currently performed when, for example, several persons in a family contract the same disease. A member of the family may wonder whether it is in fact an hereditary disease, and, if so, whether he or she is a carrier and runs the risk of getting the disease or of transmitting it to his or her children. Following genetic advice, screening can be performed: whereby scientists investigate whether there is indeed a defect in the DNA of the patients in the family (provided they cooperate in the testing) or of the family member who is inquiring. On the basis of this screening, medical practitioners can provide advice regarding prevention or regarding prenatal diagnosis when the person desires to have children.

If the gene that can cause the disease is very large, or if there are several genes that can possibly lead to the disease, diagnostic centers must conduct a lot of labor-intensive studies. This results in long waiting times, with the consequences that the person inquiring remains in a state of uncertainty for a longer time, that any preventive treatment is delayed, that a desire to have children is postponed, or that children are born with a defective gene.

A new technology

Now, VIB researchers Dirk Goossens and his colleagues in Jurgen Del-Favero's research group have developed a new method, with which several pieces of DNA can be examined simultaneously, instead of one after the other. They have succeeded in joining together two powerful existing techniques − multiplex PCR and massive parallel sequencing − making it possible to screen all of a person's relevant hereditary matter at one time. Use of this parallel technology offers an affordable solution for molecular diagnostics of a large number of (sometimes commonly occurring) disorders.

A much quicker diagnosis

With this new technology, the molecular diagnosis of genetic diseases − such as breast cancer, cystic fibrosis, and hereditary deafness − will be carried out much faster and more cost-effectively. It takes 3 to 6 months to receive a result with the techniques that are currently in use. By comparison, the new method produces a result within only a few weeks. Moreover, not only are these tests run much more quickly, they are also very sensitive and provide a more detailed result.


Contact: Sooike Stoops
VIB (the Flanders Institute for Biotechnology)

Related medicine news :

1. New bone implant technology using techniques normally used to make catalytic converters
2. Washington, DC Plastic Surgeon Pioneers New Minimal-Scarring Technique
3. Angled gantry technique reduced breast radiation exposure by 50 percent
4. Latest Breast Imaging Techniques Offer New Views
5. New technique captures high-res images of full retina
6. Novel Techniques Offers New Freedom to Patients with Parkinson's Disease, Epilepsy, Dystonia, and Tremor
7. Miami's Soluna MD Introduces New Cosmetic Surgery Facelift Technique With Permalift
8. Technique Tracks Cancer-Killing Cells
9. Novel imaging technique reveals brain abnormalities that may play key role in ADHD
10. Stress Spikes as Economy Tanks - Psychologist Identifies Why Traditional Stress Management Techniques Dont Work, and Offers Radical New Approach
11. New technique to study the genetics of breast cancer
Post Your Comments:
(Date:11/25/2015)... ... November 25, 2015 , ... Since its ... comprehensive solutions involving adult stem cell therapies to patients with chronic degenerative medical ... name as a Registered Trademark (RTM). , Organizations are required to hold a ...
(Date:11/24/2015)... ... November 24, 2015 , ... Dr. Todd S. Afferica, a noted ... to many of his patients. Dr. Afferica now uses the BIOLASE WaterLase iPlus 2.0™ ... of time the doctor uses other traditional cutting tools, such as the scalpel and ...
(Date:11/24/2015)... ... , ... In an article published November 12th by Obesity News ... or are not eligible for bariatric surgery. The article explains that candidates for weight ... 100 pounds overweight, or have a BMI of 35 and over with at least ...
(Date:11/24/2015)... Salt Lake City, UT (PRWEB) , ... November 24, 2015 , ... ... according to Forbes Magazine. For a business, it is critical that the first impression ... of a business, they are not likely to buy anything or want to return. ...
(Date:11/24/2015)... ... 2015 , ... Cancer patients, survivors, caregivers, family members and ... taping of the next CURE Connections® video series on Saturday, Dec. ... at Georgetown University Hotel & Conference Center in Washington, D.C. , CURE Connections, ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... , November 24, 2015 ... --> adds Latest Guidebook for ... of 217 pages published in November 2015 to ... online business intelligence library at . ... of the fastest growing global economies with a ...
(Date:11/24/2015)... LONDON , November 24, 2015 ... platform for scientists - since it was launched just six ... collaboration, reference management and authoring platform for scientists - since ... One million references have been loaded on to F1000Workspace ... for scientists - since it was launched just six months ...
(Date:11/24/2015)... , November 24, 2015 st  Scientific ... North America (RSNA) taking place in Chicago ... Booth 1122, Hall A. --> st  Scientific Assembly and ... (RSNA) taking place in Chicago ... Hall A. --> Molecular Dynamics will present its revolutionary ...
Breaking Medicine Technology: