Navigation Links
New technique can help diagnose mesothelioma
Date:8/23/2009

A new technique may help clinicians hone in on a diagnosis in patients presenting with a pleural effusion of unknown cause.

The study, led by principal investigator Y.C. Gary Lee, Ph.D., appears in the September 1 issue of the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

"Pleural effusion, or the accumulation of fluid in the pleural cavity, can be maddeningly difficult to diagnose as a wide variety of malignant and benign causes exist," said Helen Davies, M.R.C.P., specialist registrar and research fellow at the Oxford Centre for Respiratory Medicine and Oxford University, lead author of the study. "One of the causes, malignant pleural mesothelioma, is a relatively rare cancer, but its incidence is rapidly increasing on a global scale".

Currently, the first-line test for mesothelioma in patients with a pleural effusion is pleural fluid cytology, but this test is not very sensitive. Dr. Davies and her colleagues undertook the study to determine whether there would be additional clinical benefit to looking at pleural fluid mesothelin, a protein released in high quantities into the pleural fluid of most patients with mesothelioma.

They obtained pleural fluid samples from 209 patients referred to a specialized respiratory clinic. Levels of soluble mesothelin were measured in all samples.

Their results demonstrated median pleural fluid mesothelin levels were over six times greater in patients with mesothelioma than in patients with metastatic carcinomas, and ten times greater than in patients with benign effusions.

Using mesothelin levels at a cut-off of 20nM, they found that it had an overall negative predictive value of 95 percent, meaning that a patient with a mesothelin level less than the cut-off of 20nM could be 95 percent confident they did not have malignant mesothelioma. There were 12 false positive results with metastatic adenocarcinomas accounting fo
'/>"/>

Contact: Keely Savoie
ksavoie@thoracic.org
212-315-8620
American Thoracic Society
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Mount Sinai first with new technique to prevent a major cause for heart-related stroke
2. Iterative reconstruction technique significantly reduces patient radiation dose during CT scans
3. Nonsurgical Technique Can Take Years Off the Appearance of Aging Eyes
4. Therapy Technique Cuts Divorce/Separation Rate By Nearly 50 Percent
5. Plastic Surgery Technique Might Ease Migraines
6. Penile Prosthesis Surgery Infection Rates Reduced With The No-Touch Technique By Dr. J. Francois Eid of Advanced Urological Care
7. New technique could sustain cancer patients fertility
8. New technique could save cancer patients fertility
9. Emerging Techniques Put a New Twist on Ankle Repair
10. HealthSource of Chicago: New Techniques for Back Pain Relief in Chicago
11. Researchers develop new and efficient breast biopsy technique
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/23/2014)... (PRWEB) November 23, 2014 The FDA ... in Common, **FDAnews On-Demand Webinar**, Dec. 11, 2014 ? ... , The FDA’s focus on promotional activities is no ... , Now they're looking at websites, Twitter, journal articles, ... calendar for Thursday, Dec. 11, for On-Demand access to ...
(Date:11/23/2014)... OH (PRWEB) November 23, 2014 Wright ... on behalf of Ohio and West Virginia residents who ... other health disorders due to drinking C8 contaminated ... In Parkersburg, West Virginia. According to the C8 complaints, ... they either worked or lived in at least one ...
(Date:11/23/2014)... November 23, 2014 Today Zane ... for small businesses, announced their new on demand ... of Employer-Provided Health Insurance. , According ... greatest financial risk facing most American families. It ... small and large, when it comes to recruiting ...
(Date:11/22/2014)... (PRWEB) November 23, 2014 A new ... its doors in the downtown Greenville area. Dr. Chelsea ... Greenville , decided to open her own clinic after ... results with the patients. , AlignLife believes that ... tools. With a focus on chiropractic care and rehabilitation ...
(Date:11/22/2014)... PrettyTailor , an outstanding dress company, has ... Customers can buy new dresses at its online shop ... website. , As a matter of fact, PrettyTailor specializes ... provides four types of wedding outfits, including bridesmaid dresses, ... It also provides a variety of occasion dresses, such ...
Breaking Medicine News(10 mins):Health News:FDAnews Announces The FDA is Watching: What Twitter, Tradeshows and TV Have in Common, On-Demand Webinar, Dec. 11, 2014 2Health News:FDAnews Announces The FDA is Watching: What Twitter, Tradeshows and TV Have in Common, On-Demand Webinar, Dec. 11, 2014 3Health News:FDAnews Announces The FDA is Watching: What Twitter, Tradeshows and TV Have in Common, On-Demand Webinar, Dec. 11, 2014 4Health News:FDAnews Announces The FDA is Watching: What Twitter, Tradeshows and TV Have in Common, On-Demand Webinar, Dec. 11, 2014 5Health News:40 C8 Lawsuit Claims Filed By Wright & Schulte LLC Alleged Serious Illness Due To C8 Contaminated Water In Ohio And West Virginia 2Health News:40 C8 Lawsuit Claims Filed By Wright & Schulte LLC Alleged Serious Illness Due To C8 Contaminated Water In Ohio And West Virginia 3Health News:40 C8 Lawsuit Claims Filed By Wright & Schulte LLC Alleged Serious Illness Due To C8 Contaminated Water In Ohio And West Virginia 4Health News:Zane Benefits, Inc. Announces New Webinar on The End of Employer-Provided Health Insurance Now Available On-Demand! 2Health News:AlignLife of Downtown Greenville is Now Open and Accepting New Patients 2Health News:Customers Are Welcome to Shop at PrettyTailor.com 2
... ... Floor Randolph, CHICAGO, April 15 (Photo: ... skeleton outfitted with 73 actual orthopaedic devices used ... or joint problems. Manny dramatically demonstrates medical advances ...
... ... Network, NEW YORK, April ... strategic and business-building,experience, has joined GHG Grey Healthcare Group in the newly ... a WPP company and one of the world,s leading,healthcare communications companies. Ms. ...
... WHAT: A new study reports that inner-city children with ... at levels below current air quality standards. The ... of outdoor pollution levels on asthma symptoms and ... by the National Institutes of Health (NIH) and ...
... cervical cancer cells missed by chemotherapy , , TUESDAY, April ... to radiation and chemotherapy improves results for patients with ... (RU-486, the so-called abortion pill) to chemotherapy kills ovarian ... the conclusions of two reports on new trends in ...
... the 11 Awards Presented is the Inaugural Randy Pausch, PhD Pilot ... ... April 15 The Pancreatic Cancer,Action Network ( http://www.pancan.org ) announced today ... cancer,research. The grant portfolio, topping $1 million in new grants, includes,four Pilot ...
... experts suggest, , , TUESDAY, April 15 (HealthDay News) -- ... after millions of American women stopped using hormone-replacement therapy ... black women. , In fact, the rates ... black women from 2002 through 2004, while they were ...
Cached Medicine News:Health News:Susan Byrne joins GHG Grey Healthcare Group as EVP, Strategy and Business Development, Europe, a Newly-Created Position 2Health News:Air pollution affects respiratory health in children with asthma 2Health News:Extra Drug Improves Rectal Cancer Treatment 2Health News:Extra Drug Improves Rectal Cancer Treatment 3Health News:The Pancreatic Cancer Action Network Announces Its 2008 Research Grant Awards Totaling Over $1 Million in New Research Funding 2Health News:The Pancreatic Cancer Action Network Announces Its 2008 Research Grant Awards Totaling Over $1 Million in New Research Funding 3Health News:The Pancreatic Cancer Action Network Announces Its 2008 Research Grant Awards Totaling Over $1 Million in New Research Funding 4Health News:Breast Cancer Unchanged in Black Women, Despite Drop in HRT Use 2Health News:Breast Cancer Unchanged in Black Women, Despite Drop in HRT Use 3
(Date:11/21/2014)... GABLES, Fla. , Nov. 20, 2014   ... to become the first U.S. commercial producer of Molybdenum-99 ... a contract with INVAP to design its ... Fla. Mo-99 is the parent isotope of ... medicine procedures worldwide. In 2012, Congress passed legislation making ...
(Date:11/21/2014)... , Nov. 21, 2014  Lexicon Pharmaceuticals, Inc. (Nasdaq: ... its previously announced underwritten public offering of $50,000,000 of ... shelf registration statement. The offering will consist of 49,751,244 ... of $1.005 per share.  Lexicon has also granted the ... additional shares of common stock.  All of the shares ...
(Date:11/18/2014)... 18, 2014 Respiratory Motion and IMI Co ... device and services providers in Japan ... Motion,s innovative respiratory depression monitor, the ExSpiron™. As part ... working together to connect the clinical community in promoting ... of bringing innovative medical devices and new technology to ...
Breaking Medicine Technology:Coqui RadioPharmaceuticals Inks Deal With INVAP 2Lexicon Announces Pricing Of Common Stock Offering 2Lexicon Announces Pricing Of Common Stock Offering 3Prominent Japanese Med Device Provider to be Respiratory Motion's Exclusive Partner for World's #2 Medical Market 2Prominent Japanese Med Device Provider to be Respiratory Motion's Exclusive Partner for World's #2 Medical Market 3Prominent Japanese Med Device Provider to be Respiratory Motion's Exclusive Partner for World's #2 Medical Market 4
... 14 Merrimack Pharmaceuticals,Inc. today announced that enrollment ... 100 patients that evaluates the safety and efficacy ... rheumatoid arthritis (RA). MM-093 is a,recombinant version of ... Phase 2 study is,being conducted at 20 centers ...
... Inc.,(Amex: ILE ) announced today the completion ... II/III Study IT-A-008 investigating the Isolagen,Therapy(TM) for the ... will be administered at seven clinical sites across ... Isolagen Therapy could hold great promise for the,treatment ...
Cached Medicine Technology:Merrimack Pharmaceuticals Completes Enrollment in a Phase 2 Study of MM-093 in Patients with Rheumatoid Arthritis 2Isolagen, Inc. Completes Enrollment in Isolagen Therapy(TM) Phase II/III Acne Scar Study 2Isolagen, Inc. Completes Enrollment in Isolagen Therapy(TM) Phase II/III Acne Scar Study 3
Omniseal TD mat. Reusable rubber mat for sealing PCR plates. 5 pk....
Inquire...
... heat-resistant, aluminum foil film designed for the ... minimizes evaportaion and vapor loss during thermal ... devices or mats. Its proprietary adhesive ... Compared to other aluminum foils, AlumaSeal ...
Microseal 'F' foil, seals plates for cold storage (or cycling >25l), disposable, pkg of 100...
Medicine Products: