Navigation Links
New technique alleviates painful bone metastases
Date:5/31/2013

CHICAGO, IL (May 29, 2013)A high-dose of ultrasound targeted to painful bone metastases appears to quickly bring patients relief, and with largely tolerable side effects, according to new research presented by Fox Chase Cancer Center scientists at the 49th Annual Meeting of the American Society of Clinical Oncology on Monday, June 3.

During the procedure, known as MR-guided focused ultrasound, doctors direct a concentrated beam of energy to specific nerve endings that are causing pain in bone metastases. These patients typically have a significant amount of discomforthalf of study participants rated their pain at least a 7 out of 10but within a handful of days, most said they felt significant relief.

Although Fox Chase patients received local anesthesia during the procedure, the most commonly reported side effect was painwhich can often be alleviated with additional anesthesia, says study author Joshua Meyer, MD, attending physician in the Radiation Oncology Department at Fox Chase. "That's temporary pain, which is gone as soon as the procedure is over," he says. "The whole reason we're doing the procedure is for the pain relief that comes afterwards. And that's relatively quickwe see a response by a day or so, and within three days of the procedure most patients are reporting a significant improvement."

Specifically, 67% of the 107 treated patients said their pain was "much improved" after the treatment, and that relief continued through the end of the three-month study. In comparison, among a group of 35 patients that received a "sham" treatmentthey entered the machine but did not receive the interventiononly 20% reported some pain relief, Meyer and his colleagues reported.

During the procedure, patients enter into an MRI machine, which allows clinicians to direct a cone of ultrasound energy at specific, targeted bone sites that are causing pain. The MRI also acts as a thermometer to measure the temperature deep within the body created by the high dose of energy, which generates enough heat to burn the nerve endings that are causing pain.

Although pain relief was durable until the end of the study at 90 days, it's not clear how much longer the pain relief lasts, says Meyer. "We've had reports of patients experiencing pain relief up to a year or more outside of the study."

Typically, patients with bone metastases are treated with radiation, which shrinks the bone cancer that is putting pressure on nerve endings, causing pain. This technique also treats the cancer (MR-guided focused ultrasound may not), but often takes weeks before patients experience pain relief, and not all will respond, says Meyer. In addition, others may not be eligible to receive additional radiation, if they have limited bone marrow function, for instance, he notes. The latest research didn't compare the effectiveness of the ultrasound technique to radiation, but the response to ultrasound appears "within the same ballpark of that in previous studies with radiation."

MR-guided focused ultrasound has been approved by the U.S. Food and Drug Administration, and is available at Fox Chase Cancer Center, as well as a handful of other facilities around the country.


'/>"/>

Contact: Diana Quattrone
diana.quattrone@fccc.edu
215-815-7828
Fox Chase Cancer Center
Source:Eurekalert

Related medicine news :

1. New MRI technique may predict progress of dementias
2. Detecting malaria early to save lives: New optical technique promises rapid and accurate diagnosis
3. New technique may help severely damaged nerves regrow and restore function
4. New Techniques May Improve Infant Heart Surgery
5. New surgical technique for removing inoperable tumors of the abdomen
6. New technique predictably generates complex, wavy shapes
7. Screening for breast cancer without X-rays: Lasers and sound merge in promising diagnostic technique
8. A marker in the lining of the lungs could be useful diagnostic technique for lung cancer screening
9. New technique could reduce number of animals needed to test chemical safety
10. Technique spots disease using immune cell DNA
11. Noninvasive imaging technique may help kids with heart transplants
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... 13, 2017 , ... The International Association of Eating Disorders ... for the field of eating disorders, announces the opening of early registration for ... Florida at the Omni Resort at ChampionsGate. , The annual iaedp™ ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... (SOP) alumni Hannah Randall, PharmD ‘17, and Jennifer Huggins, PharmD ’17, along ... updates for the primary prevention of cardiovascular diseases during the 15th Annual ...
(Date:10/13/2017)... ... October 13, 2017 , ... Apple Rehab Shelton ... staged a mock evacuation of the facility as part of a disaster drill on ... Echo Hose EMS and Shelton City Emergency Manager, as well as the Connecticut ...
(Date:10/13/2017)... RIDGE, N.J. (PRWEB) , ... October 13, 2017 , ... ... annual Holly Day Market. Featuring a collection of specialty vendors and unique items from ... of personalized and quality-focused health and wellness services offered by the VNA. The ...
(Date:10/13/2017)... Milford, NJ (PRWEB) , ... October 13, 2017 , ... ... weekend at scenic Alexandria Park in Milford, NJ. This free event, sponsored by ... and physical activity. The fun run is geared towards children of all ages; ...
Breaking Medicine News(10 mins):
(Date:9/28/2017)... Hill-Rom Holdings, Inc. (NYSE: HRC), will host its fiscal ... Friday, November 3, 2017, beginning at 7:00 a.m. (CDT) ... a.m. (CDT) / 9:30 a.m. (EDT). In ... guidance for 2018, Hill-Rom executives will also highlight the ... long-range financial outlook through 2020. ...
(Date:9/25/2017)... 2017  EpiVax, Inc., a leader in the ... today announced the launch of EpiVax Oncology Inc., ... therapeutic cancer vaccines. EpiVax has provided $500,000 in ... enabling technologies to the new precision immunotherapy venture. ... Oncology as Chief Executive Officer. Gad brings over ...
(Date:9/19/2017)... 2017   ZirMed Inc ., a recognized leader in ... it has been ranked #1 by its users for the ... 2017 User Survey. ZirMed was recognized as the top-ranked end-to-end ... medical centers over 200 beds and holds one of the ... survey history. ...
Breaking Medicine Technology: