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New study shows that a cough medicine ingredient could effectively treat prostate cancer
Date:12/18/2008

ommon practice is known as "off-label" prescription. Noscapine is increasingly being used off-label to treat a variety of cancers. Dr. Barken used noscapine to treat a handful of prostate cancer patients before retiring from clinical practice. Encouraged by the success of these treatments, his foundation funded the laboratory study being reported in the December 2008 edition of Anticancer Research.

As founder and medical director of the Prostate Cancer Research and Educational Foundation in San Diego, Dr. Barken is encouraging academic institutions to follow up this successful laboratory research with a human clinical trial. He has pioneered a web-based patient tracking system that will greatly reduce the cost of the trial while cutting the time necessary to complete the study. Using the web-based tracking system will also allow doctors outside the U.S. to enroll patients in the research.

Rogosnitzky, director of research at MedInsight Research Institute, points out the significant advantages that noscapine could present as a treatment for prostate cancer. "Noscapine is effective without the unpleasant side effects associated with other common prostate cancer treatments. Because noscapine has been used as a cough-suppressant for nearly half a century, it already has an extensive safety record. This pre-clinical study shows that the dose used to effectively treat prostate cancer in the animal model was also safe."

Hormone therapy and chemotherapy, along with radiation and surgery, are currently used to slow the progression of advanced prostate cancer. Side effects resulting from these treatments include impotence, incontinence, fatigue, anemia, brittle bones, hair loss, reduced appetite, nausea and diarrhea. No toxic side effects were observed in the laboratory study of noscapine.


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Contact: Dr. Israel Barken
drbarken@pcref.org
619-461-8181
MedInsight Research Institute
Source:Eurekalert

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