Navigation Links
New study pinpoints difference in the way children with autism learn new behaviors
Date:7/6/2009

Researchers from the Kennedy Krieger Institute and Johns Hopkins University School of Medicine have collaborated to uncover important new insights into the neurological basis of autism. Their new study, published in the journal Nature Neuroscience, examined patterns of movement as children with autism and typically developing children learned to control a novel tool. The findings suggest that children with autism appear to learn new actions differently than do typically developing children. As compared to their typically developing peers, children with autism relied much more on their own internal sense of body position (proprioception), rather than visual information coming from the external world to learn new patterns of movement. Furthermore, researchers found that the greater the reliance on proprioception, the greater the child's impairment in social skills, motor skills and imitation.

Previous research has shown that children with autism have difficulty with motor skills, which appears to be associated with abnormalities in how the brain learns motor actions. To study the models formed in the brain when children with autism learn a new movement, researchers measured patterns of generalization as 14 children with autism and 13 typically developing children learned to reach using a novel tool. They then examined how well children were able to generalize what they learned in two separate ways one that detected how much they relied on visual information to guide learning and one that detected how much they relied on proprioceptive information to guide learning.

"These findings can lead to important advances in methods for treating autism. Applying the knowledge gained in the current study, targeted interventions can be developed that enhance visuo-motor associations in children with autism as they learn new skills," said Dr. Stewart H. Mostofsky, study author and a pediatric neurologist in the Department of Developmental Cognitive Neurology at the Kennedy Krieger Institute. "If done early enough, this could help to improve development of motor, social and communicative skills in children with autism. Further, it could also improve their ability to understand social cues because the brain systems critical to forming internal models of behavior that guide our actions are also critical to developing an understanding of the meaning of those actions."

The study findings also provide support for observations from previous studies suggesting that autism may be associated with abnormalities in the wiring of the brain; specifically, with overdevelopment of short range white matter connections between neighboring brain regions and underdevelopment of longer distance connections between distant brain regions. The findings from this study are consistent with this pattern of abnormal connectivity, as the brain regions involved in proprioception are closely linked to motor areas, while visual-motor processing depends on more distant connections.

"These findings not only demonstrate why children with autism have difficulty learning motor skills, but also provide real insight into why these children have difficulty learning to interact with the world around them," said Dr. Reza Shadmehr, senior study author and Professor of Biomedical Engineering and Neuroscience at the John Hopkins University School of Medicine. "If the way their brain is wired is not allowing them to rely as much as typically developing children on external visual cues to guide behavior, they may have difficulty learning how to interact with other people and interpret the nature of other people's actions."

Potential next steps include the use of neuroimaging to investigate whether or not proprioceptive versus visual feedback is actually associated with abnormal patterns of structural and functional connectivity in the brain of children with autism. Additionally, researchers may study if patterns of motor learning can be altered to increase visual connections in specific regions of the brain. Through interventions such as cortical stimulation, biofeedback and behavioral approaches, researchers are looking to investigate if there is an improvement in children with autism's ability to rely on visual input to guide how they learn a range of behavioral skills.


'/>"/>

Contact: Megan Lustig
mlustig@spectrumscience.com
202-955-6222
Kennedy Krieger Institute
Source:Eurekalert

Related medicine news :

1. Penn study finds pro-death proteins required to regulate healthy immune function
2. New study shows promise in reducing surgical risks associated with surgical bleeding
3. Study, meta-analysis examine factors associated with death from heatstroke
4. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
5. Study says COPD testing is not measuring up
6. Preclinical study suggests organ-transplant drug may aid in lupus fight
7. Ability to cope with stress can increase good cholesterol in older white men, study finds
8. High alcohol consumption increases stroke risk, Tulane study says
9. Mailman School of Public Health study examines link between racial discrimination and substance use
10. Pitt study finds inequality in tobacco advertising
11. Stanford study highlights cost-effective method of lowering heart disease risks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2016)... ... April 28, 2016 , ... CastCoverz!, America’s #1 trusted brand ... country's oldest waterproof cast protector . As the largest one-stop, orthopedic shop, ... of daily, night, weatherproof and waterproof covers for most orthopedic devices, including but ...
(Date:4/28/2016)... (PRWEB) , ... April 28, 2016 , ... Cosmetic Town, ... website, cosmetictown.com . The forum section was recently revamped and upgraded to allow ... surgical techniques in use across the country. , According to the senior editor of ...
(Date:4/28/2016)... ... April 28, 2016 , ... ... has been collaborating with doctors and hospitals to make transformative changes in how ... leading cell therapy minds this week in discussing breakthroughs in cellular medicine to ...
(Date:4/28/2016)... ... ... USA Medical Card reminds us that May is National Stroke Awareness Month. According to ... of death in the United States; someone has one every 40 seconds. Annually, almost ... 65 years old. A stroke is when blood flow to the brain is blocked ...
(Date:4/28/2016)... (PRWEB) , ... April 28, 2016 , ... ... M.D. has been named a Top Doc in Physical Medicine and Rehabilitation by ... with Castle Connolly Medical, Ltd. by randomly surveying physicians and medical leadership across ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... N.J. , April 28, 2016   Acsis ... today announced that leading IT market research and advisory ... " in the IDC MarketScape: Worldwide Pharmaceutical Track and ... 2016).  The report provides an assessment of the capabilities ... track and trace software market. Logo - ...
(Date:4/27/2016)... April 27, 2016  Hologic, Inc. (Nasdaq: ... results for the fiscal second quarter ended March ... of $0.24 increased 41.2%, and non-GAAP diluted EPS ... increased 5.8% on a reported basis, and 6.3% ... "We posted another good quarter, highlighted by 14.6% ...
(Date:4/27/2016)... 27, 2016 Elekta today announced ... will be the focal point of seven scientific presentations ... Society for Radiotherapy & Oncology, taking place April 29 ... state-of-the-art radiotherapy system and a high-field MRI scanner with ... the patient,s anatomy in real time. The MR-linac is ...
Breaking Medicine Technology: