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New study looks at growth rates of lung cancers found by CT screening
Date:3/26/2012

OAK BROOK, Ill. Growth rates of lung cancers found by annual rounds of computed tomography (CT) screening are important for determining the usefulness and frequency of screening, as well as for determining the treatment. According to the latest report from the International Early Lung Cancer Action Program (I-ELCAP) published online in the journal Radiology, lung cancers diagnosed in annual repeat rounds of CT screening are similarboth in volume doubling time and cell-type distribution to those found in clinical practice.

"There was concern that cancers diagnosed in the screening context were somehow different than cancers found in routine practice, that they were not aggressive," said I-ELCAP principal investigator Claudia I. Henschke, Ph.D., M.D., professor of radiology at Mount Sinai School of Medicine in New York, N.Y. "We demonstrate here that they are quite similar."

The researchers reported that growth rates found in cancers detected in repeat rounds of annual CT screening are not significantly different from growth rates reported for cancers diagnosed in clinical practice in the absence of screening. Also, the frequencies of small-cell carcinoma and adenocarcinoma among all lung cancers have been reported to be approximately 20 percent and 50 percent, respectively, in the absence of screening. In repeat rounds of CT screening, these frequencies were nearly identical (19 percent and 50 percent).

Lung cancer is the leading cause of cancer death among men and women. The American Cancer Society estimates that in 2012, approximately 226,160 new cases of lung cancer will be diagnosed in the U.S. and 160,340 Americans will die from the disease.

CT screening has been found effective in detecting lung cancer at its earliest, most curable stage.

"This study shows that the cell types of cancer diagnosed in annual rounds of screening, as well as their growth rates, are quite similar to those that are found in
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Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America
Source:Eurekalert

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