Navigation Links
New study identifies potential vaccine to prevent gastritis, ulcer disease, gastric cancer
Date:2/2/2011

  • When delivered intranasally, vaccine was found to be more effective
  • Funding will support future clinical trials to test effectiveness in humans

PROVIDENCE, R.I. A new study led by researchers at Rhode Island Hospital in collaboration with the University of Rhode Island (URI) and EpiVax. Inc, a privately owned vaccine development company in Providence, RI, has identified a potential vaccine capable of reducing colonization of Helicobacter pylori (H. pylori) -- a known cause of gastritis, ulcer disease and cancer. Their findings appear online in advance of print in the journal Vaccine.

Because the colonization of H. pylori has far-reaching health consequences, it represents a significant public health challenge. Current treatments use multiple antibiotics in combination with acid suppression medications to eradicate it. Due to an increase in antibiotic resistance, it is now more difficult to eliminate, and the development of a vaccine as an alternative therapy is of increased interest.

Steven Moss, M.D., is a gastroenterologist at Rhode Island Hospital and lead author of the paper. Moss, who is also a professor of medicine at the Warren Alpert Medical School of Brown University, says, "Normal immune mechanisms fail to eradicate H.pylori, but some prophylactic and therapeutic vaccine strategies using a wide variety of H. pylori antigens have been reported to be successful. The literature, however, does not define the optimal choice of antigen or the best delivery method."

Through an animal model study, Moss and his colleagues utilized a gene-to-vaccine approach, incorporating multiple epitopes (a part of an antigen that is recognized by the immune system) and administered them both intranasally and intramuscularly. The results of the study suggest that when the vaccine was delivered intranasally it was more effective. Moss says, "We found that the multi-epitope vaccine ind
'/>"/>

Contact: Nancy Cawley Jean
njean@lifespan.org
Lifespan
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Despite Treatment, Employees with Depression Generate Higher Absentee Costs, According to Thomson Reuters Study
2. American Council on Exercise (ACE) Study Reveals Kettlebells Provide Powerful Workout in Short Amount of Time
3. TV drama can be more persuasive than news program, study finds
4. Study carried out into biological risks of eating reptiles
5. Neuroimaging study may pave way for effective Alzheimers treatments
6. Study finds racial gaps continue in heart disease awareness
7. Luth Researchs IndicatorEDG(TM) Study Finds Americans Hopes of Achieving Their Dreams Are Fading
8. First blinded study of venous insufficiency prevalence in MS shows promising results
9. Soothing infants with food focus of childhood obesity study
10. People with anxiety disorder less able to regulate response to negative emotions, study shows
11. American Heart Association Rapid Access Journal Report: Study Finds Racial Gaps Continue in Heart Disease Awareness, Low Knowledge of Heart Attack Warning Signs Among Women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2014)... 02, 2014 Humility of Mary Health Partners ... at St. Elizabeth Health Center, 1044 Belmont Ave. , The ... more than 200 common health problems as well as tips ... injury, and advice on when to seek medical attention. ... in the Youngstown Room; the evening session runs from 5:30 ...
(Date:9/2/2014)... is pleased to announce that the following papers ... the ESC Congress 2014, taking place in Barcelona, ... Ultrathin strut biodegradable polymer sirolimus-eluting stent versus ... (BIOSCIENCE): a randomised, single-blind, non-inferiority trial, Windecker et ... strut thickness, surface polymer, and drug release have ...
(Date:9/2/2014)... Researchers in New Delhi, India have published a ... exposed to asbestos-contaminated work clothes for just 3 months as ... report in a new article. Click here to read ... say their patient was diagnosed with mesothelioma after ... she had come in contact with her miner father’s dirty ...
(Date:9/2/2014)... Headaches, both chronic and acute ruin lives. ... family and friends, sleeping and just coping well with daily ... of disability worldwide. The medications prescribed for these conditions ... of these cases of headache and back pain are of ... will not detect and fix the cause. , When ...
(Date:9/2/2014)... 2014 B. E. Smith, the only ... has been retained to lead a national chief ... Hospital in Sioux Falls, S.D. The top executive ... has recently placed more than 900 healthcare executives into ... physician-owned healthcare provider and nationally recognized leader in patient-centered ...
Breaking Medicine News(10 mins):Health News:HMHP Offers ‘Health at Home’ Workshop 2Health News:The Lancet: European Society of Cardiology Congress 2014 media alert 2Health News:New Report Illustrates That Even Brief Asbestos Exposure Can Trigger Mesothelioma, According to Surviving Mesothelioma 2Health News:Physical Therapists in Houston Learn Pain Relief Techniques 2Health News:Sioux Falls Specialty Hospital Retains B. E. Smith to Recruit New CEO 2Health News:Sioux Falls Specialty Hospital Retains B. E. Smith to Recruit New CEO 3
... June 16 The famed nonprofit Los Angeles,Jewish Home ... program designed to address one of the major health ... Jewish Community Foundation,the largest manager of charitable assets for ... prevention and fitness program becomes part of the care,the ...
... 2008 Researchers at Ben-Gurion University of the Negev ... recognition system, tested at a Washington, D.C. hospital, that ... by motioning instead of touching a screen, keyboard or ... to a just released article. , The June article," ...
... from the Swedish medical university Karolinska Institute (KI) suggests that ... on if adults decide to have sex with persons of ... the individual,s unique experiences have the strongest influence on our ... in the world so far and was performed in collaboration ...
... injury-related deaths, the gap between black and white American ... at the Johns Hopkins Bloomberg School of Public Health. ... deaths among blacks ages 15 to 24 decreased, while ... in the June, 2008, edition of Injury Prevention ...
... partners, innovative use of Microsoft technology to exceed ... customer expectations and solve business problems., ... delivered exemplary solutions to customers, Microsoft Corp. today,announced ... Partner of the,Year Awards. The awards honor Microsoft ...
... PLM Based on Dassault Systemes, Newly,Introduced V6 Platform and Intercim,s ... ... PAUL, Minnesota, June 16 Intercim LLC, a global,leader in ... regulated industries and Dassault,Systemes (DS) (Nasdaq: DASTY; Euronext Paris: #13065, ...
Cached Medicine News:Health News:Los Angeles Jewish Home Institutes New Fall Prevention Program With Jewish Community Foundation Grant 2Health News:Los Angeles Jewish Home Institutes New Fall Prevention Program With Jewish Community Foundation Grant 3Health News:Gesture interface device developed by Ben-Gurion University of the Negev 2Health News:Racial disparities reduced in injury related mortality 2Health News:Microsoft Announces 2008 Partner of the Year Awards Finalists and Winners 2Health News:Microsoft Announces 2008 Partner of the Year Awards Finalists and Winners 3Health News:Microsoft Announces 2008 Partner of the Year Awards Finalists and Winners 4Health News:Microsoft Announces 2008 Partner of the Year Awards Finalists and Winners 5Health News:Microsoft Announces 2008 Partner of the Year Awards Finalists and Winners 6Health News:Microsoft Announces 2008 Partner of the Year Awards Finalists and Winners 7Health News:Intercim and Dassault Systemes Sign Memorandum of Understanding 2Health News:Intercim and Dassault Systemes Sign Memorandum of Understanding 3
(Date:9/2/2014)... , Sept. 2, 2014  Amgen ... the submission of a Marketing Authorization Application ... via the centralized procedure for talimogene laherparepvec ... with melanoma that is regionally or distantly ... administered as an intralesional injection that is ...
(Date:9/2/2014)... FRANCISCO, Calif. , Sept. 2, 2014   Veracyte, ... Bonnie H. Anderson , president and chief executive officer, ... Morgan Stanley Global Healthcare Unplugged Conference 2014 on Monday, September ... York . The live audio webcast and ... http://investor.veracyte.com . Please connect to the website at least ...
(Date:9/2/2014)... Redspin, Inc., a leading provider of HIPAA ... an IT security advisory specifically for senior executives in ... presiding over the most dynamic period in the history ... Redspin,s President and CEO. "The goal of our advisory ... understand why they need to elevate IT security to ...
Breaking Medicine Technology:Amgen Submits Marketing Authorization Application For Talimogene Laherparepvec To The European Medicines Agency 2Amgen Submits Marketing Authorization Application For Talimogene Laherparepvec To The European Medicines Agency 3Amgen Submits Marketing Authorization Application For Talimogene Laherparepvec To The European Medicines Agency 4Amgen Submits Marketing Authorization Application For Talimogene Laherparepvec To The European Medicines Agency 5Amgen Submits Marketing Authorization Application For Talimogene Laherparepvec To The European Medicines Agency 6Veracyte to Present at the Morgan Stanley Global Healthcare Unplugged Conference 2014 2
... importance of dedicated information management systems for radiation ... most recent version of its MOSAIQ® Oncology Information ... Systems Society,s 2012 conference (HIMSS12), Feb. 20-24, in ... comprehensive OIS that centralizes traditional radiation oncology, particle ...
... Feb. 16, 2012  Cardium Therapeutics (NYSE Amex: ... previously announced sale of 17,857,143 shares of its common ... of approximately $5.0 million, before deducting placement agent,s fees ... investors participating in the offering purchased the shares at ...
Cached Medicine Technology:Elekta Highlights Latest Version of MOSAIQ Oncology Information System at HIMSS12 Meeting 2Cardium Announces Closing of $5.0 Million Equity Financing 2Cardium Announces Closing of $5.0 Million Equity Financing 3
...
The Tew cranial/spinal retractor is designed for posterior fossa or intraspinal microsurgery where retraction is required. Clinical applications are: Posterior fossa microsurgery and intraspinal micr...
The Doro Halo retractor system is designed for all neurosurgical applications where retraction of the brain tissue and an armrest is required....
The Budde Halo brain retractor is designed for use in all intercranial procedures where retraction of delicate brain tissue is required....
Medicine Products: