Navigation Links
New study identifies best treatment for childhood epilepsy
Date:3/12/2010

PORTLAND, Ore. One of the oldest available anti-seizure medications, ethosuximide, is the most effective treatment for childhood absence epilepsy, according to initial outcomes published in this week's New England Journal of Medicine.

OHSU Doernbecher Children's Hospital is one of 32 comprehensive pediatric epilepsy centers nationwide selected to participate in this landmark clinical trial as part of the NIH Childhood Absence Epilepsy Study Group.

The study group compared three medications typically used to treat the most common childhood epilepsy syndrome, childhood absence epilepsy, which is characterized by frequent non-convulsive seizures that cause the child to stop what he or she is doing and stare for up to 30 seconds at time.

Prior to this study, there was no definitive evidence on which drug worked best.

"Much of our scientific understanding of childhood epilepsy care today comes from historical experience or studies involving adult patients with related, but not identical, conditions," explained Colin Roberts, M.D., OHSU Doernbecher's principal investigator for the study, assistant professor of pediatrics and neurology, and director of OHSU Doernbecher's Pediatric Epilepsy Program,

"This study is an important milestone in our understanding of childhood absence epilepsy. Never before have we been able to document in such a comprehensive, scientific fashion the best options to treat children with this condition."

The study group enrolled 453 children newly diagnosed with childhood absence epilepsy from July 2004 to October 2007. Study participants were randomly assigned to ethosuximide, valproic acid or lamotrigine. Drug doses were incrementally increased until the child was seizure-free. After 16 weeks of therapy, the researchers found ethosuximide and valproic acid were significantly more effective than lamotrigine in controlling seizures, with no intolerable side effects. They also deter
'/>"/>

Contact: Tamara Hargens-Bradley
hargenst@ohsu.edu
503-494-8231
Oregon Health & Science University
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Some older ER patients are getting the wrong medicines, U-M study finds
2. Pill Wont Shorten Your Life: Study
3. Pancreatic cancer study reveals mechanism initiating disease, in mice
4. Pancreatic Cancer Study Reveals Mechanism Initiating Disease, In Mice
5. Study Results Validate Shape-HF as Simplified, Portable Cardiopulmonary Exercise Testing System
6. Top 10 Pharmaceutical Company Awards Comprehensive Cardiac Safety Study to iCardiac
7. Study: Kidney disease a big risk for younger, low-income minorities
8. Study Predicts Half of Physician Continuing Education Will Be Online by 2016
9. H1N1 Flu Spreads Slower Than Seasonal Flu: Study
10. New study questions benefits of elective removal of ovaries during hysterectomy
11. Study finds cancer mortality has declined since initiation of war on cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/22/2014)... 2014) The International Communication Association will hold ... Washington. The theme of the 2014 conference will ... networked and digital society. , Featuring over 2,300 ... 2,200 Communication scholars representing over 40 countries, the ... conference in the world. This year,s conference features ...
(Date:4/22/2014)... 22, 2014Hemoglobin A1c is the standard measurement for assessing ... levels of A1c are typically measured every few months ... data-based model that accurately estimates A1c using self-monitored blood ... & Therapeutics ( DTT ), a peer-reviewed journal ... available free on the DTT website at ...
(Date:4/22/2014)... April 2014. The latest scientific advances and emerging therapies ... 2014, the main annual meeting of the Heart Failure ... Journalists will also hear breaking news on acute heart ... Failure, which is part of the main congress. , ... Greece, at the Megaron Athens International Conference Centre (MAICC). ...
(Date:4/22/2014)... at the University of Utah (U of U) has ... separate cases, U of U researchers and their colleagues ... Journal of Human Genetics . The software, Phevor (Phenotype ... unknown gene mutations by analyzing the exomes, or areas ... made, in individual patients and small families. , ...
(Date:4/22/2014)... Nearly 7 in 10 Americans support mandated coverage of ... by researchers at the University of Michigan Health System. ... age of 18 at home, and adults with private ... adults to support universal coverage of birth control medications, ... Journal of the American Medical Association ( JAMA ...
Breaking Medicine News(10 mins):Health News:International Communication Association to hold Annual Conference in Seattle, Washington 2Health News:The world's largest heart failure congress 2Health News:The world's largest heart failure congress 3Health News:Applying math to biology: Software identifies disease-causing mutations in undiagnosed illnesses 2Health News:Applying math to biology: Software identifies disease-causing mutations in undiagnosed illnesses 3Health News:More than two-thirds of Americans support mandated coverage of birth control in health plans 2
... BOULDER, Colo., Aug. 25 Bioelements has ... www.ro o m214.com ) to support research, ... and online initiatives. "Room 214 was chosen as our ... consumer behavior," said Callie Lushina, Vice President of Marketing for ...
... , , Says Damage ... , , WASHINGTON, Aug. 25 The ... ) board to remove CEO John Mackey as Chairman and to begin ... Foods, lead independent director, Dr. John Elstrott, yesterday afternoon. Citing the ...
... ... across the nation take a collective step to improve their health through exercise and increased ... that may unlock the secret to living longer and healthier lives. , ... Cambridge, MA (Vocus) August 25, 2009 -- This ...
... CINCINNATI, Aug. 25 HealthWarehouse.com, Inc. (OTC Bulletin Board: ... financial results for the second quarter ended June 30, 2009. ... heavy growth in prescription sales and pharmacy transfers. Gross margins ... quarter was $396,271. , , "Consumers are ...
... , LOUISVILLE, Colo., Aug. 25 According ... Reconstructive Surgery Journal , the official journal of the American ... to be a safe and effective treatment option for fat ... Lipo to be an enhanced fat removal and transfer system ...
... in unpasteurised food has been detected in unusually high ... with the condition pre-eclampsia. These results are important ... indicator of pre-eclampsia and may help scientists to understand ... Scientists at the University of Leeds took blood ...
Cached Medicine News:Health News:Bioelements Selects Room 214 as Their Social Media and Online Marketing Agency 2Health News:CtW Investment Group Calls for Whole Foods Board to Remove Chair and CEO John Mackey 2Health News:CtW Investment Group Calls for Whole Foods Board to Remove Chair and CEO John Mackey 3Health News:CtW Investment Group Calls for Whole Foods Board to Remove Chair and CEO John Mackey 4Health News:Aging Science Leaders to Gather During Active Aging Week to Encourage Discovery in Healthy Living and Longevity 2Health News:Aging Science Leaders to Gather During Active Aging Week to Encourage Discovery in Healthy Living and Longevity 3Health News:HealthWarehouse.com, Inc. Announces Second Quarter Financial Results; Revenues Increase Significantly Over Second Quarter 2008 2Health News:HealthWarehouse.com, Inc. Announces Second Quarter Financial Results; Revenues Increase Significantly Over Second Quarter 2008 3Health News:New Study Reveals VASER(R) Lipo to be the New Standard of Care for Body Contouring and Fat Transfer Procedures 2Health News:New Study Reveals VASER(R) Lipo to be the New Standard of Care for Body Contouring and Fat Transfer Procedures 3Health News:New link between pre-eclampsia and diet 2
(Date:1/14/2014)... (Nasdaq: LMNX ) today announced that it expects ... Monday, February 3, 2014. A press release announcing the results ... (Logo: http://photos.prnewswire.com/prnh/20100104/LUMINEXLOGO ) Management will ... financial results for the fourth quarter and twelve months ended ...
(Date:1/14/2014)... , Jan. 14, 2014 /PRNewswire-iReach/ -- Acumed,s new SLIC ... guide with accompanying instrumentation to place and insert the ... the soft tissue (e.g. ligament) repair or reconstruction as ... heals. (Photo: http://photos.prnewswire.com/prnh/20140114/MN45636 ) ...
(Date:1/14/2014)... , Jan. 14, 2014   Oligomerix, Inc. , a ... therapeutics for Alzheimer,s disease (AD) and related neurodegenerative disorders, ... Valhalla, NY as of January ... space at New York Medical College. Oligomerix, ...
Breaking Medicine Technology:Luminex Corporation Fourth Quarter Earnings Release Scheduled for February 3, 2014 2Luminex Corporation Fourth Quarter Earnings Release Scheduled for February 3, 2014 3Acumed introduces the Scapho-Lunate Inter Carpal (SLIC) Screw System 2Acumed introduces the Scapho-Lunate Inter Carpal (SLIC) Screw System 3Oligomerix Relocates Corporate Headquarters and Secures Additional Laboratory Space from New York Medical College 2
... 21, 2011 MicroAire Surgical Instruments ... for carpal tunnel syndrome.  MicroAire,s new device, called ... assembly that allows surgeons to treat carpal tunnel ... wrist – thereby avoiding full open-hand surgery through ...
... 2011 Seal Shield LLC today announced ... for the iPad.  The product has been designed specifically ... use in hospital settings. The Seal Shield ... which is resistant to liquids including blood and bleach. ...
Cached Medicine Technology:MicroAire Introduces New SlimLine™ ECTR Cannula 2
... time-consuming tasks and delivers consistently ... productivity and ensure testing accuracy ... offers automated reticulocyte counts and ... excellent sensitivity, specificity and efficiency ...
The Fathom Guidewire combines a nitinol hypotube distal segment with advanced microfabrication technology, creating a design that revolutionizes access of the most tortuous vasculature....
... bi-polar CryoCor CryoBlator Series of Cryoablation Catheters ... catheter design with the two-stage cooling system ... maximize the delivery of cryoenergy to the ... work together to create the transmural lesions ...
... 5 software, the latest from Quality ... management application designed specifically for implementing ... system. The superior design, functionality, security, ... tool for managing a quality program., ...
Medicine Products: