Navigation Links
New study finds resistant organisms at core of soft contact lens corneal infections
Date:1/28/2008

In 2006, Bausch & Lomb withdrew its ReNu with MoistureLoc contact lens solution because a high proportion of corneal infections were associated with it. Now in a new study from University Hospitals Case Medical Center, researchers show that these infections were fueled and made resistant to treatment by the formation of a highly resistant structure of microbial cells held together with a glue-like matrix material. Scientists call this conglomeration of cells biofilms.

Once they live in that type of state, the cells become resistant to lens solutions and immune to the bodys own defense system, said Mahmoud A. Ghannoum, Ph.D., director of the Center for Medical Mycology at University Hospitals Case Medical Center and senior investigator of the study which appears in the January 2008 issue of the journal Antimicrobial Agents and Chemotherapy. This study should alert contact lens wearers to the importance of proper care for contact lenses to protect against potentially virulent eye infections, he said.

Biofilms are a constellation of resistant organisms, Dr. Ghannoum said. They were suspected with the spate of infections in 2005-2006, but until this study, there were no data to prove this. This is the first in-vitro model for cornea keratitis infections caused by the fungus Fusarium, which was one of the main culprits in the ReNu with Moisture Loc cases, and another fungus called Candida albicans.

The researchers also discovered that the strain of fungus (ATCC 36031) used for testing the effectiveness of lens care solutions is a strain that does not produce biofilms as the clinical fungal strains do. Lens care solutions currently are tested against an old and rare genotype fungal strain obtained in the 1970s from a patient from Nigeria. The contact lens solutions, therefore, are effective in the laboratory, but fail when faced with strains in real-world situations. The multipurpose contact lens solutions cannot kill these germ
'/>"/>

Contact: George Stamatis
george.stamatis@uhhospitals.org
216-844-3667
University Hospitals of Cleveland
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Feds fund study of drug that may prevent radiation injury
2. Study examines self-expanding plastic stents in the treatment of benign esophageal conditions
3. Amalgam Fillings Dont Affect Childrens Brain Development, Says Study in ADA Journal
4. Amalgam fillings dont affect childrens brain development, says study in ADA Journal
5. Global Health and Business Leaders Announce 36-Month Effort to Expand Malaria Control in Africa; 3.5 Million Lives Could be Saved in Five Years, Study Finds
6. From Research to Practice: Healthfitness, Eastman Chemical Company Case Study Demonstrates Real-World Health Gains and Productivity Savings
7. Study raises questions about diagnosis, medical treatment of ADHD
8. Another Study Links Western Diet to Heart, Health Risks
9. Nerites Receives NIH Grant to Study Novel Treatment for Preventing Dangerous Bacterial Infections on Urinary Stents and Catheters
10. New Kaiser Permanente study fortifies caffeines link to miscarriage
11. Kaiser Permanente study shows link between caffeine and miscarriage
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/1/2014)... The "Antimicrobial Coatings Market by Type (Silver, ... Dioxide, and Zinc Omadine), Application (Indoor air/HVAC, Medical, ... Textiles, and others), & Geography (North America, Europe, ... to 2018" analyzes the Antimicrobial Coatings Market with ... the diverse geographical regions. , Browse 49 market ...
(Date:8/1/2014)... 1, 2014 (HealthDay News) -- Although many parents worry about ... a common choking hazard: food. Such was the ... cough after eating a handful of nuts. "At the ... if the coughing was related to his illness or choking," ... cold. A cashew had become lodged in his windpipe and ...
(Date:8/1/2014)... For years, proponents have praised breast-feeding as ... conducted by the Ohio State University, suggests that ... terms of their health and development, raising questions among ... their baby. So does this new research change the ... , chair of Pediatrics at Abington Memorial Hospital, not ...
(Date:8/1/2014)... 2014 (BRONX, NY) Scientists at Albert ... found that bacteria that aid in digestion help keep ... the journal Immunity , could yield new therapies ... of other disorders. , The research involved the intestinal ... of these microorganisms in promoting or preventing disease is ...
(Date:8/1/2014)... In today’s age, traditional learning methods are futile in ... methods need to be revamped, so that the necessary ... this age of the internet, online learning resources act ... management systems help in the planning, implementation, and assessment ... are proving to be very useful and this trend ...
Breaking Medicine News(10 mins):Health News:Antimicrobial Coatings Market Projected to Reach $2.9 Billion by 2018 – Report by MarketsandMarkets 2Health News:Antimicrobial Coatings Market Projected to Reach $2.9 Billion by 2018 – Report by MarketsandMarkets 3Health News:Antimicrobial Coatings Market Projected to Reach $2.9 Billion by 2018 – Report by MarketsandMarkets 4Health News:Food Is a Common Choking Hazard for Kids, Doctor Says 2Health News:Despite Recent Study, Abington Health Expert Encourages Breastfeeding 2Health News:Despite Recent Study, Abington Health Expert Encourages Breastfeeding 3Health News:'Normal' bacteria vital for keeping intestinal lining intact 2Health News:North America Learning Management System Market is Expected to Reach $5.13 Billion in 2018 - New Report by MicroMarket Monitor 2Health News:North America Learning Management System Market is Expected to Reach $5.13 Billion in 2018 - New Report by MicroMarket Monitor 3Health News:North America Learning Management System Market is Expected to Reach $5.13 Billion in 2018 - New Report by MicroMarket Monitor 4
... Dec. 13 (HealthDay News) -- In the aftermath of a ... the U.S. National Transportation Safety Board is recommending a nationwide ... devices, except in emergencies. According to media reports, the ... fatal pileup that occurred last year in Gray Summit, Mo. ...
... 14, 2011Caffeine is regarded by some as being a potent ... exercise performance. A range of expert opinions capture the scope ... in Journal of Caffeine Research , a quarterly peer-reviewed ... available online at www.liebertpub.com/jcr . Led by ...
... WASHINGTON -- A new Institute of Medicine report specifies ... Administration should require before allowing tobacco companies to sell ... of reducing the health risks of tobacco use. ... of a comprehensive strategy to lower tobacco-related death and ...
... an animal model is a difficult task, but Thomas ... Reporting in the Proceedings of the ... immunologists found that a specialized "human immune system" mouse model ... tick-borne infection known as relapsing fever, caused by the bacteria ...
... of its ongoing efforts to ensure safe, effective and ... joined the ABIM Foundation and eight other medical specialty ... choices by physicians and patients to improve health outcomes, ... dollars. The ACR will develop a list ...
... German . Compared to Neanderthals, modern humans have ... lobes and olfactory bulbs also suggest a combined use of ... of brain size is intimately linked to the evolution of ... independently evolved brains of roughly the same size but with ...
Cached Medicine News:Health News:U.S. Safety Board Urges Nationwide Ban on Drivers' Use of Cellphones 2Health News:New report identifies research needed on 'modified risk' tobacco products 2Health News:New report identifies research needed on 'modified risk' tobacco products 3Health News:Jefferson researchers mirror human response to bacterial infection and resolution in mice 2Health News:ACR in Choosing Wisely campaign to promote wise use of resources among physicians and patients 2Health News:Follow your nose 2
(Date:7/31/2014)... , Indien, August 1, 2014 ... BioQuiddity Inc. gaben heute bekannt, vor kurzem ... Anästhesieanwendungen zur Schmerzbehandlung nach chirurgischen Eingriffen eine ... Gebiet der Europäischen Union und weiterer europäischer ... versehene und mit Ropivacain gefüllte OneDose ReadyfusOR ...
(Date:7/31/2014)... MOUNTAIN VIEW, Calif., July 31, 2014 IRIDEX Corporation ... the second quarter and six months ended June 28, 2014.  ... quarter of 2014, up 15% from $9.2 million in the ... the first quarter of 2014. Revenues for the first six ... million in the first six months of last year. ...
(Date:7/31/2014)... July 31, 2014 Pharmacyclics, Inc. (the "Company") (Nasdaq: ... developments for the quarter ended June 30, 2014. ... 30, 2014 Revenue Total revenue for the quarter ended ... for the quarter ended June 30, 2013 primarily due to ... Total revenue for the six months ended ...
Breaking Medicine Technology:Cipla und BioQuiddity geben EU-Geschäftspartnerschaft für OneDose-ReadyfusOR zur Schmerzbehandlung nach chirurgischen Eingriffen bekannt 2Cipla und BioQuiddity geben EU-Geschäftspartnerschaft für OneDose-ReadyfusOR zur Schmerzbehandlung nach chirurgischen Eingriffen bekannt 3IRIDEX Reports 2014 Second Quarter, Six-Month Results 2IRIDEX Reports 2014 Second Quarter, Six-Month Results 3IRIDEX Reports 2014 Second Quarter, Six-Month Results 4IRIDEX Reports 2014 Second Quarter, Six-Month Results 5IRIDEX Reports 2014 Second Quarter, Six-Month Results 6IRIDEX Reports 2014 Second Quarter, Six-Month Results 7Pharmacyclics Reports Second Quarter 2014 Results 2Pharmacyclics Reports Second Quarter 2014 Results 3Pharmacyclics Reports Second Quarter 2014 Results 4Pharmacyclics Reports Second Quarter 2014 Results 5Pharmacyclics Reports Second Quarter 2014 Results 6Pharmacyclics Reports Second Quarter 2014 Results 7Pharmacyclics Reports Second Quarter 2014 Results 8Pharmacyclics Reports Second Quarter 2014 Results 9Pharmacyclics Reports Second Quarter 2014 Results 10Pharmacyclics Reports Second Quarter 2014 Results 11Pharmacyclics Reports Second Quarter 2014 Results 12Pharmacyclics Reports Second Quarter 2014 Results 13Pharmacyclics Reports Second Quarter 2014 Results 14Pharmacyclics Reports Second Quarter 2014 Results 15Pharmacyclics Reports Second Quarter 2014 Results 16Pharmacyclics Reports Second Quarter 2014 Results 17Pharmacyclics Reports Second Quarter 2014 Results 18Pharmacyclics Reports Second Quarter 2014 Results 19Pharmacyclics Reports Second Quarter 2014 Results 20Pharmacyclics Reports Second Quarter 2014 Results 21Pharmacyclics Reports Second Quarter 2014 Results 22Pharmacyclics Reports Second Quarter 2014 Results 23Pharmacyclics Reports Second Quarter 2014 Results 24Pharmacyclics Reports Second Quarter 2014 Results 25Pharmacyclics Reports Second Quarter 2014 Results 26Pharmacyclics Reports Second Quarter 2014 Results 27Pharmacyclics Reports Second Quarter 2014 Results 28
... PHILADELPHIA, Jan. 5, 2011 ERT (Nasdaq: ... of technology and services to the pharmaceutical, biotechnology and ... Suicide Severity Rating Scale) solution facilitates compliance with the ... entitled "Suicidality: Prospective Assessment of Occurrence in Clinical Trials." ...
... Jan. 5, 2011 Cell Biosciences, Inc., a ... science researchers, today announced the launch of the ... imaging products, the FluorChem® M MultiFluor system. This ... fluorescent Western blots with key ease-of-use features aimed ...
Cached Medicine Technology:eC-SSRS Solution from ERT Facilitates Compliance with New FDA Guidance on Suicidality Assessment in Clinical Trials 2eC-SSRS Solution from ERT Facilitates Compliance with New FDA Guidance on Suicidality Assessment in Clinical Trials 3Cell Biosciences Launches New Platform for Multiplex Western Blot Detection 2
... is powerful, lightweight, easy ... soft, durable foam silicone ... covered by machine washable ... headband easily adjusts to ...
... is powerful, lightweight, easy ... soft, durable foam silicone ... covered by machine washable ... headband easily adjusts to ...
Solarc surgical headlight is durable, comfortable, lightweight and delivers the bright, white light expected from a xenon system, but at a fraction of the cost....
View Mex-3 is designed for out-patient surgery, hospital rounds and house calls....
Medicine Products: