Navigation Links
New study confirms link between nonalcoholic steatohepatitis and liver cancer
Date:5/25/2010

A study conducted by researchers at the Cleveland Clinic finds that patients suffering from cirrhosis preceded by nonalcoholic steatohepatitis are at an equal risk of developing hepatocellular carcinoma than those who develop cirrhosis resulting from hepatitis C virus (HCV). Results of this study appear in the June issue of Hepatology, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases (AASLD).

The incidence of hepatocellular carcinoma (HCC) doubled in the United States between 1983 and 2002. It is currently considered the third leading cause of cancer deaths. The increasing incidence of HCC parallels the obesity epidemic. An estimated two-thirds of obese people have some form of fatty liver, including nonalcoholic steatohepatitis (NASH), which can progress to cirrhosis and subsequently HCC. According to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NASH affects 2% to 5% of Americans and ranks as one of the major causes of cirrhosis in the U.S., behind HCV and alcoholic liver disease.

The Cleveland Clinic team, led by Nizar N. Zein, M.D., evaluated a total of 510 patients, 315 with liver cirrhosis secondary to chronic HCV infection and 195 with NASH-induced cirrhosis, to compare the incidence of NASH-cirrhosis to HCV-cirrhosis, and to identify HCC risk factors in each group. Over a median follow-up time of 3.2 years after cirrhosis diagnosis, the yearly cumulative incidence of HCC was 2.6% per year in patients with NASH-cirrhosis compared to 4.0% per year in those with HCV-cirrhosis. These figures suggest that NASH carries a risk of HCC that rivals the risk in patients with HCV-cirrhosis.

Results indicate three factors that are statistically significant in the development of HCC within the NASH-cirrhosis group. An older age at time of cirrhosis diagnosis and a higher BMI were negatively associated with the development of HCC. Among the
'/>"/>

Contact: Dawn Peters
medicalnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Center for the Study of Aging established at University of Denver
2. Heart Drugs Safe for Lungs, Study Finds
3. New national study examines pediatric mobility aid-related injuries
4. Insightful Case Study Details How Electronic Payment Exchange Saved a Global Firm More Than $3 Million in PCI-Related Costs
5. Fat in Males, Females Differs Genetically, Mouse Study Shows
6. New study finds attending Weight Watchers meetings helps reduce the risk for type 2 diabetes
7. Long-term use of anti-anxiety drugs continues in B.C. despite known health risks: UBC study
8. Study finds racial, ethnic disparities in family-centered care for kids with special health needs
9. First study examines postpolypectomy bleeding in colonoscopy patients on uninterrupted clopidogrel
10. Study Challenges Notion That Moderate Drinking Protects the Heart
11. Study: Yogurt-like drink DanActive reduced rate of common infections in daycare children
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... (PRWEB) July 11, 2014 The Capital ... has performed the first procedure in a clinical trial ... inserted in the leg. , During the procedure, done ... Veznedaroglu, an endovascular neurosurgeon, threaded a tiny catheter through ... the body and neck and into the brain. Once ...
(Date:7/10/2014)... acids had healthier joints than those fed diets high ... to Duke Medicine researchers. , The findings, published in ... on July 11, 2014, suggest that unhealthy dietary fats ... osteoarthritis. , "Our results suggest that dietary factors play ... link between obesity and osteoarthritis," said Farshid Guilak, Ph.D., ...
(Date:7/10/2014)... More than 200 experts on aggression, ... street violence, will attend the 21st World Meeting of ... (ISRA) at the Loews Atlanta Hotel, July 15-19. , ... world meeting, which is held every other year on ... together leading scholars from more than 20 different countries, ...
(Date:7/10/2014)... (PRWEB) July 10, 2014 Fatigue, ... for an increasing number of accidents in the ... Safety Reboot. The articles highlight safety issues that ... 317 million accidents occur on the job annually, ... features continue to explore "preventable workplace accidents." , ...
(Date:7/10/2014)... Wisconsin (PRWEB) July 10, 2014 Ticketability.com has ... Tour,” and now Paul McCartney tickets for San Diego are ... in San Diego since 1976, and the newly added September ... California fans. , Click Here to view the ... tickets for Petco Park will become available to the general ...
Breaking Medicine News(10 mins):Health News:New Trial Delivers Chemotherapy to Brain Tumor Through Artery in Leg 2Health News:New Trial Delivers Chemotherapy to Brain Tumor Through Artery in Leg 3Health News:Omega 3 fatty acids lessen severity of osteoarthritis in mice 2Health News:Georgia State Hosts National Conference On Aggression 2Health News:Georgia State Hosts National Conference On Aggression 3Health News:Georgia State Hosts National Conference On Aggression 4Health News:Safety Reboot Magazine Focuses on: Why Extended Hours is Dangerous in the Workplace; Why Custodial Work Can be Dangerous; and Improving Safety for Roofers 2Health News:Safety Reboot Magazine Focuses on: Why Extended Hours is Dangerous in the Workplace; Why Custodial Work Can be Dangerous; and Improving Safety for Roofers 3Health News:Paul McCartney Tickets for San Diego: Ticketability.com Announces Discounted Tickets for McCartney’s Tour Stop at Petco Park on September 28 2
... Every Birth is Safe for Pregnant Women , ... , , ... ... NEW YORK , March 22 ...
... ... ... ... WASHINGTON , March 22 With the passage of the historic health care legislation, the National Medical ...
... has been a major increase in the incidence of ... differing opinions as to why this is (environment, vaccines, ... are still many children who have autistic traits that ... the support they need through educational or health services. ...
... Cycling jerseys and ... ... announced today the addition of a durable, visible and practical backpack for cyclists with ... to help remind motorists to give cyclists at least 3 feet clearance when passing them from ...
... and Services for the Aging, on passage of Health Reform Legislation: , ... , , ... ... "We commend the U.S. ...
... Capital 2010 High Yield Bond and Syndicated Loan Conference in Phoenix, Ariz. , on March 24-26, 2010 . , ... , , ... ... HealthSouth Senior Vice ...
Cached Medicine News:Health News:Amnesty International Urges Congress to Turn Attention to Needed Reforms on Maternal and Childbirth Care 2Health News:Amnesty International Urges Congress to Turn Attention to Needed Reforms on Maternal and Childbirth Care 3Health News:Amnesty International Urges Congress to Turn Attention to Needed Reforms on Maternal and Childbirth Care 4Health News:Amnesty International Urges Congress to Turn Attention to Needed Reforms on Maternal and Childbirth Care 5Health News:National Medical Association, Health System Reform - From Legislation to Implementation 2Health News:National Medical Association, Health System Reform - From Legislation to Implementation 3Health News:New Backpack for Cyclists Sends a Polite Message to Motorists: '3 Feet Please' 2Health News:New Backpack for Cyclists Sends a Polite Message to Motorists: '3 Feet Please' 3Health News:AAHSA Statement on Passage of Health Reform Legislation 2Health News:HealthSouth To Present at Barclays Capital 2010 High Yield Bond and Syndicated Loan Conference 2Health News:HealthSouth To Present at Barclays Capital 2010 High Yield Bond and Syndicated Loan Conference 3
(Date:7/10/2014)... 11. Juli 2014  Dilon Technologies, ... die molekulare Bildgebung, einschließlich molekularer Bildgebung ... CE-Zulassung für sein Navigator ® -Gamma-Sondensystem ... das Produkt jetzt europaweit vertreiben. Dilon ... der europäischen Länder ausgedehnt und bereits ...
(Date:7/10/2014)... , July 10, 2014  The U.S. Department ... three-year grant to University Hospitals (UH) Case Medical Center ... new national model aimed at improving care for patients ... Care," the project will test a unique model developed ... with late-stage disease, significant comorbidities, or demonstrated need for ...
(Date:7/10/2014)... CARLSBAD, Calif. , July 10, 2014 /PRNewswire/ ... products and services, has launched the FreeRunner™ knee ... runners, who suffer from patella mal-tracking return to ... anatomy differently than other braces, providing support when ... move normally when they don,t. Patellofemoral ...
Breaking Medicine Technology:Dilon erhält CE-Zulassung für sein Navigator-Gamma-Sondensystem 2University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 2University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 3University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 4Breg Introduces Knee Brace to Help Runners with Patellofemoral Pain Syndrome 2
... ROCHESTER, N.Y., Sept. 8 VirtualScopics, Inc. (Nasdaq: ... for clinical trials, announced today that Ms. Molly Henderson, ... presenting a corporate overview at the Rodman & Renshaw ... City. Ms. Henderson,s presentation will be on Tuesday, September ...
... N.J., Sept. 8 Today every major pharmaceutical industry ... the future of pharma.  In an unprecedented move, they,re ... the big names in pharma.  All in one place. ... at the Pharma CI Conference & Exhibition at the ...
Cached Medicine Technology:VirtualScopics to Present at the Upcoming Rodman & Renshaw Annual Global Investment Conference 2Pharmaceutical Industry Insiders, VIPs All Coming Together for Future of Pharma Market, Pharmaceutical Competitive Intelligence 2
Part of the GraFix® Cruciate Reconstruction System, which is designed to facilitate arthroscopic anterior cruciate ligament reconstructions....
... Sgarlato Lab's bring a new standard in the ... by Sgarlato Labs. Made of medical grade silicone, ... patient with a high level of flexibility while ... Rods are available in varying stiffnesses. Lengths are ...
... Implant (KGTI) system offers the latest technology ... MPJ. The implant system is anatomically designed ... ,The KGTI is the most advanced reconstructive ... on the market today. The system consists ...
... has been approved for use as an ... seizures in adults and adolescents over 12 ... that are refractory to antiepileptic medications. This ... controlled, clinical trials. Efficacy, measured as median ...
Medicine Products: