Navigation Links
New study confirms link between nonalcoholic steatohepatitis and liver cancer
Date:5/25/2010

A study conducted by researchers at the Cleveland Clinic finds that patients suffering from cirrhosis preceded by nonalcoholic steatohepatitis are at an equal risk of developing hepatocellular carcinoma than those who develop cirrhosis resulting from hepatitis C virus (HCV). Results of this study appear in the June issue of Hepatology, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases (AASLD).

The incidence of hepatocellular carcinoma (HCC) doubled in the United States between 1983 and 2002. It is currently considered the third leading cause of cancer deaths. The increasing incidence of HCC parallels the obesity epidemic. An estimated two-thirds of obese people have some form of fatty liver, including nonalcoholic steatohepatitis (NASH), which can progress to cirrhosis and subsequently HCC. According to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NASH affects 2% to 5% of Americans and ranks as one of the major causes of cirrhosis in the U.S., behind HCV and alcoholic liver disease.

The Cleveland Clinic team, led by Nizar N. Zein, M.D., evaluated a total of 510 patients, 315 with liver cirrhosis secondary to chronic HCV infection and 195 with NASH-induced cirrhosis, to compare the incidence of NASH-cirrhosis to HCV-cirrhosis, and to identify HCC risk factors in each group. Over a median follow-up time of 3.2 years after cirrhosis diagnosis, the yearly cumulative incidence of HCC was 2.6% per year in patients with NASH-cirrhosis compared to 4.0% per year in those with HCV-cirrhosis. These figures suggest that NASH carries a risk of HCC that rivals the risk in patients with HCV-cirrhosis.

Results indicate three factors that are statistically significant in the development of HCC within the NASH-cirrhosis group. An older age at time of cirrhosis diagnosis and a higher BMI were negatively associated with the development of HCC. Among the
'/>"/>

Contact: Dawn Peters
medicalnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Center for the Study of Aging established at University of Denver
2. Heart Drugs Safe for Lungs, Study Finds
3. New national study examines pediatric mobility aid-related injuries
4. Insightful Case Study Details How Electronic Payment Exchange Saved a Global Firm More Than $3 Million in PCI-Related Costs
5. Fat in Males, Females Differs Genetically, Mouse Study Shows
6. New study finds attending Weight Watchers meetings helps reduce the risk for type 2 diabetes
7. Long-term use of anti-anxiety drugs continues in B.C. despite known health risks: UBC study
8. Study finds racial, ethnic disparities in family-centered care for kids with special health needs
9. First study examines postpolypectomy bleeding in colonoscopy patients on uninterrupted clopidogrel
10. Study Challenges Notion That Moderate Drinking Protects the Heart
11. Study: Yogurt-like drink DanActive reduced rate of common infections in daycare children
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/2/2015)... ... 02, 2015 , ... Following the recent report by JAMA Internal Medicine ... merely overweight Americans, Samir Becic emphatically declared a war on obesity in the United ... Becic said. "We must understand the magnitude of this discovery. For that reason, I ...
(Date:7/2/2015)... ... , ... With summer in full swing, Americans are flocking to Canada’s many lakes to reel ... fishing in the world, and it’s easy to understand why. From the Pacific Northwest Coast ... , Recreational fishing is a huge industry, and Americans make up the vast majority of ...
(Date:7/2/2015)... ... July 02, 2015 , ... Get ... the SIGVARIS PERFORMANCE SOCKS. Since the socks were first introduced, they have rapidly ... significant popularity has inspired four new, fun shades including: blue, lime, pink and ...
(Date:7/2/2015)... San Diego, CA (PRWEB) , ... July 02, 2015 , ... ... lifestyle and a passion for social fitness. Built to function as a lifestyle community, ... while giving them the opportunity to network, meet, and participate in discussions or group ...
(Date:7/2/2015)... Pennsylvania (PRWEB) , ... July ... ... largest e-commerce janitorial supply company , announced today that it has ... Products. The acquisition will make CleanItSupply.com the largest distributor of Rubbermaid Commercial ...
Breaking Medicine News(10 mins):Health News:Samir Becic's Health Fitness Revolution Declares War Against Obesity in America 2Health News:Samir Becic's Health Fitness Revolution Declares War Against Obesity in America 3Health News:Samir Becic's Health Fitness Revolution Declares War Against Obesity in America 4Health News:SIGVARIS is Sporting Four Brand New Colors in the Popular PERFORMANCE SOCK Product Line 2Health News:ActiveBunch.com Launches as a Social Community for People with Active Lifestyles 2Health News:CleanItSupply.com Acquires eRubbermaid.com 2
... suntan is mostly associated with good health and vitality. However, ... body to manufacture vitamin D. //It doesn't take much sunlight ... certainly far less than it takes to get a suntan. ... complex motivations involved with UV light (UVL) tanning behavior. For ...
... Romond reported from two separate trials that Breast ... Herceptin therapy using trastuzumab. //The results of their ... England Journal of Medicine. The researchers compiled results ... only chemotherapy with patients receiving both chemotherapy and ...
... from Kyoto University have found that daily gargling with povidione-iodine ... the study have been published in the American Journal of ... healthy volunteers between the age group of 18 to 65. ... the first group gargled water with povidone-iodine, the second group ...
... There is an insufficient supply of deceased donor kidneys ... of living donor kidney transplants.// ,A recent ... focuses on the insufficient supply of transplantable kidneys, strategies ... living donor renal transplants, and the results of the ...
... loss of sexual interest have often been associated with ... men who are long-term alcohol users,// with the prevalence ... cause gonadal disorders, including structural testicular changes and a ... might be involved in the hypogonadism and feminization phenotype. ...
... of insults, such as surgery, infection and injury by ... of the immune system, creating a number of potent ... for fighting infection, may damage the host. Its strength ... mediators being the key mediators. ,Recently, Robert ...
Cached Medicine News:Health News:Trastuzumab therapy effective for Breast cancer patients with Her-2/neu positive 2Health News:Daily Gargling May Prevent Common Colds 2Health News:Strategies To Boost Living Donor Kidney Transplants 2Health News:Detrimental Effect Of Chronic Alcoholism On Male Fertility 2Health News:The ideal composition of intravenous lipid emulsion 2
(Date:7/2/2015)... July 2, 2015  New product launches are critical ... role in educating thought leaders about new products, Medical ... influence how well a new therapy performs at launch. ... research and consulting leader Best Practices, LLC, critical aspects ... focus on are early stage thought leader (TL) interaction, ...
(Date:7/2/2015)... , July 2, 2015 Roche,s ... conspicuously high-growth market segment in hematology testing, according ... said that Roche,s recent unveiling of its Bloodhound digital ... cobas m 511 hematology analyzer – ... capture growth enjoyed by current leader CellaVision, but ...
(Date:7/2/2015)... LAKEWAY, Texas , July 2, 2015   ... on being the leading provider for non-invasive aesthetics in ... offer state-of-the-art tattoo removal treatments with the Astanza Duality ... transform their well being through various medical and laser ... patients with unwanted ink a clear solution to their ...
Breaking Medicine Technology:Medical Affairs Role in Thought Leader Education is Key Success Factor for New Product Launches in the Pharmaceutical Industry 2Kalorama: With Bloodhound, Roche Closes in on High-Growth Hematology Segment 2Kalorama: With Bloodhound, Roche Closes in on High-Growth Hematology Segment 3EVO Offers Advanced Laser Tattoo Removal With Astanza Duality In Lakeway, TX 2
... ... ... ... ...
... , ... ... ... ...
Cached Medicine Technology:Diabetics Twice as Likely to Have Hearing Loss; North Carolina HearUSA Centers to Offer Free Hearing Screening and Diabetes Video in March 2Diabetics Twice as Likely to Have Hearing Loss; North Carolina HearUSA Centers to Offer Free Hearing Screening and Diabetes Video in March 3Diabetics Twice as Likely to Have Hearing Loss; North Carolina HearUSA Centers to Offer Free Hearing Screening and Diabetes Video in March 4Diabetics Twice as Likely to Have Hearing Loss; North Carolina HearUSA Centers to Offer Free Hearing Screening and Diabetes Video in March 5Diabetics Twice as Likely to Have Hearing Loss; North Carolina HearUSA Centers to Offer Free Hearing Screening and Diabetes Video in March 6Diabetics Twice as Likely to Have Hearing Loss; North Carolina HearUSA Centers to Offer Free Hearing Screening and Diabetes Video in March 7Diabetics Twice as Likely to Have Hearing Loss; Missouri HearUSA Centers to Offer Free Hearing Screening and Diabetes Video in March 2Diabetics Twice as Likely to Have Hearing Loss; Missouri HearUSA Centers to Offer Free Hearing Screening and Diabetes Video in March 3Diabetics Twice as Likely to Have Hearing Loss; Missouri HearUSA Centers to Offer Free Hearing Screening and Diabetes Video in March 4
... With the OPMI VISU 210, Carl Zeiss ... be described as absolute state-of-the-art for ophthalmic surgery. ... placed on it by surgeons and it offers ... and contrast. With its completely integrated assistant's microscope ...
Blood grouping tubes are available in two formulations, ACD-A, ACD-B or with a CPDA solution. Blood grouping tubes are for blood grouping determinations and also for cell preservation....
MONOJECT Brown Stopper...
BD Vacutainer® PST™ Tubes contain spray-coated lithium heparin and a gel for plasma separation. They are used for plasma determinations in chemistry....
Medicine Products: