Navigation Links
New study aims to improve long-term treatment for patients with bipolar disorder
Date:5/24/2011

NEW YORK (May 23, 2011) -- Patients with bipolar disorder may be eligible for a new clinical research study comparing two medications -- quetiapine (Seroquel), a widely prescribed second-generation antipsychotic mood-stabilizing medication, and lithium, the gold-standard mood stabilizer.

NewYork-Presbyterian Hospital/Weill Cornell Medical Center is one of 10 sites nationally -- and the only site in the greater New York metropolitan area -- participating in the CHOICE (Clinical Health Outcomes Initiative in Comparative Effectiveness) study. The research is funded by a $10 million grant from the U.S. Agency for Healthcare Research Quality (AHRQ).

"Antipsychotic drugs have long been known to be useful for the treatment of bipolar disorder, but neurological side effects and toxicity have limited their long-term use. The good news is that the newer-generation antipsychotic drugs like quetiapine appear to be effective while having fewer neurological side effects," says Dr. James H. Kocsis, site principal investigator, director of the Payne Whitney Affective Disorders Research Clinic at NewYork-Presbyterian Hospital/Weill Cornell Medical Center and professor of psychiatry at Weill Cornell Medical College. "In this context, it is important that we compare the relative utility of the old-fashioned mood stabilizers like lithium and the newer second-generation antipsychotic drugs -- with the ultimate goal of improving long-term treatment for patients with bipolar disorder."

Researchers will follow 480 patients with bipolar disorder randomized to one of the two medications over a six-month period. Participants can continue taking other prescriptions, such as antidepressants, as long as they are not antipsychotic drugs. Often patients with bipolar disorder need three medications to feel well, explains Dr. Kocsis.

Bipolar disorder is a lifelong, chronic and highly recurrent mood disorder characterized by episodes of mania that alternate with episodes of major depression. Symptoms can negatively affect personal relationships, job or school performance, and may result in suicide.

The study is coordinated through the Massachusetts General Hospital (MGH) Bipolar Clinic and Research Program. The lead principal investigator is Dr. Andrew A. Nierenberg, director of the MGH Bipolar Research Program.

The AHRQ grant is part of an investment made under the American Recovery and Reinvestment Act of 2009, which designated $1.1 billion to support patient-centered outcomes research. This research is designed to inform health care decisions by providing evidence and information on the effectiveness, benefits and harms of different treatment options.


'/>"/>

Contact: Takla Boujaoude
tab2016@med.cornell.edu
212-821-0560
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College
Source:Eurekalert

Related medicine news :

1. Medicare improved Canadian doctors salaries: Queens University study
2. IUPUI study first to look at early treatment of depression to reduce heart disease risk
3. A Cultured Man Is a Healthier, Happier Man: Study
4. New study finds that violence doesnt add to childrens enjoyment of TV shows, movies
5. UTMB researcher receives $3 million NIH grant to study aging in Mexico
6. Study finds patient navigation increases colorectal cancer screening in ethnically diverse patients
7. Study links acetaminophen to lower prostate cancer risk
8. Some Dentists Reluctant to Treat Kids on Medicaid: Study
9. Younger Docs More Likely to Prescribe Drugs for Heart Disease: Study
10. Common test could help predict early death in diabetes, study shows
11. Study identifies novel role for a protein that could lead to new treatments for rheumatoid arthritis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/23/2017)... ... 2017 , ... Current Meditation , a new meditation ... the U.S. starting this spring. Current Meditation focuses on “meditation for the modern ... Meditation will be the first meditation concept in the U.S. offering franchising opportunities, ...
(Date:2/23/2017)... ... February 23, 2017 , ... The ... the Rhode Island Consortium for Autism Research and Treatment (RI-CART) and Cinemaworld to ... autism spectrum disorder (ASD) to see films in an environment that accommodates their ...
(Date:2/23/2017)... ... 23, 2017 , ... CALNOC, the nation’s first and only nursing quality indicators ... – Empowerment, Value and Collaboration – in Seattle, WA on October 23, 2017. , ... Health System in Seattle since 2000. In addition to his role at Virginia Mason, ...
(Date:2/23/2017)... ... February 23, 2017 , ... Curemark, LLC announced today that the Blüm Study, ... children aged 3-8 with Autism, is now enrolling at three new sites. These new ... United States. , “There are currently no approved drugs that address the core ...
(Date:2/23/2017)... ... 2017 , ... Thomas Vas-Don suffered from severe injury due to ... able to successfully recover. In “ Origin & Insertion Charts for Massage Therapists ” ... principals of massage, anatomy , trigger points and referral pain patterns . ...
Breaking Medicine News(10 mins):
(Date:2/23/2017)... , February 23, 2017 On Wednesday, ... day as four out of nine sectors finished the trading ... managed a flat closing. Major US indices were also mixed ... the day at 5,860.63, slightly down by 0.09%; the Dow ... and the S&P 500 closed at 2,362.82, down 0.11%. This ...
(Date:2/23/2017)... , February 23, 2017 ML Capital ... in Colorado Highlife Tours , a ... plan in partnership with Puration, Inc. (USOTC: PURA) to enter ... cannabis tours product. The Colorado Highlife Tours acquisition announced today is ... tourism strategy. ...
(Date:2/23/2017)... VANCOUVER, British Columbia , Feb. 23, 2017 ... today announced its year end 2016 financial results.  ... 2017, OncoGenex, and Achieve Life Science, Inc., a privately held ... a definitive merger agreement under which OncoGenex will acquire ... proposed merger, Achieve,s stockholders are expected to own 75% ...
Breaking Medicine Technology: