Navigation Links
New study: Incidence and mortality of PCa after termination of PSA-based screening

Milan, 15 March 2013 - Men who participate in biennial PSA based screening have a lower risk of being diagnosed as well as dying from prostate cancer up to 9 years after their last PSA test, according to the results of a new study to be presented at the 28th Annual EAU Congress in Milan

A joint Swedish-UK study aimed to examined the risk of developing prostate cancer after last invitation to screening. This investigation follows up on previous publication from the Gteborg randomized screening trial (part of ERSPC) by the same group which showed that biennial PSA screening lowered PC mortality with 44%

In the course of the study, which launched in 1995, 20000 men were randomized and 9 952 have been invited every second year for PSA testing while 9952 were randomized to a control arm. All cases of prostate cancer in the screening (n= 6449) as well as the control arm (n= 6974) after reaching the upper age limit for invitation (median 69 range 67-71 years) were identified by matching with the Regional Cancer Register in western Sweden.

For all deaths in men with prostate cancer, a review of cause of death was performed by an independent committee, the date of follow-up being 30 June 2012 or at a maximum of 12 years. PCs diagnosed were classified into low, intermediate or high/advanced risk groups and all attendees were defined as participating at least once

In the course of the study, a total of 173 men with were diagnosed with prostate cancer in the invited arm (with a median follow-up of 4.8 years) and 371 were diagnosed in the control arm (with a median follow-up of 4.9 years).

Up to 9 years after last invitation all risk groups were more commonly diagnosed in the control arm but after 9 years the rates in the screening arm caught up, other than those for the low risk group. In the invited arm, non-attendees had an incidence similar to that of the control arm. Also mortality in PC was lower in the screening arm up to 9 years, which is approximately 50 % of that in the control arm, after termination of screening. At the same time, in the interval of 9-12 years, the screening group had a similar mortality rate to the control.


Contact: Ivanka Moerkerken
European Association of Urology

Related medicine news :

1. Study: Smoking Increases HPV Risks; polyDNA Recommends Gene-Eden-VIR Against HPV
2. Omega XL Reports New Independent Study: Omega-3s Can Boost Children’s IQ
3. Study: 15% of Children Ages 10 - 14 Consider Using Steroids; polyDNA Recommends Muxscle for Safe Muscle Building
4. Study: Dynamic new software improves care of aging brain
5. Bel Marra Health Reports on a New Study: Female Obesity Could Be Due to Less Participation in Household Tasks
6. Study: Steroid Abuse in Teens is Increasing; polyDNA Recommends Muxscle for Safe Muscle Building
7. Study: Catheter-based varicose vein treatments more cost-effective
8. Penn study: Financial incentives affect prostate cancer treatment patterns
9. Study: Mega Vitamins Wont Help After Heart Attack, Chelation Treatment Might
10. Study: Diabetic medication may protect patients from developing heart failure
11. Doctors Health Press Reports on German Study: Only 20% of Patients Get Colonoscopies, Important in Preventing and Diagnosing Colon Cancer
Post Your Comments:
(Date:10/13/2015)... ... October 13, 2015 , ... Bambeco, Inc., the ... décor, today announced it closed on a $20.5 million funding round led by ... to support the Company’s continued rapid growth and expansion, broaden the Company’s product ...
(Date:10/13/2015)... san diego, ca (PRWEB) , ... October 13, 2015 , ... ... plumbing company in San Diego, also offering expert reconstruction and flood remediation services. ... caliber of employees. They have been named the Best San Diego plumber two years ...
(Date:10/12/2015)... ... October 13, 2015 , ... Career Step, an online ... of its new Professional Medical Coding and Billing with Applied PCS career training ... ICD-10-PCS code sets, earn the Certified Professional Coder (CPC) and Certified Coding Associate ...
(Date:10/12/2015)... ... October 12, 2015 , ... Amerec , a ... of spa and skin care equipment, will be displaying custom sauna and steam room ... With many high-end resorts and spas as customers, SpaEquip is recognized for their ability ...
(Date:10/12/2015)... ... October 12, 2015 , ... The Horizon Foundation for New Jersey has ... public health and enhancing the quality of life in the Garden State. The grants, ... non-profit organizations. , The charitable arm of Horizon Blue Cross Blue Shield of ...
Breaking Medicine News(10 mins):
(Date:10/12/2015)... COSTA MESA, Calif. , Oct. 12, 2015 ... reaffirmed the accreditation of Harbor Compounding Pharmacy in ... accreditation is awarded in recognition of the pharmacy,s ... --> ... --> ...
(Date:10/12/2015)... Calif. , Oct. 12, 2015 /PRNewswire/ ... and Chief Scientific Officer of Asterias Biotherapeutics, ... company in the emerging field of regenerative ... webcast, sponsored in part by Asterias Biotherapeutics, ... Lebkowski will discuss the progress to date ...
(Date:10/12/2015)... , Oct. 12, 2015  In a Sutter ... the Journal of Neurology, Neurosurgery, and Psychiatry, the blood ... brain atrophy and cognitive decline in patients in the ... --> --> IVIG, extracted from the ... to amyloid, an abnormal brain protein found in patients ...
Breaking Medicine Technology: