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New studies highlight obesity's impact on gastrointestinal health
Date:10/18/2010

17.5 months, according to the study.

"These findings support previous data that there may be an association with non-cirrhotic HCC and an elevated BMI as well as diabetes independent of steatosis," said Dr. Mitlyng.

Body Mass Index was also linked with adenoma recurrence in the short and long-term, in another study unveiled today, "The Association of Obesity with Short and Long-Term Risk of Adenoma Recurrence: Analysis of the Polyp Prevention Trial and Continued Follow-Up Study."

"Previous prospective studies have evaluated the association between obesity and colorectal adenoma recurrence within four years of follow-up, a relatively short duration," said Adeyinka Laiyemo, M.D. "We aimed to examine long-term cumulative risk of adenoma recurrence in association with obesity among participants in the Polyp Prevention Trial (PPT), a multicenter, randomized controlled trial that evaluated the effect of a low fat, high fiber, fruits and vegetable diet on the risk of colorectal adenoma recurrence," explained Dr. Laiyemo.

The study, found that at baseline, approximately 50 percent of the 760 participants were overweight (BMI 25‐29 kg/m2) and 25 percent were obese (BMI = 30 kg/m2). The mean age of participants was 59.7 years and 66 percent were males. The mean total duration of follow-up was 8.4 years (range 4.9 ‐12.4 years).

"When compared with participants with normal BMI, overweight and obese participants have an elevated risk of adenoma recurrence during both short and term and long-term," said Dr. Laiyemo. "Since BMI was positively associated with adenoma recurrence in short and long-term, lifestyle modification should be encouraged."

High Prevalence of Coronary Artery Disease in Patients with Non-Alcoholic Fatty Liver Disease

With Non-Alcoholic Fatty Liver Disease (NAFLD) affecting up to 20 percent of adults and nearly five percent of children, researchers aimed to assess the prevalence and predictors of coronary ar
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Contact: Jacqueline Gaulin
jgaulin@acg.gi.org
202-255-5541
American College of Gastroenterology
Source:Eurekalert

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