Navigation Links
New studies add insights to infant feeding and obesity issue

SAN DIEGO (April 9, 2008) On Wednesday, April 9, 2008, a symposium at the American Society for Nutritions annual meeting at Experimental Biology was held in which noted scientists discussed new infant feeding studies that used methodology such as randomized clinical trials (involving breastfeeding promotion) as well as sibling pairs analysis. These studies may offer new insights into possible associations between infant feeding and health outcomes such as obesity.

The symposium, Infant Feeding and the Development of Obesity: What Does the Science Tell Us", sponsored by the International Formula Council (IFC)* and chaired by Linda Adair, Ph.D., professor of nutrition at the University of North Carolina at Chapel Hill, brought together international experts in the field of infant nutrition to present their recent findings.

Featured researchers included David Barker, M.D., Ph.D., professor of clinical epidemiology at the University of Southampton, UK and professor of Cardiovascular in the Department of Medicine at the Oregon Health and Science University, whose soon-to-be published study examines breastfeeding in a large group of sibling pairs that were followed into their late 60s.

This type of study design controls for maternal factors, according to Dr. Barker. Differences in the long-term effects of breast and bottle feeding may reflect differences in the mothers rather than the effects of feeding itself. Maternal factors include maternal health status, maternal care-giving, motherchild interactions or other health-related behaviors of the mother that may interfere with determining the association of infant feeding and health outcomes and the strength of any possible associations.

Other study designs such as the randomized clinical trial on breastfeeding and health outcomes in infants in Belarus recently conducted by Michael Kramer, M.D., a pediatrician and perinatal epidemiologist at McGill University in Montreal, provide evidence that research design can have a significant impact on infant feeding study results. In a randomized infant feeding clinical trial, known as the gold standard in research, infants would be randomly assigned to be breastfed or formula-fed; however, such trials are generally not feasible in infant feeding research, since most mothers determine their infants feeding method. Dr. Kramer randomly assigned hospitals to implement breastfeeding promotion practices and standard care. He found that despite the substantial increase in prolonged and exclusive breastfeeding among mothers receiving the intervention, there were no differences between their children (n= 7,108 subjects) and the children of mothers from the control hospitals (n= 6,781 subjects), that did not implement breastfeeding promotion practices, on several measures of adiposity at 6.5 years of age.

These findings challenge the concept that breastfeeding reduces the risk of obesity in childhood, as some other studies have found. Speaking of the strength of his study design and the fact that other studies due to their design may have been prone to inherent bias, Dr. Kramer noted, Previously reported beneficial effects on these outcomes (measurements of obesity) may be the result of uncontrolled confounding and selection bias. The study performed by Dr. Kramer represents the largest randomized trial done to date in the area of human lactation.

Other researchers at the symposium presented the outcomes of more traditional epidemiologic studies that were based on observational designs and thus had limitations such as not being able to control subjects behavior. Beth Mayer-Davis, Ph.D., R.D., professor of nutrition and diabetes researcher at University of North Carolina at Chapel Hill, discussed findings from her research on infant feeding and diabetes in ethnic groups in a United States population. In her observational study of less than 300 subjects, mothers of children with diabetes were asked to recall if and for how long they breastfed their infant. Dr. Mayer-Davis reported that breastfeeding appeared to reduce the risk for development of type 2 diabetes in youth, possibly mediated in part by weight status in childhood.

Nancy Butte, Ph.D., professor of pediatrics at the Childrens Nutrition Research Center at Baylor College of Medicine, discussed early infant feeding practices and effects on obesity. Dr. Butte presented her work from the VIVA LA FAMILIA study, an observational study with a cohort of 1,030 Hispanic children. Dr. Butte noted that although breastfeeding appeared to have a small protective effect against childhood obesity, other genetic and environmental factors far supersede infant feeding practices as risk factors for childhood obesity.


Contact: Marisa Salcines
Kellen Communications

Related medicine news :

1. Gene Studies of Male-Female Differences Often Flawed
2. Two studies published in the Lancet
3. Study of Studies Finds No Risk to Children From Phthalates in Toys
4. Just Completed Studies Reveal Impact of New Medicare Reimbursement Regulations
5. Studies Prove Exercise Can Heal the Body Mind and Soul
6. Studies Shed New Light on Breast Cancer, Treatment
7. Multi-Year Compendium of Pharmaceutical Case Studies Available from Best Practices, LLC
8. Genomic Health Announces Multiple Studies on Oncotype DX(TM) Presented at 2007 American Society of Clinical Oncology (ASCO) Breast Cancer Symposium
9. Best Practice Database: Complimentary Excerpt of Three Sales Force Excellence Studies
10. Major Pharma Clinical Case Studies From Amgen, AstraZeneca, GSK, Intermune, Cephalon Inc, Sunesis Pharmaceuticals and Dartmouth Medical School During Fall Clinical Focused Programs
11. NIH awards Einstein multimillion dollar grant to extend studies of exceptional longevity
Post Your Comments:
(Date:11/30/2015)... ... ... While powdered supplements and drinks can reduce food preparation time, locating the ... has found an easy to keep track of the scoop. , He developed a ... a canister or other container handy and readily accessible. As such, it prevents the ...
(Date:11/30/2015)... ... November 30, 2015 , ... ... announced at the Radiology Society of North America (RSNA) annual meeting, being held ... 60% growth from 2014. Throughout 2015, the company has completed installations for ...
(Date:11/30/2015)... ... November 30, 2015 , ... Volpara Solutions ... density assessment and enterprise analytics solutions, here at the 101st Annual Radiological ... booth #2377). Volpara’s quantitative breast imaging tools enable personalized measurements of volumetric ...
(Date:11/30/2015)... ... ... It’s inevitable that everyone will experience death in his or her lifetime. Whether ... among us. It is your perspective, however, that determines how you view death in ... Sky understands that she may see death more frequently than most. As she was ...
(Date:11/30/2015)... ... November 30, 2015 , ... ... the speakers for “Value-Based Payer-Provider Partnerships: Three Case Studies,” an upcoming Dec. ... care arrangements: Essentia Health and UCare, MissionPoint Health Partners, and Intel Corp. ...
Breaking Medicine News(10 mins):
(Date:11/30/2015)... Sectra (STO: SECT B) ... into a multi-year agreement to provide Breast Imaging PACS ... Breast Care to increase collaboration with sub-specialists around the ... --> Sectra (STO: SECT B) ... into a multi-year agreement to provide Breast Imaging PACS ...
(Date:11/29/2015)... and NUREMBERG, Germany , ... meeting, innovation leader Ziehm Imaging invites attendees to experience ... on the market. The highlight on display is Ziehm ... flat-panel technology that provides a 16 cm edge length ... Vision RFD Hybrid Edition, the first fully motorized mobile ...
(Date:11/29/2015)... CHICAGO , Nov. 29, 2015   National ... expansion of its client base, including notable statewide ... the company,s flagship solution, ACR Select, more than ... EHR order entry workflow. ACR Select provides real-time ... a patient,s condition and has been implemented at ...
Breaking Medicine Technology: