Navigation Links
New strategy likely to speed drug development for rare cancers
Date:9/15/2011

D ependymoma cells, four demonstrated a two-fold greater ability to block the growth of the tumor cells, but not normal cells. The drugs included 5-FU and two closely related compounds. The fourth was beta-escin, which belongs to a family of drugs that are generating interest as potential chemotherapy agents.

5-FU also proved more effective than four other chemotherapy drugs in slowing tumor growth and extending the lives of mice with subtype D ependymoma. 5-FU also appeared less toxic to normal mouse brain cells than another drug, bortezomib, included in the study. The findings provided preliminary evidence that the screening system might provide an early indication of drug toxicity. The information could help guide treatment and prioritize drugs for development, researchers said.

The screening also highlighted a possible role for kinase inhibitors. Those are drugs that block activity of proteins that help drive cell division and sustain tumors. More than 18 inhibitors are in clinical trials that target the kinases this study tied to proliferation of both normal and ependymoma tumor cells.


'/>"/>

Contact: Summer Freeman
summer.freeman@stjude.org
901-595-3061
St. Jude Children's Research Hospital
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Study points to strategy for overcoming resistance to targeted cancer drug
2. Research identifies marketing mix strategy for pharmaceutical firms
3. New Strategy Trains All Soldiers in Trauma Care
4. NIH supports new research strategy for finding a cure for HIV
5. Coping Strategy Depends on Strength of Emotion: Study
6. Innovative duct tape strategy saves hospitals time, money; improves infection prevention
7. New strategy to attack tumor-feeding blood vessels
8. Researchers develop strategy to improve patient adherence
9. Potential new strategy to reduce catheter blockage
10. A Pacman strategy to boost the immune system to fight cancer
11. Scientists devise targeted therapy strategy for rare form of childhood cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... VogueQueen is a seasoned and trusted leader who ... are thrilled to have it lead the wedding dress industry ... of prom dresses for the global market. , “The CEO ... and he focuses on continuing the goal of operational excellence ...
(Date:1/22/2015)... (PRWEB) January 23, 2015 Angelweddingdress is a ... business invites its customers to follow it on Facebook, Twitter, ... a Valentine’s Day gift. Angelweddingdress draws a lottery every week. ... Sale to Feb. 28, 2015. Click Angelweddingdress homepage ...
(Date:1/22/2015)... AngelWeddingDress, the premier women’s dress supplier, has recently released ... website of AngelWeddingDress.com to find more details. , ... for a bridal party. AngelWeddingDress offers a variety of ... maternity wedding dresses are specially designed for 2015. , ...
(Date:1/22/2015)... 2015 Juvent Sports ( http://www.juventsports.com ) ... PGA Merchandise Show to bestow a Juvent Sports Achievement ... golfer, Arlene McKitrick. The award commemorated and congratulated McKitrick ... win. She won her first amateur tournament in 1979 ...
(Date:1/22/2015)... New York (PRWEB) January 22, 2015 ... after Fresenius Medical Care recalled its GranuFlo and NaturaLyte ... multidistrict litigation underway in U.S. District Court, District of ... dated January 20th, the Court has remanded a case ...
Breaking Medicine News(10 mins):Health News:VogueQueen Unveils New Designs of Prom Dresses for 2015 2Health News:Angelweddingdress Invites Its Customers To Follow It On Facebook, Twitter, And Pinterest 2Health News:AngelWeddingDress Has Recently Released Its Collection Of 2015 Maternity Wedding Dresses 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 3Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 3Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 4
... More and more cancer patients are,looking for ... quality of,life during difficult treatment regimens., ... ) at:, http://media.medialink.com/WebNR.aspx?story=35774 ) Philips Research is ... increase the effectiveness and reduce the side,effects of ...
... by Charge for Goodwill Impairment, SALT LAKE CITY, ... announced results for its fourth quarter,and fiscal 2008 year-end ... concluded in the fourth,quarter of fiscal year 2007 and ... significant revenue increases for the fourth quarter and,full fiscal ...
... G. Komen For the Cure(R), MINNEAPOLIS, Sept. 29 ... second largest company-owned gourmet coffeehouse,operator based in the U.S., ... roastmasters with Amy,s Blend coffee. Now available for a ... to breast cancer,in 1995 at the age of 33., ...
... Women Do Not Feel Knowledgeable About Their,Cancer Risks and ... Educate and Entertain, LOS ANGELES, Sept. 29 ... Johnson and Nastia Liukin, along with Team USA,will join ... a national network,television special, Frosted Pink with a Twist, ...
... Care Knowledge Releases Results of First ... ... WellPoint Institute of Health,Care Knowledge today released its first study: "Choosing ... research studies, fact sheets and policy statements designed,to help create more ...
... Gary Bell named President of Jackson Hospital Affiliates , ... ... -- www.jacksonhealthcare.com [Jackson Healthcare] (JH), an Atlanta based healthcare staffing ... The purpose of the Jackson Hospital Affiliates is to acquire ...
Cached Medicine News:Health News:Dynatronics Announces Fiscal Year 2008 Operating Results 2Health News:Dynatronics Announces Fiscal Year 2008 Operating Results 3Health News:Dynatronics Announces Fiscal Year 2008 Operating Results 4Health News:Dynatronics Announces Fiscal Year 2008 Operating Results 5Health News:Caribou Coffee Honors Memory of One of Its Own With Amy's Blend 2Health News:Video: 2008 US Olympic Gymnastic Superstars Join Today's Top Music Icons for Women's Cancer Awareness Network Special, Frosted Pink with a Twist 2Health News:Video: 2008 US Olympic Gymnastic Superstars Join Today's Top Music Icons for Women's Cancer Awareness Network Special, Frosted Pink with a Twist 3Health News:Video: 2008 US Olympic Gymnastic Superstars Join Today's Top Music Icons for Women's Cancer Awareness Network Special, Frosted Pink with a Twist 4Health News:Access to Physicians Is Consumers' Highest Priority When Choosing a Health Plan, According to New Study 2Health News:Access to Physicians Is Consumers' Highest Priority When Choosing a Health Plan, According to New Study 3Health News:Jackson Healthcare Forms New Operating Company to Acquire and Manage Hospitals 2
(Date:1/22/2015)... 2015  ViewRay™, a privately held medical device company, announced ... agreement with ITOCHU Corporation (Tokyo Stock Exchange TYO: 8001) ... treatment of cancer in Japan . ... first and only MRI-guided radiation therapy system that images ...
(Date:1/22/2015)... RMD ) today announced results for its quarter ... million, a 10 percent increase compared to the quarter ended ... currency basis). Net income was $91.2 million, an increase of ... Diluted earnings per share for the quarter were $0.64, an ...
(Date:1/22/2015)... Jan. 22, 2015  Bio-Techne Corporation (NASDAQ: TECH ... first member of the new Simple Plex platform through ... launch represents the re-branding of the previously acquired CyPlex ... platform is a transformative immunoassay technology which integrates an ...
Breaking Medicine Technology:ITOCHU Named the Exclusive Distributor for ViewRay's MRI-Guided Radiation Therapy System in Japan 2ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 2ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 3ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 4ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 5ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 6ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 7ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 8ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 9ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 10ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 11Bio-Techne Launches Simple Plex Platform 2Bio-Techne Launches Simple Plex Platform 3
... Unilife Corporation ("Unilife" or "Company") (Nasdaq: UNIS ; ... quarter and fiscal year ended June 30, 2010. ... 2010 has been a pivotal year for Unilife, as we ... to the U.S. and our listing on NASDAQ." ...
... Wash., Aug. 30 SCOLR Pharma, Inc. (NYSE AMEX: ... agreement with The Emerson Group to provide sales support for ... products. The Emerson Group ( www.emersongroup.com ), ... that provides strategic consulting and sales execution services to companies ...
Cached Medicine Technology:Unilife Corporation Announces Preliminary Financial Results for Fourth Quarter and Fiscal Year 2010 2Unilife Corporation Announces Preliminary Financial Results for Fourth Quarter and Fiscal Year 2010 3Unilife Corporation Announces Preliminary Financial Results for Fourth Quarter and Fiscal Year 2010 4Unilife Corporation Announces Preliminary Financial Results for Fourth Quarter and Fiscal Year 2010 5Unilife Corporation Announces Preliminary Financial Results for Fourth Quarter and Fiscal Year 2010 6Unilife Corporation Announces Preliminary Financial Results for Fourth Quarter and Fiscal Year 2010 7Unilife Corporation Announces Preliminary Financial Results for Fourth Quarter and Fiscal Year 2010 8SCOLR Pharma, Inc. Signs Agreement with The Emerson Group to Provide Sales Support for Nutritional & OTC Products 2SCOLR Pharma, Inc. Signs Agreement with The Emerson Group to Provide Sales Support for Nutritional & OTC Products 3
This table has an adjustable height, two legs, and square post. Clamps and standard 1" (2.5 cm) pad included....
... orthopedic procedures. Molded armrests expand ... for the surgeon's comfort. Built-in ... any O.R. table. Split leg ... stability. Optional post or tee ...
The DHS Basic Set is available with either self-tapping or non-self-tapping screws. Either instrument set provides complete instrumentation in one graphic case for use with the Universal Implant Set,...
When You Need Optimal Patient Comfort with Minimal Weight at a Nonunion Site...Demand The OrthoPak Noninvasive Bone Growth Stimulator. , ,Most Appropriate for the Proximal Femur, Metatarsal/Tar...
Medicine Products: