Navigation Links
New statistical method offers automatic mitotic cell detection for cancer diagnosis
Date:11/12/2012

Scientists have developed a statistical image analysis method which can assist in the grading of breast cancer by automatically segmenting tumour regions and detecting dividing cells in tissue samples.

The system, developed at the University of Warwick, promises to bring objectivity and automation to the cancer grading process which is used to determine the aggressiveness of the treatment offered to the patient.

Number of mitotic cells, cells which are dividing to create new cells, is a key indicator used by histopathologists for diagnosing and grading cancer.

At present the dominant system in the UK and much of the world the Nottingham Grading System - is based on expert analysis of tissue samples to determine the severity of the cancer.

As a subjective system dependent on visual analysis, it can produce substantial variability in diagnostic assessment, resulting in low agreement between pathologists.

A pilot study conducted by researchers at Warwick found there to be an agreement of 19 per cent between three pathologists in identifying the mitotic cells.

In response to the need for more objectivity, a team at the University of Warwick have developed a three-step method which takes an image of tissue samples and applies statistical modelling to detect mitotic cells in that image.

Dr Nasir Rajpoot from the Department of Computer Science at the University of Warwick said: "It has long been recognised that there is a need to increase objectivity in the cancer grading process.

"This grading process determines the treatment offered to people who have been diagnosed with cancer, so it's vital to get it right in order to prevent patients undergoing unnecessarily aggressive treatments.

"We believe our method takes a significant step towards this by offering an objective, automatic technique to assist the pathologists in grading of breast cancer."

The method consists of three key steps. Firstly it segments the tumour margins, a
'/>"/>

Contact: Anna Blackaby
44-024-765-75910
University of Warwick
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Nonsurgical Method to Measure Brain Pressure Shows Promise
2. New Method to Reveal Alzheimers Marker Shows Promise
3. New method to measure work addiction
4. Advanced genetic screening method may speed vaccine development
5. OHSU Oregon National Primate Research Center develops new, safer method for making vaccines
6. Hear to see: New method for the treatment of visual field defects
7. Safer Grilling Methods Might Cut Cancer Risk
8. Quick-Reversal Method May Be at Hand for New Blood Thinner
9. New delivery method improves efficacy of 2 common Parkinsons disease medications
10. Electronic data methods research seeks to build a learning health care system
11. New Stanford method enables sequencing of fetal genomes using only maternal blood sample
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2014)... “Copay coupons,” a drug manufacturer marketing ... among patients with prescription drug coverage, may now be ... report from the Department of Health and Human ... laws prohibit suppliers from offering side-payments to increase sales ... , The report highlights that two recent surveys, including ...
(Date:9/19/2014)... Unbound , an international humanitarian organization based ... the Philippines being affected by both a tropical storm and ... to the nearest public schools while others moved to higher ... winds to portions of the northern Philippines. , The ... with more than 10 feet of water. , “It ...
(Date:9/19/2014)... FRIDAY, Sept. 19, 2014 (HealthDay News) -- As kids ... the targets of cyberbullies, according to a recent study. ... grades 5 through 8 found that verbal and physical ... patterns vary, bullying intervention and prevention strategies must address ... bullying among boys and girls, the researchers said. The ...
(Date:9/19/2014)... of human cancers have abnormally upregulated chemical signals ... are controlled during tumor formation is not fully ... Fayngerts, PhD, both researchers in the department of ... of Medicine, University of Pennsylvania, and colleagues report ... cancer by targeting these pathways. , Lipid second ...
(Date:9/19/2014)... (Lebanon, NH 9/18/14) A leading Dartmouth researcher, working with ... co-authored a paper published today in the Journal ... telomeres increase the risk of melanoma. , "For the ... the length of these telomeres play a part in ... the study Mark Iles, PhD, School of Medicine at ...
Breaking Medicine News(10 mins):Health News:PCMA: New OIG Report Cites Drug Manufacturer“Copay Coupon” Use in Medicare Part D 2Health News:Double Threat in Philippines Displaces Thousands of Unbound Families 2Health News: Cyberbullying Seems to Ramp Up in Middle School 2Health News:New cancer drug target involving lipid chemical messengers 2Health News:Melanoma risk found to have genetic determinant 2
... in U.S., Canada, study says , FRIDAY, April 16 ... places across the United States and Canada could save ... die of cardiac arrest each year, researchers report. , ... in more limited setting, such as casinos or airports, ...
... Inserting new valve within the valve might help high-risk ... -- If an artificial heart valve derived from a ... implanting a mechanical valve inside the artificial valve could ... and opened, the new valve opens and functions similarly ...
... brain lesions developed in patients taking Lipitor than placebo, ... Cholesterol-lowering statin drugs may slow the progression of multiple ... 81 patients with early-stage MS randomly selected to take ... a placebo. After 12 months of treatment, 55.3 percent ...
... Cardiovascular disease appears to be a major risk factor ... -- People with atrial fibrillation, a form of abnormal heart ... Alzheimer,s disease, a new study finds. , The presence of ... especially among younger patients in the group studied, meaning under ...
... Mo. For seniors, dancing isn,t just for fun; ... by University of Missouri researchers found that participation in ... adults. Improved functionality among seniors can decrease their risk ... as dance-based therapy have the potential to significantly reduce ...
... ... ... Researchers at Drexel University College of Medicine have discovered that a certain type ... critical for cancer growth and movement. When researchers reduced and normalized the levels of this ...
Cached Medicine News:Health News:Public Defibrillators Save Lives 2Health News:Public Defibrillators Save Lives 3Health News:Cholesterol Drugs May Slow MS 2Health News:Abnormal Heart Rhythm Linked to Alzheimer's 2Health News:Abnormal Heart Rhythm Linked to Alzheimer's 3Health News:Dance therapy improves seniors' gait, balance, researcher finds 2Health News:Scientists Report Key Finding in Breast Cancer Research 2Health News:Scientists Report Key Finding in Breast Cancer Research 3
(Date:9/19/2014)... -- 4WEB Medical announces the formal launch of the ... on the market today at this weekend,s American ... Chicago .  The Osteotomy Truss System is a ... 74 size options included in one versatile set. Previously ... to 18 implant sizes, which limited a surgeon,s ability ...
(Date:9/19/2014)... , Sept. 19, 2014  Diplomat, the nation,s ... David Dreyer to the Board of Directors ... director and will also serve as chair of the ... 30 years of accounting, financial, compliance and operating experience ... Dreyer has served as chief financial officer, chief operating ...
(Date:9/19/2014)... DALLAS , September 19, 2014 ... Market by Equipment Type (Benchtop, Mobile, Industrial, & ... Others), Technology (Tray-style, Manifold, & Rotary) & Geography ... by MarketsandMarkets, defines and segments the lyophilization market ... regions with analyses and projections of the market ...
Breaking Medicine Technology:4WEB Medical Unveils 3D-Printed Osteotomy Truss System 2David Dreyer Appointed to Diplomat Board of Directors 2Lyophilization Market Worth $5,121.5 Million by 2019 2Lyophilization Market Worth $5,121.5 Million by 2019 3
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: