Navigation Links
New screening method can detect a range of clinical conditions from a single dried blood spot
Date:11/16/2011

has already been successfully used to provide rapid diagnosis of a comprehensive range of inherited metabolic diseases in acutely ill children admitted to intensive care with life-threatening symptoms.
  • Pre-symptomatic screening for chronic health problems will introduce personalised clinical diagnostics and cost-effective early detection and monitoring of diabetes and kidney and heart disease.

    Dried urine spots can also be used for the very early detection of kidney disease, particularly in patients with a high risk of developing renal complications, for example patients with type 1 or type 2 diabetes.

    The test works by converting proteins to peptides and then using a mass spectrometer to select and accurately measure diagnostic metabolites and/or peptides. Liquid blood and urine samples can also be screened using the method.

    Compared with conventional clinical laboratory diagnostics the major advantages of the new method are that the measurements for proteins and metabolites can be done simultaneously with both high accuracy and sensitivity. Dried blood spots and/or dried urine spots offer significant cost savings in the logistics of sample collection, transport to the laboratory, sample processing, and storage.

    Neil Dalton, Professor of Paediatric Biochemistry at King's, and co-founder of SpotOn, said: "The lessons we have learned from universal pre-symptomatic screening of newborn babies using dried blood spots can now be cost-effectively applied to provide a personalised medicine approach to the early diagnosis and clinical monitoring of major chronic health problems like diabetes and kidney and heart disease."


    '/>"/>


  • Contact: Katherine Barnes
    katherine.barnes@kcl.ac.uk
    44-207-848-3076
    King's College London
    Source:Eurekalert

    Page: 1 2

    Related medicine news :

    1. Population-specific community-based cancer screening may discourage smoking
    2. Few doctors follow sudden cardiac death screening guidelines for athletes
    3. Fecal occult blood testing effective in colonoscopy screenings
    4. Birth cohort screening for hepatitis C is cost effective, could save thousands of lives each year
    5. Change in Hepatitis Screening May Save Lives, Money
    6. Research supports broader screening for sudden cardiac death
    7. New research on improved treatment options and screening strategies for Hepatitis C
    8. X-Ray Screening Doesnt Prevent Lung Cancer Deaths: Study
    9. CT scans for lung cancer screening may be beneficial in detecting COPD
    10. Probability model estimates proportion of women who survive breast cancer detected through screening
    11. Cheaper and easier isnt necessarily better in new colon cancer screening procedures
    Post Your Comments:
    *Name:
    *Comment:
    *Email:
    (Date:7/4/2015)... ... July 04, 2015 , ... Earlier in 2015, on Feb. ... annual member survey , detailing the most common plastic surgery and minimally invasive ... raw data down into charts detailing demographic trends and regional preferences. With a ...
    (Date:7/3/2015)... ... ... Food Bank will hopefully be getting a large donation of canned food items at ... SC are making it their mission to collect as many canned items as possible. Donations ... the public as well. As part of the canned food drive, these local chiropractors will ...
    (Date:7/3/2015)... ... 2015 , ... Scientists at several top US cancer centers believe they now ... Click here to read the complete story , just posted on the Surviving ... Medical Center, and New York University exposed mice with a mutation on the tumor ...
    (Date:7/3/2015)... ... July 03, 2015 , ... The ... June 25, 2015 at 1:00pm. The Association welcomed speaker C. Daniel McGillicuddy Esq. ... bicyclists and practical points of investigating these types of cases. , Each year, ...
    (Date:7/3/2015)... ... July 03, 2015 , ... First Choice Emergency Room , ... N. Manzanares, MD as the new Medical Director of its Frisco facility. , “We ... our Frisco facility,” said Dr. James M. Muzzarelli, Executive Medical Director of First Choice ...
    Breaking Medicine News(10 mins):Health News:The ‘South Atlantic’ Frequently Chooses Tummy Tuck for Plastic Surgery, Jacksonville, FL, Doctor Notes 2Health News:The ‘South Atlantic’ Frequently Chooses Tummy Tuck for Plastic Surgery, Jacksonville, FL, Doctor Notes 3Health News:Greenville Area AlignLife Offices to do a Thanksgiving in July Food Drive 2Health News:Greenville Area AlignLife Offices to do a Thanksgiving in July Food Drive 3Health News:Study Finds Small Amounts of Asbestos May Trigger Mesothelioma in People with Genetic Mutation, According to Surviving Mesothelioma 2Health News:Attorney from William Mattar Leads Discussion on Bicycle Accidents 2Health News:First Choice Emergency Room Announces Dr. Mariah N. Manzanares as Medical Director of Frisco, TX Facility 2Health News:First Choice Emergency Room Announces Dr. Mariah N. Manzanares as Medical Director of Frisco, TX Facility 3
    ... A single compound with dual function the ability to ... be used to enhance the diagnosis, imaging and treatment of ... Virginia Tech. Glioblastomas are the most common and aggressive ... These tumor cells often extend beyond the well-defined tumor margins ...
    ... Dotinga HealthDay Reporter , WEDNESDAY, Aug. 3 (HealthDay News) ... research suggests that your life choices might not be the crucial ... it finds that many extremely old people appear to have been ... during their younger years. Of course, don,t take this as ...
    ... Spring Harbor Laboratory (CSHL) and five other institutions have used ... new potential treatment for acute myeloid leukemia (AML). As reported ... have pinpointed a protein called Brd4 as a novel drug ... incurable in 70% of patients. Using a drug compound that ...
    ... New Rochelle, NY, August 3, 2011Positive activity interventions ... to managing depression and may offer hope to ... or have access to adequate medical therapy, according ... Journal of Alternative and Complementary Medicine , a ...
    ... 15 years, Kansas State University researcher Michele Borgarelli has ... there is an interesting twist in his work with ... is similar to the same disease affecting humans, making ... Further proof of the bond between owner and dog? ...
    ... ROCHESTER, Minn. -- Mayo Clinic will receive $10 million ... part of a $220 million grant to its collaborator, ... Republic. The overall award will be used to support ... Center (ICRC) at St. Anne,s and will focus initially ...
    Cached Medicine News:Health News:Researchers develop and test new molecule as a delivery vehicle to image and kill brain tumors 2Health News:Genes, Not Healthy Living, Get Most to Age 100 2Health News:Genes, Not Healthy Living, Get Most to Age 100 3Health News:Unconventional hunt for new cancer targets leads to a powerful drug candidate for leukemia 2Health News:Unconventional hunt for new cancer targets leads to a powerful drug candidate for leukemia 3Health News:Unconventional hunt for new cancer targets leads to a powerful drug candidate for leukemia 4Health News:Harnessing the power of positive thoughts and emotions to treat depression 2Health News:A research tale with a heart to match: Professor looks at cardiovascular disease in dogs 2Health News:A research tale with a heart to match: Professor looks at cardiovascular disease in dogs 3Health News:EU $220 million grant supports Mayo-Czech research using 'space station' approach 2
    (Date:7/2/2015)... -- The Green Exchange, Inc., the developer,s of "Loud Cannabis" ... app that connects cannabis growers directly to patients to ... that their service provides the fastest delivery on the ... half a dozen other delivery apps that have popped ... in that it connects growers directly with patients. ...
    (Date:7/2/2015)... DURHAM, N.C. , July 2, 2015 ... of assets related to the ion channel biology platform ... previously been obtained as part of Pfizer,s 2011 acquisition ... Pfizer,s rights to the "Icagen" name and trademark.  XRPro ... comprehensive services for ion channel and transporter drug discovery, ...
    (Date:7/2/2015)... SHENZHEN, China , 2. Juli 2015 /PRNewswire/ ... Hochdurchsatz-Labor für DNA-Screening in Hongkong vom American ... BGI-Einrichtung in Hongkong ist das erste klinische ... ein CAP-Zertifkat erhält und somit ... Ergänzend zu den bestehenden US FDA - ...
    Breaking Medicine Technology:New Cannabis Delivery App Gets Product to Patient in Under 7 Minutes 2Icagen Re-launched through XRpro Sciences Acquisition of Pfizer Team and Technology for Ion Channel and Transporter Drug R&D 2Icagen Re-launched through XRpro Sciences Acquisition of Pfizer Team and Technology for Ion Channel and Transporter Drug R&D 3Icagen Re-launched through XRpro Sciences Acquisition of Pfizer Team and Technology for Ion Channel and Transporter Drug R&D 4BGI erhält Akkreditierung vom College of American Pathologists (CAP) 2
    ... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
    ... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
    ... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
    ... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
    Medicine Products: