Navigation Links
New screening method can detect a range of clinical conditions from a single dried blood spot
Date:11/16/2011

Scientists have developed a rapid method that can be used to simultaneously screen patients for a range of genetic and acquired clinical conditions from a single dried blood spot.

The test uses a highly sensitive and specific technique, known as mass spectrometry, to simultaneously analyse proteins, enzymes and metabolites in the blood, without the need for the large liquid blood samples currently used. Collection of dried blood spots is less invasive for patients and the costs and biohazards associated with sample transport, processing and storage are minimised.

Researchers at King's College London, together with clinicians from Guy's and St Thomas' NHS Foundation Trust, as part of King's Health Partners Academic Health Sciences Centre, have built on their innovative approaches to dried blood spot screening for inherited metabolic disease and sickle cell disease in newborn babies. This approach can now be used in the early detection and clinical monitoring of chronic health problems, including kidney and heart disease and diabetes.

King's has today officially launched a spin-out company, SpotOn Clinical Diagnostics Ltd, to provide both analytical services and technical support for other clinical laboratories, many of which already have appropriate mass spectrometry instrumentation, to offer this new method.

Requiring only a drop of blood from a simple finger-prick, or heel-prick in newborns, this new blood spot analysis method has many potential applications:

  • The method is faster, more specific, and cheaper than the methods currently used to screen all 750,000 babies born each year in the UK for sickle cell disease and other clinically significant haemoglobinopathies (abnormalities in haemoglobin within the blood). The current methods for ante-natal screening for sickle cell disease and thalassaemia require fresh liquid blood samples, which are more expensive to process, store and transport.
  • The method
    '/>"/>

Contact: Katherine Barnes
katherine.barnes@kcl.ac.uk
44-207-848-3076
King's College London
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Population-specific community-based cancer screening may discourage smoking
2. Few doctors follow sudden cardiac death screening guidelines for athletes
3. Fecal occult blood testing effective in colonoscopy screenings
4. Birth cohort screening for hepatitis C is cost effective, could save thousands of lives each year
5. Change in Hepatitis Screening May Save Lives, Money
6. Research supports broader screening for sudden cardiac death
7. New research on improved treatment options and screening strategies for Hepatitis C
8. X-Ray Screening Doesnt Prevent Lung Cancer Deaths: Study
9. CT scans for lung cancer screening may be beneficial in detecting COPD
10. Probability model estimates proportion of women who survive breast cancer detected through screening
11. Cheaper and easier isnt necessarily better in new colon cancer screening procedures
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/21/2015)... The International Journal of Chronic Obstructive Pulmonary ... and its association with smoking in the Mainland China: ... from ten diverse areas ”. , As corresponding author ... of the world’s cigarettes, but the substantial increases in ... for the full eventual health consequences to be seen. ...
(Date:4/21/2015)... Francisco, CA and Orlando, FL (PRWEB) April 21, ... Behavioral Health (National Council) will honor Dina Tyler, ... Services for PREP (Prevention and Recovery in Early ... National Council Award of Excellence: Peer Specialist of ... awards ceremony, known as the Oscars of behavioral ...
(Date:4/21/2015)... Among parents of children with autism ... as fair or poor, according to a study in ... a visit to the dentist can present many challenges ... the strange smells, loud noises, and sharp tools; the ... of the whole process—not knowing what will happen and ...
(Date:4/21/2015)... The report “Sinusitis – ... on the therapeutic development for Sinusitis. The ... targets and MOAs to produce first-in-class and ... available @ http://www.rnrmarketresearch.com/sinusitis-pipeline-review-h1-2015-market-report.html . , ... in the therapeutic development for Sinusitis and ...
(Date:4/21/2015)... April 21, 2015 Wireless Analytics, ... has been recognized by the Boston Business Journal as ... ranking was announced at a recent event celebrating the ... of the fastest-growing private companies in Massachusetts. , Wireless ... the state that recorded the fastest revenue growth from ...
Breaking Medicine News(10 mins):Health News:COPD and smoking in the Mainland China published by Dove Medical Press 2Health News:COPD and smoking in the Mainland China published by Dove Medical Press 3Health News:The National Council for Behavioral Health Honors Felton Institute’s PREP Program Coordinator with Prestigious Peer Specialist of the Year Award 2Health News:The National Council for Behavioral Health Honors Felton Institute’s PREP Program Coordinator with Prestigious Peer Specialist of the Year Award 3Health News:The National Council for Behavioral Health Honors Felton Institute’s PREP Program Coordinator with Prestigious Peer Specialist of the Year Award 4Health News:Autism Awareness Month: Dental Care Tips for Children With Autism Spectrum Disorder 2Health News:Autism Awareness Month: Dental Care Tips for Children With Autism Spectrum Disorder 3Health News:Autism Awareness Month: Dental Care Tips for Children With Autism Spectrum Disorder 4Health News:Autism Awareness Month: Dental Care Tips for Children With Autism Spectrum Disorder 5Health News:Autism Awareness Month: Dental Care Tips for Children With Autism Spectrum Disorder 6Health News:Sinusitis Therapeutic Development and Pipeline Market Review H1 2015 Available at RnRMarketResearch.com 2Health News:Sinusitis Therapeutic Development and Pipeline Market Review H1 2015 Available at RnRMarketResearch.com 3Health News:Wireless Analytics Ranked as 25th Fastest Growing Private Company in Massachusetts 2
... ask people how much they plan to exercise, they,ll exercise morebut ... in the Journal of Consumer Research . "When people ... in a behavior (say, if the behavior is how much to ... in the next week makes them think about what they think ...
... Today, during the 89th General Session & Exhibition of ... with the 40th Annual Meeting of the American Association ... the Canadian Association for Dental Research, lead researcher Z. ... titled "Fuz is Essential for Craniofacial and Tooth Development." ...
... Today, during the 89th General Session & Exhibition ... conjunction with the 40th Annual Meeting of the American ... of the Canadian Association for Dental Research, lead researcher ... research study titled "Sealing Manifest Occlusal Caries in Permanent ...
... 17 (HealthDay News) -- It,s normal and healthy for ... housing assistance, according to a new study. The ... involves slacker young adults who refuse to grow up ... children,s development, said the researchers. They analyzed data ...
... HealthDay Reporter , THURSDAY, March 17 (HealthDay ... significantly improved the tremors, rigidity and other motor skill ... new study reports. The phase 2 study enrolled ... half randomly assigned to receive the gene therapy and ...
... Researchers at Boston University School of Medicine (BUSM), in ... new biomarker and therapeutic target for melanoma. The novel ... the process behind tumor metastasis and may allow the ... now appear online in Cancer Research . ...
Cached Medicine News:Health News:Getting healthy: When does prediction help people change their habits? 2Health News:Sealing manifest occlusal caries in permanent teeth -- 2.5-year results 2Health News:Young Adults May Need 'Safety Net' 2Health News:Gene Therapy May Help Reverse Parkinson's Symptoms 2Health News:Gene Therapy May Help Reverse Parkinson's Symptoms 3Health News:Researchers discover possible biomarker and therapeutic target for melanoma 2
(Date:4/21/2015)... The non-invasive & minimally invasive cardiac output monitoring devices market is estimated ... Europe is segmented as Germany , U.K., ... Rest of Europe (RoE). Germany holds ... cardiac output monitoring devices market around 35.2% in 2014 followed by France ... , Sweden , Poland , Switzerland ...
(Date:4/21/2015)... 21, 2015 Whitehall-based ... dazzling export-led growth in just 4 years. ... part in winning the Queen,s Award for Enterprise, ... Oxford PharmaGenesis. As part of the world,s first ... bring new medicines to the world in areas ...
(Date:4/21/2015)... 2015 This report analyzes the worldwide markets ... Types: Equipment for Therapeutic Apheresis, and Equipment for Donor ... Erythrocytapheresis, Plasmapheresis, Plateletpheresis, and Others. The report provides separate ... , Japan , Europe ... of World. Annual estimates and forecasts are provided for ...
Breaking Medicine Technology:European Non-invasive and Minimally Invasive Cardiac Output Monitoring Devices Market by Type, by End-User - Forecast to 2019 2European Non-invasive and Minimally Invasive Cardiac Output Monitoring Devices Market by Type, by End-User - Forecast to 2019 3Queen's Award Crowns Achievements of Fast-growing London Consultancy 2Queen's Award Crowns Achievements of Fast-growing London Consultancy 3Queen's Award Crowns Achievements of Fast-growing London Consultancy 4Queen's Award Crowns Achievements of Fast-growing London Consultancy 5World Apheresis Equipment Industry 2World Apheresis Equipment Industry 3World Apheresis Equipment Industry 4World Apheresis Equipment Industry 5World Apheresis Equipment Industry 6World Apheresis Equipment Industry 7World Apheresis Equipment Industry 8World Apheresis Equipment Industry 9World Apheresis Equipment Industry 10World Apheresis Equipment Industry 11World Apheresis Equipment Industry 12World Apheresis Equipment Industry 13World Apheresis Equipment Industry 14World Apheresis Equipment Industry 15World Apheresis Equipment Industry 16World Apheresis Equipment Industry 17World Apheresis Equipment Industry 18World Apheresis Equipment Industry 19World Apheresis Equipment Industry 20World Apheresis Equipment Industry 21
... CAUSE NO. 2010-10259, , BRAD KOVNAT, ... , ... , v. ... , THE PALLADIUM FOR SURGERY- ...
... BRISBANE, Calif. , Feb. 17 InterMune, Inc. ... the fourth quarter and 12 months ended December 31, ... business activities, and previewed upcoming milestones in 2010.   , ... of InterMune said, "Fourth quarter and recent events have been ...
Cached Medicine Technology:Texas Court Asked to Appoint Receiver for Key Subsidiary of TSX Listed Northstar Healthcare, Inc. (TSX NHC) on Claims of Mismanagement and Breach of Fiduciary Duty 2Texas Court Asked to Appoint Receiver for Key Subsidiary of TSX Listed Northstar Healthcare, Inc. (TSX NHC) on Claims of Mismanagement and Breach of Fiduciary Duty 3Texas Court Asked to Appoint Receiver for Key Subsidiary of TSX Listed Northstar Healthcare, Inc. (TSX NHC) on Claims of Mismanagement and Breach of Fiduciary Duty 4Texas Court Asked to Appoint Receiver for Key Subsidiary of TSX Listed Northstar Healthcare, Inc. (TSX NHC) on Claims of Mismanagement and Breach of Fiduciary Duty 5Texas Court Asked to Appoint Receiver for Key Subsidiary of TSX Listed Northstar Healthcare, Inc. (TSX NHC) on Claims of Mismanagement and Breach of Fiduciary Duty 6Texas Court Asked to Appoint Receiver for Key Subsidiary of TSX Listed Northstar Healthcare, Inc. (TSX NHC) on Claims of Mismanagement and Breach of Fiduciary Duty 7Texas Court Asked to Appoint Receiver for Key Subsidiary of TSX Listed Northstar Healthcare, Inc. (TSX NHC) on Claims of Mismanagement and Breach of Fiduciary Duty 8Texas Court Asked to Appoint Receiver for Key Subsidiary of TSX Listed Northstar Healthcare, Inc. (TSX NHC) on Claims of Mismanagement and Breach of Fiduciary Duty 9InterMune Reports Fourth Quarter and Full Year 2009 Financial Results and Business Highlights 2InterMune Reports Fourth Quarter and Full Year 2009 Financial Results and Business Highlights 3InterMune Reports Fourth Quarter and Full Year 2009 Financial Results and Business Highlights 4InterMune Reports Fourth Quarter and Full Year 2009 Financial Results and Business Highlights 5InterMune Reports Fourth Quarter and Full Year 2009 Financial Results and Business Highlights 6InterMune Reports Fourth Quarter and Full Year 2009 Financial Results and Business Highlights 7InterMune Reports Fourth Quarter and Full Year 2009 Financial Results and Business Highlights 8InterMune Reports Fourth Quarter and Full Year 2009 Financial Results and Business Highlights 9InterMune Reports Fourth Quarter and Full Year 2009 Financial Results and Business Highlights 10InterMune Reports Fourth Quarter and Full Year 2009 Financial Results and Business Highlights 11InterMune Reports Fourth Quarter and Full Year 2009 Financial Results and Business Highlights 12
The Model 340DT is a new desk top pulse oximeter that was designed for continuous pulse oximetry and has visual and audible alarms to aid with patient monitoring....
... has expanded memory capabilities for overnight sleep screening., ... oxygen saturation and pulse rate data, and can ... your needs:, ,1. The Model 130 can ... a single patient, making the device ideally suited ...
... Cost-effective, portable, continuous, or ... system with alarms and an ... Home-Use and Sleep Study modes ... in the hospital or clinical ...
... The Autocorr Plus, the fourth in ... versatile pulse oximeter/ECG/Respiration Monitor, with 3 ... digital oximetry with SAC (Serial Autocorrelation) ... electroluminescent screen display provides two user ...
Medicine Products: