Navigation Links
New risk variant for atopic dermatitis identified
Date:4/6/2009

Scientists of the Max Delbrck Center for Molecular Medicine (MDC) Berlin-Buch and Charit University Medical School, Berlin, Germany, in collaboration with researchers from the Klinikum rechts der Isar of Technical University Munich and Christian Albrecht University, Kiel, have identified a gene variant on chromosome 11 that is associated with an increased risk of atopic dermatitis. In a large genome-wide association study the researchers scanned the genomes of more than 9600 participants from Germany, Poland and the Czech Republic. "Our findings cast new light on the pathogenesis of the disease," said Professor Young-Ae Lee (Charit / MDC). The pediatrician-researcher and her collaborators hope the study will lead to a new approach to targeted therapy for this chronic skin disorder. (Nature Genetics doi: 10.1038/ng.347)*.

More and more people suffer from atopic dermatitis, which is also known as atopic or infantile eczema. Atopic dermatitis is a chronic (long-lasting) inflammatory skin disease that typically affects the large flexures such as the bend of the elbows or the back of the knees. Patients suffer from recurrent flares of intense itching, dryness and redness of the skin, with weeping of clear fluid in the acute stage, and skin thickening (lichenification) in the chronic stage. Along with hay fever and asthma, atopic dermatitis is one of the most common allergic disorders. In the industrialized countries about 15 percent of young children are affected.

Atopic dermatitis is typically the first clinical manifestation of allergic disease. In most cases atopic dermatitis appears within the first few years of life. For the majority of affected children this marks the beginning of an "allergic career", which in later years evolves into hay fever or asthma. Just what triggers the outbreak of atopic dermatitis is not yet fully understood. However, epidemiological studies indicate that the genetic contribution is substantial.

F
'/>"/>

Contact: Barbara Bachtler
bachtler@mdc-berlin.de
49-309-406-3896
Helmholtz Association of German Research Centres
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Study IDs Gene Variants Tied to Sudden Cardiac Death
2. Gene Variant Tied to Cocaine-Induced Paranoia
3. Gene Variant Allies Autism, Gastrointestinal Woes
4. Gene Variant Raises Risk of Uterine Fibroids
5. Gene Variant Tied to Severity of Drinking
6. Gene Variant Raises Risk for Brain Cancer at Young Age
7. Gene Variant May Hike Womens Risk of Alzheimers
8. Biologist finds plant polymerases IV and V are really variants of Polymerase II
9. Gene Variant Tied to Smokers Risk of Lung Cancer
10. Genetic Variants Tied to Obesity
11. NEW Line of Pushbutton Pill Cases Launched by Variant Products
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... ... July 31, 2015 , ... The Heart Fit Clinic has increased a ... a heart rate of 150 beats versus 100 beats, this is a big deal," ... to give life back to patients with heart disease," he adds. People with angina ...
(Date:7/31/2015)... ... , ... Ticket Down is a reputable source of authentic USA vs. ... will face the Australia Women's National Team in two separate friendly contests. The ... and the second match will occur in Birmingham, Alabama at Legion Field. These ...
(Date:7/31/2015)... ... 31, 2015 , ... Healthpointe , a multidisciplinary health ... at Healthpointe.net. The new website will feature a sleek and streamlined design built ... provide smoother interactions between patients and the Healthpointe clinics and ensures that appointments ...
(Date:7/31/2015)... , ... July 31, 2015 , ... Physical therapy for knee osteoarthritis ... patient's quality of life. It keeps the patient from doing what they want or need ... have a hard time using the stairs. The patient's exercise regime may be limited by ...
(Date:7/31/2015)... (PRWEB) , ... July 31, 2015 , ... ... of All Types " from NBC talked about a woman’s unfortunate experience having ... performed sclerotherapy on her face, which resulted in blistering, swelling, bruising, and pain. ...
Breaking Medicine News(10 mins):Health News:Heart Fit Clinic Helps Patient Increase Fitness Level with External Counterpulsation 2Health News:Cheap USA vs. Australia Tickets at Legion Field in Birmingham, AL: Ticket Down Slashes Ticket Prices for Australia vs. USWNT at Legion Field 2Health News:Healthpointe Announces Newly Redesigned Website 2Health News:NYDNRehab Is the First Clinic in NYC to Provide APOS Therapy Based on Results of Complete Gait Analysis 2Health News:NYDNRehab Is the First Clinic in NYC to Provide APOS Therapy Based on Results of Complete Gait Analysis 3Health News:Dermatologists Discuss Rise in Unqualified Practitioners of Cosmetic Dermatology 2Health News:Dermatologists Discuss Rise in Unqualified Practitioners of Cosmetic Dermatology 3
... drink the most, study finds, , FRIDAY, March 5 ... raises the likelihood that people will suffer flashbacks, but ... what happened, new research suggests. , The findings could ... disorder and others don,t, noted the authors of the ...
... devices or patient error, FDA panel says , FRIDAY, March ... to treat diabetes should try to supply more information to ... devices, an advisory panel to the U.S. Food and Drug ... to report when a device malfunctions or may have contributed ...
... Both ... Protection to form a global campaign representing millions of people to affect bold action on ... Washington, DC ... transition to a clean energy economy and heal the planet, the Alliance for Climate Protection ...
... ... ... ... ...
... ... ... ... ...
... illness , FRIDAY, March 5 (HealthDay News) -- U.S. researchers ... act like related illnesses, such as mad cow disease, but ... disease. , It is not yet clear what the finding ... mice, the study authors noted in the report published online ...
Cached Medicine News:Health News:Alcohol Influences How Memorable Trauma Might Be 2Health News:More Info Needed on Problems With Insulin Pumps 2Health News:More Info Needed on Problems With Insulin Pumps 3Health News:National Climate Organizations Join Forces In Historic Push For Climate and Clean Energy Solutions 2Health News:National Climate Organizations Join Forces In Historic Push For Climate and Clean Energy Solutions 3Health News:Pennsylvania to Observe 'Problem Gambling Awareness Week'; Remind Residents of Available Counseling and Treatment Services 2Health News:Pennsylvania to Observe 'Problem Gambling Awareness Week'; Remind Residents of Available Counseling and Treatment Services 3Health News:Pennsylvania to Observe 'Problem Gambling Awareness Week'; Remind Residents of Available Counseling and Treatment Services 4Health News:Pennsylvania to Observe 'Problem Gambling Awareness Week'; Remind Residents of Available Counseling and Treatment Services 5Health News:Pennsylvania to Observe 'Problem Gambling Awareness Week'; Remind Residents of Available Counseling and Treatment Services 6Health News:Lippincott Williams & Wilkins Introduces The Editors Handbook: An Online Resource and CE Course 2Health News:Lippincott Williams & Wilkins Introduces The Editors Handbook: An Online Resource and CE Course 3Health News:Lippincott Williams & Wilkins Introduces The Editors Handbook: An Online Resource and CE Course 4Health News:Lippincott Williams & Wilkins Introduces The Editors Handbook: An Online Resource and CE Course 5Health News:Lippincott Williams & Wilkins Introduces The Editors Handbook: An Online Resource and CE Course 6Health News:Lippincott Williams & Wilkins Introduces The Editors Handbook: An Online Resource and CE Course 7Health News:Lippincott Williams & Wilkins Introduces The Editors Handbook: An Online Resource and CE Course 8
(Date:7/30/2015)... WASHINGTON , July 30, 2015  Today we bring you a special edition ... wanted to remind you about some of our Medicare resources and continue highlighting the ... Check out our latest infographics and videos ... ... ...
(Date:7/30/2015)... VANCOUVER , July 30, 2015  OncoGenex Pharmaceuticals, ... will report its second quarter 2015 financial results on ... conference call and live webcast at 4:30 p.m. Eastern ... development programs and a general corporate update. ... Investor Relations page of the OncoGenex website at ...
(Date:7/30/2015)... PLAINFIELD, N.J., July 30, 2015 PTC Therapeutics, ... update and reported financial results for the second quarter ... progressing on many fronts across the organization.  We are ... Duchenne muscular dystrophy clinical trial ever conducted with topline ... Peltz, Ph.D., Chief Executive Officer, PTC Therapeutics, Inc. "Translarna ...
Breaking Medicine Technology:Happy 50th Anniversary Medicare! 2Happy 50th Anniversary Medicare! 3PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 2PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 3PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 4PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 5PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 6PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 7PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 8PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 9PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 10
... LOS ANGELES, Sept. 12, 2011 Cytta Corp (OTCQB: ... successfully completed the first client installation and deployment of ... Company to commence a full scale roll out of ... payors and providers, such as: Health Plans, Managed Care ...
... - Digital issue looks inside the ... The Journal of Emergency Medical Services ( ... four-volume digital issue featuring first-person accounts of responders who were ... 2001, when terrorists invaded their response districts - and their ...
Cached Medicine Technology:First Client Installation of CyttaConnect™ Medical Monitoring System 2First Client Installation of CyttaConnect™ Medical Monitoring System 3Out of the Darkness 2Out of the Darkness 3
10-mm (0.4-in) diameter cups have multi-color lead wires and 2-mm (0.08-in) holes for easy paste/collodion application. Available in a variety of lengths to suit many different needs....
... Made with elastic fabric, these head cap ... need to begin testing. Each Electro-Cap System ... the International 10-20 System. When you place ... are using with your head cap system ...
... Made with elastic fabric, these head ... you need to begin testing. Each Electro-Cap ... to the International 10-20 System. When you ... you are using with your head cap ...
... head cap systems are packaged to provide ... Electro-Cap System features pure tin electrodes positioned ... you place your order, please specify which ... cap system and whether you want regular ...
Medicine Products: