Navigation Links
New research tools are too complex for easy answers, researchers say
Date:12/27/2007

Washington, D.C. − Scientists who study cancer may be prone to drawing simplistic conclusions from the powerful molecular tools now available because they dont appreciate how complex the data is that is being generated, said a team of Georgetown University Medical Center (GUMC) researchers in the January issue of Nature Reviews Cancer.

In a review article summing up the state of the field, they said cancer investigators should endeavor to better understand the issues these genomic and proteomic technologies create or conclusions from their research may be misleading.

These tools have allowed us to see that nature is more complex than we thought, and while we dont yet know what the overarching biological rules are − such as the interrelationship between multiple signaling pathways that can lead to cancer development − we are trying to play the game like we do, said the reviews lead author, Robert Clarke, Ph.D., D.Sc., professor of oncology and physiology & biophysics at the Lombardi Comprehensive Cancer Center at GUMC, where he co-directs the Breast Cancer Program. Clarke is the interim director of GUMCs Biomedical Graduate Research Organization, which is home to more than 60 percent of the Universitys biomedical research funding.

The answers to our questions are probably there in the data, he said, but the issue is whether we can get them using these complex tools and, also, how we will know they are right when we see them.

Clarke led the analysis with six other scientists from Georgetown and from Virginia Polytechnic Institute. GUMC is pioneering a field of systems medicine study designed to understand the theory and properties of the data generated by these new tools and how they may affect data analysis and interpretation.

This review addresses the challenges in reducing high-dimensional molecular data and making the output relevant to cancer treatment, said Dr. Howard Federoff, executive vi
'/>"/>

Contact: Becky Wexler
rjw43@georgetown.edu
202-687-5100
Georgetown University Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. Children of depressed moms do better when dad is involved, SLU researcher finds
3. UCLA researchers identify markers that may predict diabetes in still-healthy people
4. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
5. New research shows how chronic stress worsens neurodegenerative disease course
6. New research explores newborn in-hospital weight loss
7. Research may unlock mystery of autisms origin in the brain
8. Bipolar disorder relapses halved by Melbourne researchers
9. HIVs impact in Zimbabwe explored in new research
10. U.S. Research Funding Continues to Flatten as U.S. Health Costs Climb - in August 31 Science
11. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... Recently, UWDress.com, the distinguished wedding dress manufacturer and ... party dresses for girls . According to the company’s ... handmade by experienced specialists. Now, they are provided with ... company’s new items come in various styles: A-line scalloped ... long elegant backless gowns and so on. It is ...
(Date:8/20/2014)... An Elle Magazine online report dated August ... Looking Young at Every Age,” offers a set of recommendations ... . These recommendations are offered as a preventative skincare ... 25-45 and beyond. The first group of recommendations can be ... includes using sunscreen religiously, getting sufficient exercise and sleep, and ...
(Date:8/20/2014)... August 20, 2014 Today, Zane ... the publication of a new eBook, Affordable Care ... small business owners feel uncertain about how the ... and their bottom line. , The new eBook ... helps businesses navigate their upcoming health insurance decisions. ...
(Date:8/20/2014)... (PRWEB) August 20, 2014 Ticket Down ... tickets in NYC. In just a week, the U.S. ... King Tennis Center. The event was originally founded in 1881 and ... Rafael Nadal was forced to withdrawal from the event because of ... women’s tournament and will return to New York City with hopes ...
(Date:8/20/2014)... Dennis Thompson HealthDay Reporter ... experimental drug has saved a group of rhesus monkeys from ... that kills up to 90 percent of those it infects, ... lethal doses of Marburg virus, even when it was given ... 20 in the journal Science Translational Medicine . ...
Breaking Medicine News(10 mins):Health News:Cheap Birthday Party Dresses for Girls Now Available at UWDress.com 2Health News:Simon Ourian, Kim Kardashian’s Doctor, On Healthy Skin Suggestions for Every Age 2Health News:2014 U.S. Open Tennis Tickets: Ticket Down Slashes Ticket Prices on All US Open Tennis Championship Sessions in New York at Arthur Ashe Stadium 2Health News:2014 U.S. Open Tennis Tickets: Ticket Down Slashes Ticket Prices on All US Open Tennis Championship Sessions in New York at Arthur Ashe Stadium 3Health News:2014 U.S. Open Tennis Tickets: Ticket Down Slashes Ticket Prices on All US Open Tennis Championship Sessions in New York at Arthur Ashe Stadium 4Health News:2014 U.S. Open Tennis Tickets: Ticket Down Slashes Ticket Prices on All US Open Tennis Championship Sessions in New York at Arthur Ashe Stadium 5Health News:Drug for Ebola-Like Virus Shows Promise in Monkeys 2Health News:Drug for Ebola-Like Virus Shows Promise in Monkeys 3
... fill gaps and offset rising employee-paid healthcare costs. , ... ... employers have completed their annual benefit enrollment period, Combined Insurance ... insurance benefits and coverage to identify potential gaps in coverage due ...
... , ... Cincinnati, OH (PRWEB) February ... an innovative solution to a pressing health care concern – ... medication therapy., , ,This concern was underscored in a recent ...
... Raw Materials CatalogST. LOUIS, Feb. 10 SAFC Supply ... the Sigma-Aldrich Group (Nasdaq: SIAL ) ... today announced that it has added 50 new Certified ... materials product line. Details of the new products ...
... rBGH milk from Yoplait Yogurt."SAN FRANCISCO, Feb. 9 ... watchdog of the breast cancer movement - today ... General Mills remove the cancer-linked synthetic growth hormone, ... of BCA,s 2008 "Think Before You Pink" campaign ...
... Publish Study Defining Mechanism,and Potential Treatment for Rett Syndrome, ... Clinical trial to test molecule in humans is being ... apply to other forms of autism - , BOSTON ... innovative research, clinical and family collaboration dedicated to radically ...
... Feb. 9 Ten health professional students pursuing ... and $2,000 scholarships from the National Hispanic Health ... Professional Student Scholarship Gala at the Sheraton Grand ... keynote speaker will be the Honorable Dean Florez, ...
Cached Medicine News:Health News:Leading Supplemental Insurer Recommends Insurance Review Following Annual Benefit Enrollment Period 2Health News:Leading Supplemental Insurer Recommends Insurance Review Following Annual Benefit Enrollment Period 3Health News:AdherenceRx Partners with Hummingbird Coaching To Increase Patient Medication Adherence 2Health News:AdherenceRx Partners with Hummingbird Coaching To Increase Patient Medication Adherence 3Health News:SAFC Supply Solutions Introduces Certified Organics to Flavors & Fragrances Product Line 2Health News:SAFC Supply Solutions Introduces Certified Organics to Flavors & Fragrances Product Line 3Health News:SAFC Supply Solutions Introduces Certified Organics to Flavors & Fragrances Product Line 4Health News:Breast Cancer Action Victorious in Yoplait 'Pinkwashing' Campaign 2Health News:Autism Consortium members publish in PNAS: Mechanism, treatment for Rett syndrome -- top cause autism girls 2Health News:Autism Consortium members publish in PNAS: Mechanism, treatment for Rett syndrome -- top cause autism girls 3Health News:NHHF Scholarship Program Targets Growing Demand for Diversity Among Health Care Professionals 2
(Date:8/20/2014)... Aug. 20, 2014  The National Association of ... results achieved by the real-time, pseudoephedrine (PSE) blocking ... Precursor Log Exchange (NPLEx), automatically blocks unlawful PSE ... meth offenders and make arrests. Data released by ... blocked the sale of more than ...
(Date:8/20/2014)...  The National Association of Drug Diversion Investigators ... the real-time, pseudoephedrine (PSE) blocking system in Missouri. The ... (NPLEx), automatically blocks unlawful pseudoephedrine sales and helps ... make arrests. Data released by NPLEx shows electronic ... the sale of more than 19,030 boxes of medicine ...
(Date:8/20/2014)... , Aug. 20, 2014 PTC Therapeutics, Inc. (NASDAQ: ... two upcoming investor conferences: - FBR 1 st ... Boston on Wednesday, September 3 rd ... The Mandarin Oriental Boston on Thursday, September 4 th ... update at the Bank of America Merrill Lynch Global Healthcare ...
Breaking Medicine Technology:Kentucky's Stop-Sale System Achieves Significant Results In Battle Against Meth 2Missouri's Stop-Sale System Achieves Significant Results In Battle Against Meth 2PTC Therapeutics to Participate at Upcoming Investor Conferences 2
... CINCINNATI, Jan. 12, 2012   Prasco® Laboratories announced today ... (NASDAQ: SHPGY ) for the distribution ...   version of Carbatrol® (Carbamazepine) Extended-Release Capsules in 100 ... Carbamazepine Extended-Release Capsules are AB-rated, therapeutically equivalent and ...
...   Optimer Pharmaceuticals, Inc. (NASDAQ: ... Ph.D., Chief Operating Officer & Senior Vice President, ... other interests. (Logo:  http://photos.prnewswire.com/prnh/20090413/LA97352LOGO ... been a great experience building Optimer Pharmaceuticals and bringing ...
Cached Medicine Technology:Prasco® Launches Authorized Generic of Shire's Carbatrol® 2Prasco® Launches Authorized Generic of Shire's Carbatrol® 3Prasco® Launches Authorized Generic of Shire's Carbatrol® 4Chief Operating Officer Tessie M. Che Departing Company 2Chief Operating Officer Tessie M. Che Departing Company 3
Security and confidence assured with porous tape; integral deodorizing/venting filter....
Inquire...
Inquire...
Superior Skin Care...Convex FlexWear skin barrier is secure and provides extended weartime. Security and confidence assured with internal non-reflux valves and a drain valve that allows regulation of...
Medicine Products: