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New research suggests hearts are experts at self-preservation
Date:9/30/2007

otect hearts with coronary disease.

An exciting observation was also made when normal mice were fed the same Western-type high-fat diet. These mice do not develop coronary disease and their hearts appear to function normally. However, when hearts from these mice were starved of blood supply such as in a heart attack or during surgery - they were found to be much more vulnerable to injury than hearts of similar mice fed normal diet. This is in complete contrast to the disease-prone animals and suggests that Western style high-fat diet can significantly weaken the internal defences of the otherwise normally working heart and render it vulnerable to any sudden stress. Therefore the Western-style diet is truly ugly for disease prone hearts and it is also bad for healthy hearts.

Professor Suleiman, said: "We have shown that in mice prone to developing coronary artery disease, a Western-style diet accelerates the progression of disease but that hearts with coronary disease then became more resistant to further damage, such as occurs during surgery. But it is still better to avoid surgery altogether by adopting healthy eating habits!"


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Contact: Joanne Fryer
joanne.fryer@bristol.ac.uk
44-117-331-7276
University of Bristol
Source:Eurekalert

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