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New research shows cardiologists can quickly detect significant coronary artery disease using a non-invasive simple, short respiratory stress test
Date:5/13/2010

Tel Aviv, Israel, May 13, 2010 Newly published data confirm a non-invasive Respiratory Stress Response (RSR) can quickly and accurately measure the presence of significant coronary artery disease (sCAD), the leading cause of cardiovascular death worldwide. Patients in the study with sCAD had a lower RSR compared to patients without. These data, published in the current issue of The American Journal of the Medical Sciences, demonstrate that RSR was significantly lower in patients with sCAD compared to those with non-significant CAD (P< 0.001), and yielded a sensitivity of 83% (CI 95% = 75-90) and specificity of 70% (CI 95% = 59-80). In multivariable analysis RSR was found to be an independent marker of S-CAD, far stronger than other traditional risk factors.

Researchers at Barzilai Medical Center used the innovative RSR developed by SPIROCORTM Ltd. The test uses a Pulse Oximeter (PPG) to measure a patient's blood flow in the finger in response to his or her paced breathing for 70 seconds. PPG data captured in the study are recorded immediately and analyzed using a proprietary algorithm that determines the RSR in a percent value. The findings of this study were further validated in research recently published in Euro Intervention Journal and Cardiovascular Revascularization Medicine.

"Currently available noninvasive tests for the detection of CAD are expensive, time consuming, involve exposure to ionized radiation in some tests, and require highly trained personnel," said Professor Amos Katz, Director, Department of Cardiology, Barzilai Medical Center, Ashkelon, Israel, and Faculty of Health Sciences, Ben-Gurion University, Israel. "This study shows that the SPIROCOR test is a simple, non-invasive and less time-consuming test that independently predicts significant coronary artery disease in patients referred for a coronary artery evaluation."

The test is not yet cleared for use in the US. The safety and efficacy of the test co
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Contact: Terry Pizinger
Terry.Pizinger@spirocor.com
770-880-5050
Edelman Public Relations
Source:Eurekalert

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