Navigation Links
New research seeks to improve survival for myeloma and lymphoma patients
Date:7/25/2012

Researchers at the University of York are launching a major study of lymphoma and myeloma aimed at promoting earlier diagnosis and improving survival for patients with these cancers, which are among the most common in the UK.

The project, which is funded by Cancer Research UK as part of the National Awareness and Early Diagnosis Initiative (NAEDI), will develop an evidence base that could be used to reduce time-to-diagnosis in patients with these types of cancers.

Led by Dr Debra Howell of the Epidemiology and Genetics Unit in the University's Department of Health Sciences, the 300,000 study is prompted by data indicating that survival for many cancers is poorer in the UK than Europe.

Dr Howell says: "The UK Improving Outcomes Guidance for cancer considers that the most important reason for this is likely to be late stage diagnosis; earlier diagnosis may increase the scope for successful treatment and could save thousands of lives.

"There are nearly 15,000 new diagnoses annually of lymphoma (Hodgkin and non-Hodgkin) and myeloma in the UK, and early diagnosis is complicated by the complex nature of these diseases. The symptoms of lymphoma and myeloma can be strikingly similar to those of more common, benign conditions and this poses exacting challenges for both patients and GPs when identifying symptoms that may indicate malignancy. This situation often leads to delayed help-seeking and prevents early hospital referral."

Patients said:

"The doctors were concerned about these swollen glands in my neck which I'd had for a couple of months. I never thought anything about it because they didn't hurt."

"I just thought it was a swollen gland. It could have been an infection of the throat."

"I got the lump taken away and the doctor said I'm sorry to have to say that it's lymphoma. But prior to that I hadn't felt poorly. Nothing. I've had no symptoms. I've not been poorly at all really."

Despite UK Referral Guidance, data from the National Cancer Data Repository (2007) reported that patients with haematological malignancies, including lymphoma and myeloma, were generally more often diagnosed after emergency presentation and less often referred via the Government recommended two-week wait compared to those with other cancers.

The new study will include a cohort of around 1000 patients newly diagnosed with lymphoma or myeloma during 2012.

Its specific objectives are to:

  • interview patients to explore their symptoms before diagnosis, how they reacted to these and from whom they sought help
  • use primary care (GP) and hospital records to examine events between patients seeking help and diagnosis, such as GP appointments and hospital referrals

The evidence generated will inform UK clinical guidance and could be used to develop tools such as computer-based decision programmes to help GPs to identify patients with these cancers. This could help to promote appropriate investigation and referral, reduce time-to-diagnosis and improve survival outcomes. Educational resources will also be produced to encourage people with possible symptoms to seek help sooner.

The study is based on the infrastructure of the Haematological Malignancy Research Network (HMRN), which was established in 2004. HMRN is a specialist population-based registry, funded by Leukaemia and Lymphoma Research (LLR), which includes all patients newly diagnosed with a haematological malignancy within the Yorkshire and Humber and the Yorkshire Coast Cancer Network areas more than 2,000 new diagnoses from a population of 3.6 million each year.

Dr Howell adds: "As the HMRN area is representative of the UK as a whole in terms of both demography and clinical practice, the results could inform practice around the UK."


'/>"/>
Contact: David Garner
david.garner@york.ac.uk
44-019-043-22153
University of York
Source:Eurekalert

Related medicine news :

1. Adolescent sexual behavior tied to motion picture sexual content exposure, says MU researcher
2. John Theurer Cancer Center researchers shed light on new multiple myeloma therapy
3. Mount Sinai researchers discover new target for vaccine development in abundant immune cells
4. Researchers study vaccine as potential weapon against aggressive brain tumors
5. Researchers developing bioadhesive gel to protect women from HIV and HSV infections
6. Researchers find driver of breast cancer stem cell metastasis
7. Researchers unfold the mechanisms underlying blood disorders
8. Research shows potential of microneedles to target therapeutics to the back of the eye
9. New findings by GW researcher break tanning misconceptions: There is no such thing as a safe tan
10. Tel Aviv University research links childhood obesity to cancer risk
11. New lipid screening guidelines for children overly aggressive, UCSF researchers say
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... D.C. (PRWEB) , ... June 25, 2016 , ... ... discuss health policy issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, ... their work on several important health care topics including advance care planning, healthcare ...
(Date:6/25/2016)... Lewisville, TX (PRWEB) , ... June 25, 2016 , ... ... in the United States, named Dr. Sesan Ogunleye, as the Medical Director of its ... be the facility Medical Director of our new Mesquite location,” said Dr. James M. ...
(Date:6/25/2016)... Canada (PRWEB) , ... June 25, 2016 , ... Conventional ... pursuit of success. In terms of the latter, setting the bar too high can ... risk more than just slow progress toward their goal. , Research from ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. Her son ... lash out at his family verbally and physically. , “When something upset him, he couldn’t ... would use it. He would throw rocks at my other children and say he was ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, ... and the Road To Recovery® program to drive cancer patients to and from their ... to ensure the highest quality of life and ongoing independence. Getting to and ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Tenn. , June 24, 2016  Arkis ... providing less invasive and more durable cerebrospinal fluid ... in funding.  The Series-A funding is led by ... Lighthouse Fund, and other private investors.  Arkis, new ... neurosurgical instrumentation and the market release of its ...
(Date:6/23/2016)... Research and Markets has announced the addition ... Chemical (Sugar, Petrochemical, Glycerin), Inorganic Chemical), Functionality (Filler, Binder, ... Forecast to 2021" report to their offering. ... excipients market is projected to reach USD 8.1 Billion ... forecast period 2016 to 2021. The ...
(Date:6/23/2016)... , June 23, 2016 ... CAPR ), a biotechnology company focused on the ... announced that patient enrollment in its ongoing randomized ... has exceeded 50% of its 24-patient target. Capricor ... the third quarter of 2016, and to report ...
Breaking Medicine Technology: