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New research may lead to earlier diagnosis and treatment of primary biliary cirrhosis in families
Date:9/10/2007

onstantinos Lazaridis, M.D., the studys lead author and a hepatologist at Mayo Clinic. Because collectively one in five sisters of a PBC patient has anti-mitochondrial antibodies in their blood, we think it is worthwhile to screen first-degree relatives, particularly those older than 40 years, for this biomarker. It is a simple, inexpensive blood test that could lead to earlier diagnosis and treatment -- and ultimately, better outcomes for PBC patients.

According to Dr. Lazaridis, the studys findings regarding anti-mitochondrial antibodies in PBC relatives could also be important to better understanding the known genetic predisposition to PBC. His research team plans to continue screening and monitoring first-degree relatives of PBC patients over many years to further examine these findings and to shed light on the cause of this disease.


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Contact: Elizabeth Rice
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

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