Navigation Links
New research may lead to earlier diagnosis and treatment of primary biliary cirrhosis in families
Date:9/10/2007

ROCHESTER, Minn. -- Mayo Clinic researchers have found that first-degree relatives (i.e., parents, siblings, children) of patients with primary biliary cirrhosis (PBC) are more likely to have the biomarker of the disease in their blood. Armed with this new information, physicians could screen and assess first-degree relatives of PBC patients with a simple blood test, enabling them to diagnose and treat more patients before the disease causes irreversible liver damage. These findings were published in this months issue of Hepatology.

PBC is a chronic liver disease that affects nearly 50,000 people (primarily women) in North America. In individuals who have PBC, the bile ducts are slowly destroyed, causing harmful substances to build up in the liver and sometimes resulting in irreversible scarring of liver tissue and liver failure. About half of PBC patients have no symptoms and are diagnosed following abnormal results of routine liver tests.

Anti-mitochondrial antibodies are the biomarker, or the substance that correlates with the risk or presence of a disease, for PBC. This study, the largest of its kind, tested for anti-mitochondrial antibodies in 306 first-degree relatives of adult PBC patients and 196 healthy adults. The prevalence in first-degree relatives was 13.1 percent, compared to 1 percent in the control group of healthy adults. Even greater prevalence was found in female relatives, with 20.7 percent of sisters, 15.1 percent of mothers and 9.8 percent of daughters having anti-mitochondrial antibodies in their blood. While testing positive for anti-mitochondrial antibodies does not always lead to a diagnosis of PBC, the presence of these antibodies indicates a predisposition to develop the illness, particularly in the context of family history of the disease.

Most PBC patients have no symptoms, but early detection is important because timely treatment can slow the progression of the disease before liver failure occurs, says K
'/>"/>

Contact: Elizabeth Rice
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Kidney Stones - Interesting New Research implicates bacteria as its cause
2. Stem cell research- now Nobel Laureates join the debate
3. Researchers urge caution in using ear tube surgery
4. Paracetamol May Cause Live Damage Warns Consumer Education and Research Centre
5. Spouses and other partners lower blood pressure says new research
6. Researchers Scale to assess the Severity of Epilepsy in Kids
7. Ecstasy shrinks brain!!-researchers unveil the secrets of MDMA.
8. Research of Ritalin
9. New Hair in 15 Days Could Now Be A Possibility Say Researchers
10. Researchers at Cornell University as been reported using research fund by false claims
11. Better Research Rats To Help In Learning About Hypertension
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/5/2015)... Daily Greens™, an organic cold-pressed ... line, Half Pint that will debut nationwide, exclusively ... current offerings, Half Pint is crafted with certified ... other ingredients that are sourced locally whenever possible. ... preserve nutrients and extend shelf life, the organic ...
(Date:3/5/2015)... Obesity can cause the human body ... one drinks each day can help promote weight loss ... water advocate Sharon Kleyne and sports doctor Robert Weil, ... Powers of Water® radio show. , Weil is ... orthotics and sports medicine. His weekly radio show, ...
(Date:3/5/2015)... (PRWEB) March 05, 2015 Hope For The ... Sporting Clay Shoot to be held at Beretta Shooting Grounds ... 2015. All proceeds from the event will benefit Hope For ... of self, restoring the family unit, and restoring hope for ... will honor our nation’s heroes through a day of clay ...
(Date:3/5/2015)... (PRWEB) March 05, 2015 Lakeview ... continued support of the annual American Heart Association’s Heart ... Bret Kolman, Lakeview Regional Chief Executive Officer, is serving ... on Saturday, March 21, 2015 at Fontainebleau State Park ... Lakeview Regional has 20 individual teams participating in this ...
(Date:3/5/2015)... Yorba Linda, CA (PRWEB) March 05, 2015 ... Professor of Neuroscience, Professor of Psychiatry and Psychology ... a keynote presentation at the upcoming BioConference Live ... in neuroscience. , The webcast , ... Schizophrenia and Depression,” is scheduled for Thursday, March ...
Breaking Medicine News(10 mins):Health News:Daily Greens™ Debuts Organic Cold-Pressed Smoothie Line for Kids Exclusively in Whole Foods Markets 2Health News:Daily Greens™ Debuts Organic Cold-Pressed Smoothie Line for Kids Exclusively in Whole Foods Markets 3Health News:Obesity is dehydrating and drinking water promotes weight loss say fresh water advocates 2Health News:Obesity is dehydrating and drinking water promotes weight loss say fresh water advocates 3Health News:Hope For The Warriors Announces New York Clay Shoot to Benefit Military Families 2Health News:Get Your Heart Set on Walking a Better "Path" - Lakeview Regional Medical Center Sponsors Northshore Heart Walk 2Health News:Get Your Heart Set on Walking a Better "Path" - Lakeview Regional Medical Center Sponsors Northshore Heart Walk 3Health News:Anthony Grace, MD, PhD, to Deliver Keynote at BioConference Live Neuroscience 2015 2Health News:Anthony Grace, MD, PhD, to Deliver Keynote at BioConference Live Neuroscience 2015 3
... ... of Health Information Technology , ... Carrollton, GA (PRWEB) June 14, 2010 -- Greenway Medical ... interoperability solution PrimeSuite®, is today launching BlogEHR, an interactive blog site focusing on ...
... LA JOLLA, Calif., June 15, 2010 Without knowing ... regularly take non-steroidal anti-inflammatory drugs (NSAIDs) like aspirin have ... a study appearing in Cancer Cell on ... and their colleagues have figured out how one NSAID, ...
... ... Smoother, Firmer Skin Surface , ... Los Angeles, Calif. (PRWEB) June 14, 2010 -- For many years, ... and achieve a slimmer, smoother and firmer appearance. However, the procedure is not without ...
... the crucifixion of Jesus find little support in historical ... descriptions of crucifixions, says Gunnar Samuelsson, University of Gothenburg, ... topic. Encyclopaedias, monographs and bible commentaries generally agree ... on Golgotha in Jerusalem. There is an ample amount ...
... PROVIDENCE, RI A new study from Rhode Island ... to modulate Parkinson,s disease symptoms. The lead author will ... Stereotactical and Functional Neurosurgery (ASSFN) Biennial Meeting, June 14-16 ... a neurosurgeon at Rhode Island Hospital and the lead ...
... as likely to have breast abnormalities picked up by a ... to research published in the July issue of the ... Wales, UK, compared the findings of 126 women examined by ... breast disease clinic over a 13-month period. They ...
Cached Medicine News:Health News:Industry Leaders Featured in Greenway's BlogEHR 2Health News:Industry Leaders Featured in Greenway's BlogEHR 3Health News:Turning a painkiller into a cancer killer 2Health News:Why More Women are Choosing OptiLipo over Liposuction 2Health News:What do we really know about the crucifixion of Jesus? 2Health News:Specially trained nurse practitioner detected same breast abnormalities as surgeon 2Health News:Specially trained nurse practitioner detected same breast abnormalities as surgeon 3
(Date:3/5/2015)... 5, 2015  AMRI (NASDAQ: AMRI ) ... newly created position of VP of International Sales, effective ... Vice President of Global Sales and Marketing. ... international sales team in an effort to increase worldwide ... segments. Mr. Pettersson will drive strategy for sales and ...
(Date:3/5/2015)... 05, 2015 Research and Markets ( ... "India Pharma Outlook 2015: Accelerating growth to the next ... report to their offering. Domestic ... the 2013 caused by the market,s reaction to the ... to continue to be healthy, as the momentum continues ...
(Date:3/5/2015)... , March 5, 2015  ContraVir Pharmaceuticals, Inc. (NASDAQ: ... the development and commercialization of targeted antiviral therapies, announced ... Annual ROTH Conference, to be held March 8-11, ... James Sapirstein , Chief Executive Officer, ... his live presentation and will be available to participate ...
Breaking Medicine Technology:AMRI Hires VP of International Sales 2India Pharma Outlook 2015: Accelerating growth to the next level - Moving up the value chain beyond Generics 2India Pharma Outlook 2015: Accelerating growth to the next level - Moving up the value chain beyond Generics 3ContraVir to Present at 27th Annual ROTH Conference 2
... Oct. 12 Today at the annual AdvaMed ... provider of Good Promotional Practices software, announced a ... hotline and case management solutions. Together, the companies ... to help Life Sciences companies cope with the ...
... Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX ) today announced that ... general business update on Monday, October 12, 2009, at 8:00 ... parties may access a live webcast of the presentation on ... or by dialing 847-413-3362 and using the passcode 25577870#. ...
Cached Medicine Technology:Prolifiq and EthicsPoint Announce Partnership: 'Automatic Alerts' Help Life Sciences Engage in Good Promotional Practices 2Prolifiq and EthicsPoint Announce Partnership: 'Automatic Alerts' Help Life Sciences Engage in Good Promotional Practices 3
7 mm strong curved blade. Round handle....
3 mm diameter roller blade, 15 mm from angle to tip. Round handle....
No. 4. 0.75 mm wide x 5 mm long, lightly curved tip, offset to the left. Hexagonal handle....
Large. 2.5 mm diameter blade. Angled up 45 degrees. Round handle....
Medicine Products: