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New research identifies more effective tools for detection of colorectal cancer
Date:6/1/2009

percent were correctly diagnosed by the colonoscopists making the optical diagnosis.

"Optical diagnosis allows us to predict accurately whether a polyp should be removed immediately during the colonoscopy. This not only spares the patient the risk involved in the unnecessary removal of non-precancerous polyps, but eliminates the wait time and expense involved in the current protocol of sending biopsies to pathology," said Ana Ignjatovic, BMBCh, endoscopy research fellow at the Wolfson Unit for Endoscopy at St. Mark's Hospital.

Both Dr. Ignjatovic and Brian P. Saunders, MD, director of the Wolfson Unit for Endoscopy, believe that the next steps should be to expand the study beyond an academic center to determine the level of training that would need to be provided before the procedure could be used on a wider scale.

Dr. Ignjatovic will present these data on Tuesday, June 2 at 10:30 a.m. CDT in S406A, McCormick Place.

Risk of Perforation During Colonoscopy: A Systematic Review and Meta-analysis (Abstract #210)

Perforation rates for both diagnostic and therapeutic colonoscopies are quite low and reported rates are decreasing, according to the largest analysis to date of colonoscopy perforation rates.

Using meta-analysis, a type of systematic review that includes formal statistical techniques to combine the results of previous research, investigators under the mentorship of Philip S. Schoenfeld, MD, at the University of Michigan sought to establish an accurate measure of colonoscopy perforation rates. According to previous research, reported rates of perforation in the literature range from as low as 0.01 percent (1 in 10,000) to as high as 1.1 percent (1 in 100).

"Perforation is one of several potential complications of colonoscopy including cardiopulmonary events, hemorrhage and pain," said S. M. Abbas Fehmi, MD, MSc, clinical faculty at University of Pennsylvania School of Medicine. "Of these
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Contact: Aimee Frank
newsroom@gastro.org
301-941-2620
American Gastroenterological Association
Source:Eurekalert

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