Navigation Links
New research helps clinicians predict treatment outcomes for children with OCD

EAST PROVIDENCE, RI New research from the Bradley Hasbro Children's Research Center may help clinicians better predict how a child with obsessive compulsive disorder (OCD) will respond to some of the most commonly used treatment approaches. The findings, published in the October issue of the Journal of the American Academy of Child and Adolescent Psychiatry, could help guide important clinical decisions about the best intervention for children with this often debilitating anxiety disorder.

"Until now, there has been little information about which OCD treatment to recommend to particular pediatric patients," said lead author Abbe Garcia, PhD, director of the Bradley Hasbro Children's Research Center (BHCRC) Pediatric Anxiety Research Clinic. "Our study identified some characteristics of children with OCD that could help us predict which patients are most likely to benefit from particular treatments, similar to a personalized medicine approach."

OCD is an anxiety disorder characterized by recurrent, unwanted thoughts (obsessions) and/or repetitive behaviors (compulsions). The symptoms reported by children are similar to those seen among adults with OCD. According to the American Academy of Child and Adolescent Psychiatry, as many as 1 in 200 children and adolescents struggle with OCD.

Researchers focused on outcomes of the three most commonly used treatment approaches for pediatric OCD: a form of psychotherapy known as cognitive behavioral therapy (CBT) that teaches children to face their fears; sertraline, a selective serotonin reuptake inhibitor (SSRI); and a combination of the two.

They found that children with less severe OCD symptoms, fewer co-existing behavior problems and children whose symptoms cause less impairment in their everyday lives showed greater improvement across all of the treatments. Also, children who were better able to recognize their symptoms as irrational fared better, regardless of the treatment course. In addition, patients from families that were less accommodating of the child's OCD symptoms were also more successful in all treatments.

The study also revealed an intriguing connection between OCD treatment outcome and family history: patients with a parent and/or sibling with OCD did six times worse in CBT than their peers without a family history of OCD. Garcia says this could be due to the nature of CBT, which requires more family support and at-home involvement than medication compliance, something that could be more difficult when a parent or other sibling is also dealing with OCD.

"Based on our findings, cognitive behavioral therapy with or without a concomitant medication is the treatment of choice for children and teens with OCD who do not have a parent or sibling who is also affected," said Garcia. "For those children with a family history, cognitive behavioral therapy in combination with a medication is probably the most effective treatment approach."

The study included 112 children between the ages of 7 and 17 with a primary diagnosis of OCD but who were not currently being treated. The group included roughly even amounts of males and females as well as younger and older children. All participants were randomly assigned to one of four treatment approaches: CBT and setraline; setraline; CBT only; and a placebo. Researchers analyzed how children responded after 12 weeks of treatment using the Children's Yale-Brown Obsessive Compulsive Scale, a clinical tool used to measure a patient's level of impairment and distress.


Contact: Jessica Collins Grimes

Related medicine news :

1. Embedded Mobile & M2M Device revenues to Rise to Almost $19 Billion Globally by 2014, Says Juniper Research
2. 2010 HSR Impact Award recognizes surgical safety research
3. MSU launches first anti-counterfeiting research program
4. Researchers map all the fragile sites of the yeast Saccharomyces cerevisiaes genome
5. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
6. Researchers discover new way to kill pediatric brain tumors
7. Family Research Council: Planned Parenthood Report Oversexualizes Ten-Year-Olds, Undermines Parental Authority
8. Michael J. Fox Foundation Awards $1 Million to Drive Critical New Research Tools and Technologies in Parkinsons Drug Development
9. Luth Researchs IndicatorEDG(TM) Study Finds Americans Hopes of Achieving Their Dreams Are Fading
10. International Diabetes Federation awards $2 million to 9 global diabetes research projects
11. Gladstones Robert Mahley to receive Research!America advocacy award
Post Your Comments:
Related Image:
New research helps clinicians predict treatment outcomes for children with OCD
(Date:11/25/2015)... ... November 25, 2015 , ... For the first time, Vitalalert ... Organizations, One Beat ” campaign. The partnership between the two groups began in 2014 ... MAP International’s cause. , MAP International was founded in 1954 and is an international ...
(Date:11/25/2015)... ... ... On November 25, 2015, officials of Narconon Arrowhead , the drug rehabilitation ... new cutting edge recovery program that has been 50 years in the making. ... with the purpose to free addicts from the symptoms and negative behaviors of addiction. ...
(Date:11/25/2015)... ... ... Smiles by Stevens is pleased to announce the addition of Botox® for ... aware of the benefits of Botox® in the treatment of moderate facial wrinkling, few ... and pain as a result of Jaw Tension, TMJ (temporo-mandibular joint) disorder, and Bruxism ...
(Date:11/25/2015)... ... November 25, 2015 , ... In an ongoing Clinical Study conducted by an ... IL, UV Angel is evaluating the efficacy of its product and its disinfection protocol. ... 30 beds) from May 2014 through October 2015 at a 360-bed, acute-care, academic medical ...
(Date:11/25/2015)... Spring, Md (PRWEB) , ... November 25, 2015 ... ... Pulmonary Hypertension Association (PHA) announces the nation’s Periwinkle Pioneers, individuals and groups responsible ... history of this disease. The Periwinkle Pioneers, nominated by the public, will receive ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... 2015 Kitov Pharma ceuticals ... a biopharmaceutical company focused on the development of therapeutic ... today announced the closing of its previously announced underwritten ... ), each representing 20 ordinary shares of the Company, ... ADSs and warrants were issued in a fixed combination ...
(Date:11/25/2015)...  Today AVACEN Medical announced the issue of United States patent No. ... ". This patent shields the company,s AVACEN 100 dry heat therapy medical device and specific methods ... Photo - ... ... ...
(Date:11/25/2015)... , Nov. 25, 2015 USP 800 ... drug preparations (e.g. pharmacists, pharmacy technicians, nurses, physicians, ... technicians). The chapter also covers all entities which ... pharmacies, hospitals, other healthcare institutions, patient treatment clinics, ... --> --> What is ...
Breaking Medicine Technology: