Navigation Links
New research from Rhode Island Hospital may help predict outcomes for stomach cancer patients
Date:7/16/2008

PROVIDENCE, R.I. Researchers at Rhode Island Hospital have identified two potential molecular markers that may predict outcomes for patients with stomach cancer, one of the most common and fatal cancers worldwide.

According to the study, published in the July 1 issue of Clinical Cancer Research, patients who had poor outcomes following surgery for stomach cancer also had extremely low amounts of two proteins, known as gastrokine 1 and 2 (GKN1 and GKN2), which are produced by normal stomach cells.

The study's findings confirm previous research showing that once stomach cells become cancerous, they manufacture very low amounts of GKN1 and GKN2. However, this is the first known study to link these low protein levels with outcomes following stomach cancer surgery. Researchers say this discovery could eventually help physicians better determine and individualize therapy for stomach cancer, including which patients should be offered chemotherapy and other treatments in addition to surgery.

"Unfortunately, stomach cancer is difficult to cure unless it's discovered early, but because the early stage of the disease has very few symptoms, the cancer is usually advanced by the time it's diagnosed," says lead author Steven Moss, MD, a gastroenterologist with Rhode Island Hospital and an associate professor of medicine at The Warren Alpert Medical School of Brown University.

"That's what makes our findings so significant, because if the potential markers identified in our study can help predict a patient's prognosis, we can decide right away which course of action to take and hopefully help patients live longer and more comfortably," he adds.

According to the National Cancer Institute, approximately 760,000 cases of stomach cancer are diagnosed worldwide each year. Microscopically, stomach cancers can be subdivided into those which appear "diffuse" (a more aggressive form of cancer that can occur throughout the stomac
'/>"/>

Contact: Jessica Collins Grimes
jgrimes2@lifespan.org
401-432-1328
Lifespan
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. Children of depressed moms do better when dad is involved, SLU researcher finds
3. UCLA researchers identify markers that may predict diabetes in still-healthy people
4. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
5. New research shows how chronic stress worsens neurodegenerative disease course
6. New research explores newborn in-hospital weight loss
7. Research may unlock mystery of autisms origin in the brain
8. Bipolar disorder relapses halved by Melbourne researchers
9. HIVs impact in Zimbabwe explored in new research
10. U.S. Research Funding Continues to Flatten as U.S. Health Costs Climb - in August 31 Science
11. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2015)... ... July 28, 2015 , ... Healthpointe ’s Cosmetic Laser Institute in Anaheim ... smooth state, and reduces the appearance of fine lines and wrinkles. , According to ... to instantly add volume to your cheek area to correct age-related volume loss in ...
(Date:7/28/2015)... ... ... Bipolar disorder is often associated with mood swings ranging from depressive lows ... World Health Organization (WHO) has reported that bipolar disorder affects about 60 million people ... United States has the highest lifetime rate of bipolar disorder at 4.4% affecting 14 ...
(Date:7/28/2015)... ... 28, 2015 , ... A new Taiwanese study suggests that ... in the general population. Surviving Mesothelioma has just posted an article detailing the ... Taiwan’s National Health Research Institutes and three Taiwanese universities evaluated the health records ...
(Date:7/28/2015)... ... ... A new study published by HealthDay News on June 24, 2015, entitled ... possible new treatment option for people living with fibromyalgia – hyperbaric oxygen therapy treatments ... per week, patients experienced a significant decrease in pain, fatigue, and other symptoms of ...
(Date:7/28/2015)... (PRWEB) , ... July 28, 2015 , ... There has ... most people think of highways, bridges and railroads, often overlooked is the over ... our homes and buildings and into sewage treatment facilities. According to the American ...
Breaking Medicine News(10 mins):Health News:Healthpointe’s Cosmetic Laser Institute Now Providing Juvéderm Voluma XC in Anaheim 2Health News:Healthpointe’s Cosmetic Laser Institute Now Providing Juvéderm Voluma XC in Anaheim 3Health News:"I Am Not I" Music Video Raises Bipolar Disorder Awareness 2Health News:New Findings Suggest Mesothelioma is Not the Only Cancer Threat for Shipbreakers, According to Surviving Mesothelioma 2Health News:Recovery Specialists Discuss How Oxygen Therapy Can Ease Fibromyalgia 2Health News:Recovery Specialists Discuss How Oxygen Therapy Can Ease Fibromyalgia 3Health News:With an Infrastructure Spending Bill on the Horizon, RestorationEze Discusses the Impact an Aging Sewer System is Having on Homeowners 2Health News:With an Infrastructure Spending Bill on the Horizon, RestorationEze Discusses the Impact an Aging Sewer System is Having on Homeowners 3
... "As a physician,you hear all sorts of excuses for ... Medical Director of First Coast Family Medicine and clinical,spokesperson ... common that Dr. Hashey reports is the excuse that ... couldn,t be farther from the truth.,The flu shot is ...
... October 17 - For the Nine Months (to 31 ... Months Almost Six-Fold Growth in EBIT to EUR34.8m (EUR6.2m) - ... Substantial Debt Reduction and Fall in Interest Charges Since the IPO ... Our,Full-Year Forecast for 2007." In the first nine months of ...
... hold a press availability tomorrow, Wednesday, October 17, at 10:30,a.m. ... 2-year-old,from Tampa, Fla., who was born with a serious heart ... is on Capitol Hill urging Members of,Congress to vote to ... 10 million children., WHO: Speaker Nancy ...
... the U.S. Food and Drug,Administration,s (FDA,s) Cardiovascular ... majority of members voted to recommend the ... FOSRENOL(R),(lanthanum carbonate), to treat hyperphosphatemia (elevated levels ... disease (CKD) Stage 4 patients.,Currently, FOSRENOL is ...
... the race to the 2008 elections,heats up, nearly every ... coverage. "But when it comes to the already ... of industry players is a more,overarching consideration than the ... Standard & Poor,s Ratings Services,in a report published Oct. ...
... yogurt(TM) in an easy-to-swallow caplet., VANCOUVER, Wash., ... of AccuFlora Pro-Biotic Acidophilus, a combination of,five types ... a healthy immune system with the good stuff ... MayoClinic.com, there is growing public and scientific,interest in ...
Cached Medicine News:Health News:Flu Myths Abound in Flu Season 2Health News:Growth Trend for Gerresheimer Continues Unabated - Debt Reduction 2Health News:Growth Trend for Gerresheimer Continues Unabated - Debt Reduction 3Health News:Growth Trend for Gerresheimer Continues Unabated - Debt Reduction 4Health News:Growth Trend for Gerresheimer Continues Unabated - Debt Reduction 5Health News:FDA Advisory Committee Votes in Favor of Earlier Use of Phosphate Binders in Stage 4 Kidney Disease Patients With Hyperphosphatemia 2Health News:FDA Advisory Committee Votes in Favor of Earlier Use of Phosphate Binders in Stage 4 Kidney Disease Patients With Hyperphosphatemia 3Health News:FDA Advisory Committee Votes in Favor of Earlier Use of Phosphate Binders in Stage 4 Kidney Disease Patients With Hyperphosphatemia 4Health News:FDA Advisory Committee Votes in Favor of Earlier Use of Phosphate Binders in Stage 4 Kidney Disease Patients With Hyperphosphatemia 5Health News:FDA Advisory Committee Votes in Favor of Earlier Use of Phosphate Binders in Stage 4 Kidney Disease Patients With Hyperphosphatemia 6Health News:FDA Advisory Committee Votes in Favor of Earlier Use of Phosphate Binders in Stage 4 Kidney Disease Patients With Hyperphosphatemia 7Health News:S&P: Leverage Tops Politics as Primary Credit Concern for U.S. Health Care Companies, Says S&P 2Health News:Northwest Natural Products Introduces AccuFlora(R) 2
(Date:7/28/2015)... , July 28, 2015 ... new research report with market overview, trends, ... forecast, porter analysis, recent developments, competitive scenario ... Global Industry Insight: Human Insulin Market Development ...      (Logo: http://photos.prnewswire.com/prnh/20150727/756778) Explore more ...
(Date:7/28/2015)... LINCOLNSHIRE, Ill. , July 28, 2015 ... acumen on par with their levels of clinical excellence. ... (AACC) Annual Meeting & Clinical Lab Expo, Sysmex is ... deliver a comprehensive and intuitive ecosystem that will help ... four key areas, Sysmex aims to add even more ...
(Date:7/28/2015)... July 28, 2015 Rigel Pharmaceuticals, Inc. (Nasdaq: ... report its second quarter 2015 financial results after market ... management will follow the announcement with a live ... (1:30pm Pacific Time) to discuss the financial results. ... call by dialing 855-892-1489 (domestic) or 720-634-2939 (international) ...
Breaking Medicine Technology:Global Human Insulin Market (Size of $24 billion in 2014) to Witness 13% CAGR During 2015 - 2020 2Global Human Insulin Market (Size of $24 billion in 2014) to Witness 13% CAGR During 2015 - 2020 3Global Human Insulin Market (Size of $24 billion in 2014) to Witness 13% CAGR During 2015 - 2020 4Global Human Insulin Market (Size of $24 billion in 2014) to Witness 13% CAGR During 2015 - 2020 5Sysmex Moves Beyond a Better Box 2Sysmex Moves Beyond a Better Box 3Sysmex Moves Beyond a Better Box 4Rigel Announces Conference Call and Webcast to Report Second Quarter 2015 Financial Results 2
Therapeutic Drug Calibrator Series...
The IRN method used on the Dimension clinical chemistry system is an in vitro diagnostic test intended for the quantitative determination of iron in serum....
The AST method used on the Dimension clinical chemistry system is an in vitro diagnostic test intended for the quantitative determination of aspartate aminotransferase activity in serum or plasma...
For the quantitative in vitro determination of Aspartate Aminotransferase (AST) in serum and plasma....
Medicine Products: